Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martine Delchambre"'
Autor:
Opokua Ofori-Anyinam, Denise McKinney, Joe Cohen, Kent E. Kester, Carolyn A. Holland, Christian F. Ockenhouse, Gerald Voss, Jolie Palensky Beckey, D. Gray Heppner, Philippe Moris, W. Ripley Ballou, Martine Delchambre, Urszula Krzych, Nadia Tornieporth
Publikováno v:
Vaccine. 32:6683-6691
In an attempt to improve the efficacy of the candidate malaria vaccine RTS,S/AS02, two studies were conducted in 1999 in healthy volunteers of RTS,S/AS02 in combination with recombinant Plasmodium falciparum thrombospondin-related anonymous protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19d7caa2c280082b316e4bde692f8eb
https://doi.org/10.1016/j.vaccine.2014.06.033
https://doi.org/10.1016/j.vaccine.2014.06.033
Autor:
A. V. S. Hill, Gerald Voss, Katie L. Flanagan, C. Carton, Magdalena Plebanski, Joe Cohen, M. Koutsoukos, Ansar A. Pathan, Ajit Lalvani, Moncef M. GlaxoSmithKline Slaoui, Philippe Moris, Martine Delchambre, Roger H. Brookes, Kent E. Kester, Edwin A. M. Lee, C. Van Hoecke, William Ripley Ballou
The RTS,S/SBAS2 vaccine confers sterile protection against Plasmodium falciparum sporozoite challenge. The mechanisms underlying this are of great interest, yet little is known about the immune effector mechanisms induced by this vaccine. The immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42610645f64de65fb75b304f050c3f77
https://doi.org/10.1086/315074
https://doi.org/10.1086/315074
Simian immunodeficiency virus (SIV) gag-specific major histocompatibility complex (MHC)-restricted cytotoxic T-lymphocyte (CTL) activity was elicited in four out of six cynomolgus macaques after two immunizations with SIV gag recombinant vaccinia vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcd0d29808c400c86a5e75ab189ad87
https://doi.org/10.1097/00002030-199103000-00012
https://doi.org/10.1097/00002030-199103000-00012
Autor:
Joe Cohen, V. Ann Stewart, Gerald Voss, D. Gray Heppner, Douglas S. Walsh, Shannon McGrath, Martine Delchambre, Nathalie Garçon, James F. Cummings, Kent E. Kester
Publikováno v:
Vaccine. 24:6493-6502
Background Studies are underway to identify more immunogenic formulations of the existing anti-falciparum malaria vaccine RTS,S/AS02A. To supplement in vitro immunogenicity assays, cutaneous delayed-type hypersensitivity (DTH) may be a useful indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad092e2133b4396c62d50b35f1e2af5a
https://doi.org/10.1016/j.vaccine.2006.06.035
https://doi.org/10.1016/j.vaccine.2006.06.035
Autor:
Joe Cohen, Keith P. W. J. McAdam, Tom Doherty, William H. H. Reece, Martine Delchambre, Kent E. Kester, Brian Greenwood, Ali Alloueche, Paul Milligan, David J. Conway, Laurence Vigneron, Gerald Voss, Lawrence Yamuah, Margaret Pinder, Nadia Tornieporth, W. Ripley Ballou, Philip Gothard, Kalifa Bojang, Adrian V. S. Hill
Publikováno v:
The Lancet. 358:1927-1934
Summary Background RTS,S/AS02 is a pre-erythrocytic malaria vaccine based on the circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a new adjuvant (AS02). We did a randomised trial of the efficacy of RTS,S/AS02 ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c89b513c48983c84cdd7361e2195713
https://doi.org/10.1016/s0140-6736(01)06957-4
https://doi.org/10.1016/s0140-6736(01)06957-4
Autor:
Kent E, Kester, James F, Cummings, Christian F, Ockenhouse, Robin, Nielsen, B Ted, Hall, Daniel M, Gordon, Robert J, Schwenk, Urszula, Krzych, Carolyn A, Holland, Gregory, Richmond, Megan G, Dowler, Jackie, Williams, Robert A, Wirtz, Nadia, Tornieporth, Laurence, Vigneron, Martine, Delchambre, Marie-Ange, Demoitie, W Ripley, Ballou, Joe, Cohen, D Gray, Heppner, Steve, Fitzpatrick
