Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Martine Guillier"'
Autor:
Marie-Laure Bonnet, François Guilhot, Ali G. Turhan, Martine Guillier, Catherine Lacout, Stephane Flamant, Véronique Mansat de Mas, Peggy Jarrier, Paul Coppo, William Vainchenker
Publikováno v:
British Journal of Haematology. 134:171-179
Chronic myeloid leukaemia (CML) is characterised by a progression from a chronic towards an acute phase. We previously reported that signal transducer and activator of transcription 3 (STAT3), a major oncogenic signalling protein, is the target of p2
Autor:
Thierry Kortulewski, Stephane Flamant, Ali G. Turhan, J. H. Bourhis, François Guilhot, Martine Guillier, Marie-Laure Bonnet, D. Tronik-Le Roux, William Vainchenker, Aymeric Dugray
Publikováno v:
Biochemical and Biophysical Research Communications. 333:1378-1384
Chronic myelogenous leukemia (CML) is characterized by its hallmark oncogene BCR-ABL and the progression from a chronic phase toward an acute leukemia, with a differentiation arrest of the leukemic clone. In the present study, we conducted a microarr
Publikováno v:
Oncogene. 19:1147-1152
Previous studies have led to the proposal that a single molecule of Cki can associate with the cyclin/Cdk complex to repress its activity. On the other hand, multiple inhibitor molecules are required to inhibit Cdks. In the present work, by using dif
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1174:143-152
A major CSF-1 (Colony-Stimulating Factor 1) mRNA 4.0 kb long was expressed during the proliferation of the L6 alpha 1 rat myogenic cells and was down-regulated after their differentiation into myotubes. A complete cDNA encoding the rat CSF-1 gene (rm
Publikováno v:
Growth Factors. 6:209-218
We have isolated and sequenced a cDNA (mrfms) encoding rat c-fms gene (CSF-1 receptor) from proliferating L6 alpha 1 myoblasts. The predicted amino acid sequence was highly identical with the c-fms protein found in monocytes and macrophages (98, 76 a
Autor:
Frédéric Mazurier, Ali G. Turhan, Celine Haond, William Vainchenker, Martine Guillier, Françoise Farace, Yann Lécluse
Publikováno v:
Cell research. 17(9)
The murine skeletal muscle contains hematopoietic stem cells, but this potential has so far not been studied quantitatively or qualitatively in vitro. To quantify the hematopoietic stem cell potential, we have used highly purified SP/CD45(+) cells in
Autor:
Jean-Henri Bourhis, Stephane Flamant, Rami Kotb, Cristina Tourino, Pierre Fenaux, Marie-Laure Bonnet, Claude Preudhomme, Alain Bernheim, Martine Guillier, Valérie Soenen-Cornu, Ali G. Turhan
Publikováno v:
Oncogene. 24(15)
Myelodysplastic syndromes (MDS) are clonal malignant stem cell disorders characterized by inefficient hematopoiesis. The role of the marrow microenvironment in the pathogenesis of the disease has been controversial and no study has been performed so
Autor:
Marie-Laure Bonnet, Françoise Farace, Greissenger N, Vantelon Jm, Martine Guillier, Assari S, Marracho Mc, Catherine Boccaccio, Fariba Nemati, J. H. Bourhis, Jean Michon, Ali G. Turhan, A. L. Bennaceur, Didier Decaudin
Publikováno v:
Bone marrow transplantation. 34(12)
To evaluate the impact of ex vivo expanded megakaryocyte (MK) progenitors on high-dose chemotherapy-induced thrombocytopenia, we conducted a phase II study in 10 patients with relapsed lymphoma. Two fractions of peripheral blood progenitor cells (PBP
Publikováno v:
Biochemical and biophysical research communications. 323(3)
To study the hierarchical levels of stem cell targets for ABL-kinase domain mutations in CML, highly purified CD34+CD38− and CD34+CD38+ cell populations and their LTC-IC-derived progeny were analyzed in four patients at diagnosis ( n = 1) or in adv
Autor:
Bernard Zalc, Ali G. Turhan, Celine Haond, Sabrina Badaoui, Martine Guillier, Françoise Farace, Jean-Leon Thomas, William Vainchenker, Laetitita Prestoz, Paule Opolon
Publikováno v:
Stem cells and development. 13(1)
Muscle tissue of adult mice has been shown to contain stem cells with hematopoietic repopulation ability in vivo. To determine the functional characteristics of stem cells giving rise to this hematopoietic activity, we have performed hematopoietic re