Zobrazeno 1 - 10
of 3 840
pro vyhledávání: '"Martine J"'
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Preventing metabolic syndrome (MetS) and frailty in older adults is crucial for healthy aging. The association between MetS and physical frailty is well-documented, with low-grade inflammation as potential explanation. However, th
Externí odkaz:
https://doaj.org/article/62be91e1c1944594a61b1dd0d795f9fb
Autor:
Florentine S. Hilbers, Coralie Poncet, Konstantinos Tryfonidis, Giuseppe Viale, Suzette Delaloge, Jean-Yves Pierga, Etienne G. C. Brain, Isabel T. Rubio, Alastair M. Thompson, Emiel J. T. Rutgers, Martine J. Piccart, Laura J. van ’t Veer, Fatima Cardoso
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Small, hormone receptor-positive (HR+), HER2-negative (HER2-), lymph node-negative breast cancers are associated with relatively low rates of disease recurrence and have therefore been underrepresented in clinical trials assessing the effect
Externí odkaz:
https://doaj.org/article/d632b4b675464734a9b0c41dc7dee912
Autor:
Sandy Van Hemelryck, Erika Van Landuyt, Jay Ariyawansa, Martyn Palmer, Martine J. C. Kothe, Caroline Pollefliet
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Objective Darunavir (DRV) is a P-glycoprotein (P-gp) inhibitor. Dabigatran etexilate, prodrug of the anticoagulant dabigatran, is a P-gp probe substrate. This study evaluated the effect of single and multiple doses of DRV, coadministered wit
Externí odkaz:
https://doaj.org/article/8f9ffe32fdc24ef8bc61f8b1a1066bf2
Autor:
Sander W Tas, Dieneke Schonenberg-Meinema, J Merlijn van den Berg, Sylvia Kamphuis, Marjan A Versnel, Mohamed Javad Wahadat, Sandy C Bergkamp, Amara Nassar-Sheikh Rashid, Mariken P Gruppen, Nick D Bergkamp, Martine J Smit
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 2 (2024)
Objectives In childhood-onset SLE (cSLE), patients have an increased risk of premature atherosclerosis. The pathophysiological mechanisms for this premature atherosclerosis are not yet completely understood, but besides traditional risk factors, the
Externí odkaz:
https://doaj.org/article/5f9342529e30440fbdfe69e24f3bdd31
Autor:
Roman R. Schlimgen, Francis C. Peterson, Raimond Heukers, Martine J. Smit, John D. McCorvy, Brian F. Volkman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract G protein-coupled receptors (GPCRs) are pivotal therapeutic targets, but their complex structure poses challenges for effective drug design. Nanobodies, or single-domain antibodies, have emerged as a promising therapeutic strategy to target
Externí odkaz:
https://doaj.org/article/52636f4e898c4c9caf197813d718a9df
Autor:
Sander M J van Kuijk, François Maissan, Martine J Verwoerd, Harriët Wittink, Marc Teunis, Rob J E M Smeets
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Objective To develop and internally validate a prognostic model to predict chronic pain after a new episode of acute or subacute non-specific idiopathic, non-traumatic neck pain in patients presenting to physiotherapy primary care, emphasising modifi
Externí odkaz:
https://doaj.org/article/ee1b42d13ace4faf8645ab1a4ba483f8
Autor:
Gamal A. Wakileh, Philipp Bierholz, Mara Kotthoff, Margaretha A. Skowron, Felix Bremmer, Alexa Stephan, Stephanie M. Anbuhl, Raimond Heukers, Martine J. Smit, Philipp Ströbel, Daniel Nettersheim
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-5 (2023)
Abstract Being stimulated by the chemokine CXCL12, the CXCR4 / CXCR7 cascade is involved in tumor proliferation, migration, and metastasis. The interaction between CXCL12, secreted by cells from the microenvironment, and its receptors is complex and
Externí odkaz:
https://doaj.org/article/7c03766aefb5452d89e9a05381e22674
Autor:
Hope S. Rugo, Sara M. Tolaney, Delphine Loirat, Kevin Punie, Aditya Bardia, Sara A. Hurvitz, Joyce O’Shaughnessy, Javier Cortés, Véronique Diéras, Lisa A. Carey, Luca Gianni, Martine J. Piccart, Sibylle Loibl, David M. Goldenberg, Quan Hong, Martin Olivo, Loretta M. Itri, Kevin Kalinsky
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/abb00ee86ac244e6959147aeb2f4a725
Autor:
Arwin Groenewoud, Jie Yin, Maria Chiara Gelmi, Samar Alsafadi, Fariba Nemati, Didier Decaudin, Sergio Roman-Roman, Helen Kalirai, Sarah E. Coupland, Aart G. Jochemsen, Martine J. Jager, Felix B. Engel, B. E. Snaar-Jagalska
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Uveal melanoma (UM) has a high risk to progress to metastatic disease with a median survival of 3.9 months after metastases detection, as metastatic UM responds poorly to conventional and targeted chemotherapy and is largely refractory to im
Externí odkaz:
https://doaj.org/article/35f875d9b6ee4910a5099e5b1b9ef6e8
Autor:
Martijn Burger, Martine J. H. Coun, Jol Stoffers, Steven Van Den Heuvel, Arne Vanderstukken, Thomas Van Waeyenberg
Publikováno v:
Frontiers in Psychology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/2ee5faf3ff3b43d7ad7805511eafb57b