Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Martine Guillermier"'
Autor:
Audrey Fayard, Alexis Fenyi, Sonia Lavisse, Sandra Dovero, Luc Bousset, Tracy Bellande, Sophie Lecourtois, Christophe Jouy, Martine Guillermier, Caroline Jan, Pauline Gipchtein, Benjamin Dehay, Erwan Bezard, Ronald Melki, Philippe Hantraye, Romina Aron Badin
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106086- (2023)
The role of alpha-synuclein in Parkinson's disease has been heavily investigated since its discovery as a component of Lewy bodies. Recent rodent data demonstrate that alpha-synuclein strain structure is critical for differential propagation and toxi
Externí odkaz:
https://doaj.org/article/fc8319213762496b8b5facb25a352826
Autor:
Suzanne Lam, Fanny Petit, Anne-Sophie Hérard, Susana Boluda, Sabiha Eddarkaoui, Martine Guillermier, The Brain Bank Neuro-C. E. B. Neuropathology Network, Luc Buée, Charles Duyckaerts, Stéphane Haïk, Jean-Luc Picq, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Abstract Amyloid-β (Aβ) pathology transmission has been described in patients following iatrogenic exposure to compounds contaminated with Aβ proteins. It can induce cerebral Aβ angiopathy resulting in brain hemorrhages and devastating clinical i
Externí odkaz:
https://doaj.org/article/691891eba277482da3cf8c51aa1b5311
Autor:
Sébastien Goutal, Martine Guillermier, Guillaume Becker, Mylène Gaudin, Yann Bramoullé, André Luxen, Christian Lemaire, Alain Plenevaux, Eric Salmon, Philippe Hantraye, Olivier Barret, Nadja Van Camp
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background Positron Emission Tomography (PET) imaging of the Synaptic Vesicle glycoprotein (SV) 2A is a new tool to quantify synaptic density. [18F]UCB-H was one of the first promising SV2A-ligands to be labelled and used in vivo in rodent a
Externí odkaz:
https://doaj.org/article/6d181ae0a04a4f74826c698f97fe1723
Autor:
Anne-Sophie Hérard, Fanny Petit, Charlotte Gary, Martine Guillermier, Susana Boluda, Clément M. Garin, The Brainbank Neuro-CEB Neuropathology Network, Suzanne Lam, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as after cerebral surgeries. Exper
Externí odkaz:
https://doaj.org/article/e5c5d8960af64e8e93784c6732f96349
Autor:
Noémie Cresto, Marie-Claude Gaillard, Camille Gardier, Francesco Gubinelli, Elsa Diguet, Déborah Bellet, Laurine Legroux, Julien Mitja, Gwenaëlle Auregan, Martine Guillermier, Charlène Josephine, Caroline Jan, Noëlle Dufour, Alain Joliot, Philippe Hantraye, Gilles Bonvento, Nicole Déglon, Alexis-Pierre Bemelmans, Karine Cambon, Géraldine Liot, Emmanuel Brouillet
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The G2019S substitution in the kinase domain of LRRK2 (LRRK2G2019S) is the most prevalent mutation associated with Parkinson's disease (PD). Neurotoxic effects of LRRK2G2019S are thought to result from an increase in its kinase activity as compared t
Externí odkaz:
https://doaj.org/article/f99d8776c12c4a7bb6880f866319890e
Autor:
Sébastien Goutal, Nicolas Tournier, Martine Guillermier, Nadja Van Camp, Olivier Barret, Mylène Gaudin, Michel Bottlaender, Philippe Hantraye, Sonia Lavisse
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240228 (2020)
IntroductionKnowledge of the repeatability of quantitative parameters derived from [18F]FDG PET images is essential to define the group size and allow correct interpretation. Here we tested repeatability and accuracy of different [18F]FDG absolute an
Externí odkaz:
https://doaj.org/article/51bb3114c4074d75b8a6f16febedf038
Autor:
Kelly Ceyzériat, Lucile Ben Haim, Audrey Denizot, Dylan Pommier, Marco Matos, Océane Guillemaud, Marie-Ange Palomares, Laurene Abjean, Fanny Petit, Pauline Gipchtein, Marie-Claude Gaillard, Martine Guillermier, Sueva Bernier, Mylène Gaudin, Gwenaëlle Aurégan, Charlène Joséphine, Nathalie Déchamps, Julien Veran, Valentin Langlais, Karine Cambon, Alexis P Bemelmans, Jan Baijer, Gilles Bonvento, Marc Dhenain, Jean-François Deleuze, Stéphane H R Oliet, Emmanuel Brouillet, Philippe Hantraye, Maria-Angeles Carrillo-de Sauvage, Robert Olaso, Aude Panatier, Carole Escartin
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-23 (2018)
Abstract Astrocyte reactivity and neuroinflammation are hallmarks of CNS pathological conditions such as Alzheimer’s disease. However, the specific role of reactive astrocytes is still debated. This controversy may stem from the fact that most stra
Externí odkaz:
https://doaj.org/article/5dde870f4e784d2e9f9227fff940a15d
Autor:
Noémie Cresto, Camille Gardier, Marie-Claude Gaillard, Francesco Gubinelli, Pauline Roost, Daniela Molina, Charlène Josephine, Noëlle Dufour, Gwenaëlle Auregan, Martine Guillermier, Suéva Bernier, Caroline Jan, Pauline Gipchtein, Philippe Hantraye, Marie-Christine Chartier-Harlin, Gilles Bonvento, Nadja Van Camp, Jean-Marc Taymans, Karine Cambon, Géraldine Liot, Alexis-Pierre Bemelmans, Emmanuel Brouillet
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6760 (2021)
Alpha-synuclein (α-syn) and leucine-rich repeat kinase 2 (LRRK2) play crucial roles in Parkinson’s disease (PD). They may functionally interact to induce the degeneration of dopaminergic (DA) neurons via mechanisms that are not yet fully understoo
Externí odkaz:
https://doaj.org/article/22c7a6ea143b4f2585dbefbd517cfee2
Autor:
Sonia Lavisse, Susannah Williams, Sophie Lecourtois, Nadja van Camp, Martine Guillermier, Pauline Gipchtein, Caroline Jan, Sébastien Goutal, Leopold Eymin, Julien Valette, Thierry Delzescaux, Anselme L. Perrier, Philippe Hantraye, Romina Aron Badin
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104484- (2019)
As research progresses in the understanding of the molecular and cellular mechanisms underlying neurodegenerative diseases like Huntington's disease (HD) and expands towards preclinical work for the development of new therapies, highly relevant anima
Externí odkaz:
https://doaj.org/article/99da11f1b6c04114ab78db28f91a86c8
Autor:
Fabien Pifferi, Olène Dorieux, Christian-Alexandre Castellano, Etienne Croteau, Marie Masson, Martine Guillermier, Nadja Van Camp, Philippe Guesnet, Jean-Marc Alessandri, Stephen Cunnane, Marc Dhenain, Fabienne Aujard
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 8, Pp 1511-1518 (2015)
Decreased brain content of DHA, the most abundant long-chain n-3 polyunsaturated fatty acid (n-3 LCPUFA) in the brain, is accompanied by severe neurosensorial impairments linked to impaired neurotransmission and impaired brain glucose utilization. In
Externí odkaz:
https://doaj.org/article/91287950f92240608c85b0efb4cfc719