Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Martine Hascoët"'
Autor:
Michel Bourin, Martine Hascoët
Publikováno v:
Current Psychopharmacologye. 1:2-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fc6058575b4bb54e0ae07fc74f50da
https://doi.org/10.2174/2211556011201010002
https://doi.org/10.2174/2211556011201010002
Autor:
Michel Bourin, Martine Hascoët
Publikováno v:
Behavioural Brain Research. 208:352-358
Etifoxine is an anxiolytic compound structurally unrelated to benzodiazepine and neurosteroids but potentiating GABA A receptor function by a dual mode of action including a direct positive allosteric modulation through a site distinct from that of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef56d55e7e85e44929ccef29f45e0b63
https://doi.org/10.1016/j.bbr.2009.11.046
https://doi.org/10.1016/j.bbr.2009.11.046
Publikováno v:
Behavioural Brain Research. 205:421-425
Topiramate and phenytoin possess mood stabilizing properties. The mechanism of action of anticonvulsants used in the treatment of bipolar depression is complex and still not completely elucidated. Na+ channels are present at distinct sites in neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2def244218616f0a825ec442b512d107
https://doi.org/10.1016/j.bbr.2009.07.030
https://doi.org/10.1016/j.bbr.2009.07.030
Publikováno v:
Current Drug Targets. 10:1052-1060
Antidepressant drugs modify in different ways the activity of neurons, by increasing monoamines levels and by modulating ion channels. Sodium channels are molecular targets for antiepileptic drugs, which can also be mood stabilizers (i.e. lamotrigine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196c29a6916af1e77bf95f0933087e3a
https://doi.org/10.2174/138945009789735138
https://doi.org/10.2174/138945009789735138
Publikováno v:
Psychopharmacology. 206:97-107
A deficiency in brain monoamine systems (serotonin, dopamine, and/or norepinephrine) have long been hypothesized for the pathogenesis of depression. Drugs enhancing neurotransmission of those monoamines have been proven to have antidepressant effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df974007a0deb1121d75b1e2001600e
https://doi.org/10.1007/s00213-009-1583-7
https://doi.org/10.1007/s00213-009-1583-7
Publikováno v:
European Neuropsychopharmacology. 18:41-47
Abolishment of anxiolytic-like effects of diazepam occurs during re-exposure to some animal tests of anxiety. We investigated the loss of anxiolytic-like effects of diazepam during Trial 2 on previously undrugged mice, namely one-trial tolerance (OTT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f80090e67c881313aab1cbc8ee0ba8c
https://doi.org/10.1016/j.euroneuro.2007.04.006
https://doi.org/10.1016/j.euroneuro.2007.04.006
Publikováno v:
Fundamental & Clinical Pharmacology. 21:567-574
Among the multiple possibilities to study human pathologies, animal models remain one of the most used pathways. They allow to access to unavailable answers in human patients and to learn about mechanisms of action of drugs. Primarily developed with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2935b265b436d347a5268c5125bb2a74
https://doi.org/10.1111/j.1472-8206.2007.00526.x
https://doi.org/10.1111/j.1472-8206.2007.00526.x
Publikováno v:
Behavioural Brain Research. 177:214-226
Animal models of anxiety remain a useful tool for evaluating the anxiolytic-like effect of new treatments. Even though many tests are similarly based on exploration tasks, using more than one animal model is all the more recommended since there are q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723f7f4c0467c54ae49afe460252aba1
https://doi.org/10.1016/j.bbr.2006.11.031
https://doi.org/10.1016/j.bbr.2006.11.031
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 30:873-880
The four-plates test (FPT) is an animal model of anxiety in which the exploration of the novel surroundings is suppressed by the delivery of a mild electric foot shock. The anti-nociceptive system has been reported to be activated by a variety of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4015d5875be67425f44a748856b625ed
https://doi.org/10.1016/j.pnpbp.2005.11.036
https://doi.org/10.1016/j.pnpbp.2005.11.036
Publikováno v:
CNS Drug Reviews. 10:219-229
Several studies have suggested that the antipsychotic compound, cyamemazine, possesses anxiolytic properties in humans. The original pharmacological profile of cyamemazine (D(2), 5‐HT(2A), 5‐HT(2C), and 5‐HT(3) receptor antagonist), which was e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522ad8ea193c9632597c4f5c500a9e96
https://doi.org/10.1111/j.1527-3458.2004.tb00023.x
https://doi.org/10.1111/j.1527-3458.2004.tb00023.x