Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Martine Grandsaigne"'
Autor:
Yambasu A. Brewah, Marina Pretolani, Séverine Létuvé, Martine Grandsaigne, Marie-Christine Dombret, Alison A. Humbles, Homa Adle, Roland Kolbeck, Anthony J. Coyle, Alexander Kozhich, Michel Aubier
Publikováno v:
The American Journal of Pathology. 176:638-649
Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have investigated whether chitotriosidase (ChTRase) and acidic mammalian chitinase, two chitinases
Autor:
Michel Aubier, Isabelle Mosnier, Martine Grandsaigne, Benoit Feger, Delphine El Mehdi, Jean-Marie Zahm, Laurent Benayoun, Marie-Christine Dombret, Joël Depondt, Marina Pretolani, Anne Druilhe
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:276-282
Abnormal epithelial repair to damage participates in airway remodeling in asthma by the paracrine regulation of mesenchymal cell functions. Retinoids control epithelial functions through nuclear retinoic acid receptor (RAR) and retinoid X receptor (R
Changes in airway inflammation following nasal allergic challenge in patients with seasonal rhinitis
Autor:
Michel Aubier, Marcel Bonay, Véronique Leçon-Malas, Martine Grandsaigne, Philippe Ravaud, Monique Dehoux, Catherine Neukirch
Publikováno v:
Allergy. 61:111-118
Background: Seasonal allergic rhinitis could predispose to the development of chronic bronchial inflammation as observed in asthma. However, direct links between nasal inflammation, bronchial inflammation and airway responsiveness in patients with se
Autor:
Anne Bergeron, Marcel Bonay, Martine Grandsaigne, Abdellatif Tazi, Paul Soler, Allan J. Hance
Publikováno v:
Thorax. 51:611-614
BACKGROUND: Pulmonary histiocytosis X is a disorder characterised by the presence of destructive granulomas preferentially involving distal bronchioles, that contain numerous activated Langerhans' cells. Recent studies have shown that granulocyte-mac
Autor:
Gary P. Sims, Marie-Christine Dombret, Marielle Maret, Séverine Létuvé, Martine Grandsaigne, Michel Aubier, Marina Pretolani, Nassima Ferhani, Alexander Kozhich, Roland Kolbeck, Olivier Thibaudeau, Anthony J. Coyle
Publikováno v:
American journal of respiratory and critical care medicine. 181(9)
Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation and remodeling. High-mobility group box 1 (HMGB1), a nuclear protein that is released during inflammation and repair, interacts with proinflammatory cytokines and wi
Autor:
Martine Grandsaigne, Anthony J. Coyle, Séverine Létuvé, Peter A. Kiener, Marie-Christine Dombret, Jennifer L. Reed, Michel Aubier, Alexander Kozhich, Marina Pretolani, Nassim Arouche
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 181(7)
YKL-40 is a chitin-binding protein that is elevated in patients with various inflammatory conditions associated with ongoing remodeling. We investigated whether the levels of YKL-40 were up-regulated in the circulation and the airways of patients wit
Autor:
Susan He, Jack A. Elias, Marie-Christine Dombret, Mark R. Cullen, Chun Geun Lee, Yun M. Shim, Nizar N. Jarjour, Geoffrey L. Chupp, Jennifer L. Reed, Michel Aubier, Marina Pretolani, Martine Grandsaigne, Carole Holm, Anthony J. Coyle, Peter A. Kiener, James Dziura
Publikováno v:
The New England journal of medicine. 357(20)
The evolutionarily conserved 18-glycosyl-hydrolase family contains true chitinases and chitinase-like proteins that lack enzymatic activity. Acidic mammalian chitinase has recently been associated with animal models of asthma. The related chitinase-l
Publikováno v:
FEMS immunology and medical microbiology. 46(3)
Changes that may modify the capacity of macrophages to control mycobacterial growth could favour the reactivation of bacillary proliferation within protective granulomas developed in response to mycobacterial infection. There is increasing evidence t
Diesel particles increase phosphatidylcholine release through a NO pathway in alveolar type II cells
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 282(5)
Diesel exhaust particles (DEPs) have been shown in vivo as well as in vitro to affect the respiratory function and in particular the immune response to infection and allergens. In the current study, we investigated the effect of DEPs on the productio
Autor:
Martine Grandsaigne, Abdellatif Tazi, P Soler, Allan J. Hance, Francine Bouchonnet, L Boumsell
GM-CSF has been shown to be important for the survival and function of cells of dendritic cell/Langerhans cell (LC) lineage in vitro. Since these cells have been demonstrated to infiltrate human lung and some lung carcinomas, we hypothesized that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc6111ccfb678017e4c235a63f39b2d
https://europepmc.org/articles/PMC287979/
https://europepmc.org/articles/PMC287979/