Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martine Esclangon"'
Autor:
Martine Esclangon, Corinne Thomas, Sylvaine Galiègue, Jean-Claude Vernières, Estelle Bribes, Raymond Paul, Bernard Bourrie, Laurent Garcia, Nathalie De Nys, Pierre Casellas, Pierre Lair
Publikováno v:
European Journal of Pharmacology. 456:123-131
SSR125329A ([(Z)-3-(4-Adamantan-2-yl-3,5-dichloro-phenyl)-allyl]-cyclohexyl-ethyl-amine) is a new ligand exhibiting high affinity for sigma(1) and sigma(2) receptors and for the human Delta8-Delta7-sterol isomerase. Here we show that this molecule ha
Autor:
Bernard Bourrie, Pierre Casellas, Estelle Bribes, Hubert Vidal, Martine Esclangon, Sylvaine Galiègue
Publikováno v:
European Journal of Pharmacology. 452:111-122
In this study, the effects of different peripheral benzodiazapine receptor ligands: PK 11195 [1-(2-chloro-phenyl)-N-methyl-N-(1-methylpropyl)-1-isoquinoline carboxamide], Ro5-4864 [7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin
Autor:
Pierre Casellas, Jean Marchand, Jean-Pierre Maffrand, Corinne Thomas, Laurent Garcia, Martine Esclangon, Estelle Bribes, Bernard Bourrie
Publikováno v:
Proceedings of the National Academy of Sciences. 96:12855-12859
Experimental autoimmune encephalomyelitis (EAE) is a T cell autoimmune disorder that is a widely used animal model for multiple sclerosis (MS) and, as in MS, clinical signs of EAE are associated with blood–brain barrier (BBB) disruption. SR 57746A,
Autor:
J.‐M. Benoît, Bernard Bourrie, P. Casellas, Jean-Marie Derocq, Martine Esclangon, G. Le Fur, C. Thomas
Sigma receptors originally described in distinct regions of the central nervous system are expressed on cells of the immune system. A sigma ligand, SR 31747A, was observed here to inhibit in vitro the Staphylococcal enterotoxin B (SEB)-driven lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f060619effba246e153704782f638b
https://europepmc.org/articles/PMC1456335/
https://europepmc.org/articles/PMC1456335/
Autor:
Pierre Casellas, Martine Esclangon, Jean-Marc Benoit, Jean-Marie Derocq, Monsif Bouaboula, Gérard Le Fur, Bernard Bourrie
Publikováno v:
European journal of immunology. 25(10)
SR 31747A is a new sigma ligand eliciting immunosuppressive and anti-inflammatory properties. Here, we show that SR 31747A greatly enhances lipopolysaccharide (LPS)-induced systemic release of interleukin (IL)-10, while it inhibits the secretion of t