Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Martine Chatelut"'
Autor:
Jacques Izopet, Jacqueline Puel, Francis Boudet, Marcel Miedougé, Lionel Rostaing, Karine Sandres-Sauné, Martine Chatelut, François Malecaze, Michel Abbal, Jean-Michel Mansuy
Publikováno v:
Journal of Medical Virology. 66:571-575
Prospective nucleic acid tests were carried out for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) using the COBAS Amplicor HIV-1 and HCV tests (Roche Diagnostics, Meylan, France) on potential organ (n=113) and cornea (n=368) donors i
Autor:
Robert Salvayre, Thierry Levade, Nathalie Andrieu-Abadie, Nathalie Augé, Jean-Pierre Jaffrézou, Bruno Ségui, Martine Chatelut
Publikováno v:
Chemistry and Physics of Lipids. 102:167-178
The ubiquitous sphingophospholipid sphingomyelin (SM) can be hydrolysed in human cells to ceramide by different sphingomyelinases (SMases). These enzymes exert a dual role, enabling not only the turnover of membrane SM and the degradation of exogenou
Autor:
Martine Chatelut, Jean-Claude Thiers, Guy Laurent, Isabelle Escargueil-Blanc, Thierry Levade, Pieraggi Mt, Nathalie Augé, Anne Nègre-Salvayre, Nathalie Andrieu-Abadie, Isabelle Lajoie-Mazenc, Robert Salvayre, Jean-Pierre Jaffrézou, Isabelle Suc
Publikováno v:
Journal of Biological Chemistry. 273:12893-12900
Proliferation of vascular smooth muscle cells (SMC) is a hallmark in the pathogenesis of atherosclerotic lesions. Mildly oxidized low density lipoproteins (UV-oxLDL), which are mitogenic to cultured AG-08133A SMC, activate the sphingomyelin (SM)-cera
Autor:
Martine Chatelut, Thierry Levade, Jean-Pierre Basile, Isabelle Redonnet-Vernhet, Robert Salvayre
Publikováno v:
Biochemical and Molecular Medicine. 62:42-49
The molecular defects in the LIPA gene encoding the lysosomal acid lipase (LAL) were investigated in two unrelated patients affected with cholesteryl ester storage disease (CESD), an autosomal recessive disorder associated with LAL-deficient activity
Autor:
Marcel, Miédougé, Martine, Chatelut, Jean-Michel, Mansuy, Lionel, Rostaing, François, Malecaze, Karine, Sandres-Sauné, Francis, Boudet, Jacqueline, Puel, Michel, Abbal, Jacques, Izopet
Publikováno v:
Journal of medical virology. 66(4)
Prospective nucleic acid tests were carried out for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) using the COBAS Amplicor HIV-1 and HCV tests (Roche Diagnostics, Meylan, France) on potential organ (n=113) and cornea (n=368) donors i
Autor:
M C Vincent, Martine Chatelut, E Duchayne, S Roudani, C Demur, Robert Salvayre, Jean Tkaczuk, Jean Feunteun, Thierry Levade, Sylvie Caspar-Bauguil, Pieraggi Mt, Jean-Claude Thiers, P Laharrague, N Vacaresse, L Alibaud
Publikováno v:
Scandinavian journal of immunology. 48(6)
Human lymphocytes derived from the peripheral blood of a healthy woman were transfected with a plasmid carrying the simian virus 40 (SV40) large T antigen. The successfully transformed cells contained SV40 large T DNA and were negative for Epstein-Ba
Autor:
Pierre J. Courtoy, Michèle Leruth, Thierry Levade, Shimon Gatt, Klaus Harzer, Arie Dagan, Sergio Marchesini, Martine Chatelut, Robert Salvayre
Publikováno v:
FEBS letters. 426(1)
Since the generation upon cell stimulation of the second messenger ceramide has been reported to occur in an endosomal/lysosomal compartment, we investigated whether ceramide formed in the lysosomes can escape this compartment. The metabolic fate of
Autor:
Thierry Levade, Helen Christomanou, Masao Hiraiwa, Barbara C. Paton, Martine Chatelut, John S. O'Brien, Klaus Harzer
Publikováno v:
FEBS letters. 417(3)
In loading tests using galactosylceramide which had been labelled with tritium in the ceramide moiety, living skin fibroblast lines derived from the original prosaposin-deficient patients had a markedly reduced capacity to degrade galactosylceramide.
Autor:
Thierry Levade, Pieraggi Mt, Helen Christomanou, Jean Feunteun, Robert Salvayre, Klaus Harzer, Martine Chatelut, Jean-Claude Thiers, Barbara C. Paton, Jean-Pierre Basile, John S. O'Brien, Yasuo Kishimoto
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 262(1-2)
Skin fibroblasts from patients with Farber disease (acid ceramidase deficiency) and from two siblings of the only known family affected with prosaposin deficiency were transformed by transfection with a plasmid carrying the SV40 large T antigen. The
Autor:
Thierry Levade, Anthony H. Fensom, Jean-Pierre Basile, Robert Salvayre, Martine Chatelut, Klaus Harzer, Jean Feunteun
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 245(1)
Farber disease is an inborn lysosomal storage disorder characterized by accumulation of ceramide in the patient's tissues due to the deficient activity of acid ceramidase. Currently, confirmation of the diagnosis is performed in an extremely limited