Publikováno v:
Vaccine. 26(18)
Summary Background Immunization with RTS,S/AS02 consistently protects some vaccinees against malaria infection in experimental challenges and in field trials. A brief immunization schedule against falciparum malaria would be compatible with the Expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405ce9af65d86746e47c0aa3cbbda6fd
https://pubmed.ncbi.nlm.nih.gov/18387719
https://pubmed.ncbi.nlm.nih.gov/18387719
Autor:
W. Ripley Ballou, Ted Hall, Kent E. Kester, Megan Dowler, Christian F. Ockenhouse, Peifang Sun, Bruce T. Wellde, Robert A. Wirtz, Denise McKinney, Marie-Claude Dubois, Katherine White, Gerald Voss, Martine Delchambre, D. Gray Heppner, Urszula Krzych, Nadia Tornieporth, Megan A. O’Brien, Joe Cohen, Robert A. Gasser, Janet Wittes, Robert Schwenk
Publikováno v:
Vaccine. 25(29)
We conducted an open-label safety and immunogenicity bridging study that compared liquid and lyophilized formulations of the candidate malaria vaccine RTS,S formulated in AS02A in 34 healthy, malaria-naive adults at WRAIR. Volunteers received two dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdaf35d9bf8b2440fdb74a4b1e94769
https://pubmed.ncbi.nlm.nih.gov/17574311
https://pubmed.ncbi.nlm.nih.gov/17574311
Autor:
Joe Cohen, Shannon McGrath, Gerald Voss, Lisa A. Ware, V. Ann Stewart, D. Gray Heppner, Douglas S. Walsh, Kent E. Kester, James F. Cummings, Stacey Davis, Douglas B. Tang, J. Robert Burge, Aaron S. Hess, Martine Delchambre, Nathalie Garçon
Publikováno v:
Vaccine. 24(42-43)
RTS,S/AS02A, a pre-erythrocytic Plasmodium falciparum vaccine based upon the circumsporozoite protein, is the only vaccine demonstrated in field trials to confer partial protection against a range of malaria disease manifestations. Pre-clinical studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0881224292b9258fb8ffbb87bd59505
https://pubmed.ncbi.nlm.nih.gov/16904798
https://pubmed.ncbi.nlm.nih.gov/16904798
Autor:
D. Gray Heppner, James F. Cummings, Opokua Ofori-Anyinam, Christian F. Ockenhouse, Stewart V Ann, Carter L. Diggs, Kent E. Kester, Babita Mahajan, Lorraine Soisson, Evelina Angov, M Vanhandenhove, Dupeh R. Palmer, Jeffrey A. Lyon, Urszula Krzych, Nadia Tornieporth, Martine Delchambre, Joe Cohen
Publikováno v:
Vaccine. 24(15)
We report the first safety and immunogenicity trial of the Plasmodium falciparum malaria blood stage vaccine candidate, FMP1/AS02A consisting of the FMP1 antigen, an Escherichia coli-expressed His-tagged fusion protein from the 42 kDa C-terminal frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c84f3bf07bd9ad37da0b85999b3d58
https://pubmed.ncbi.nlm.nih.gov/16356603
https://pubmed.ncbi.nlm.nih.gov/16356603
Autor:
Megan Dowler, Gerald Voss, W. Ripley Ballou, Urszula Krzych, Christian F. Ockenhouse, Nadia Tornieporth, Joe Cohen, Denise McKinney, Martine Delchambre, Janet Wittes, Ted Hall, Kent E. Kester, D. Gray Heppner, Jolie Palensky
Publikováno v:
The Journal of infectious diseases. 183(4)
After initial successful evaluation of the circumsporozoite-based vaccine RTS,S/SBAS2, developed by SmithKline Beecham Biologicals with the Walter Reed Army Institute of Research, protective efficacy of several regimens against Plasmodium falciparum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b03e8beedc66659ada1ec93a17c8eb9
https://pubmed.ncbi.nlm.nih.gov/11170991
https://pubmed.ncbi.nlm.nih.gov/11170991