Výsledky vyhledávání - "Martine Alhenc Gelas"

Akademický článek

Heparin-induced Thrombocytopenia Diagnosis: A Retrospective Study Comparing Heparin-induced Platelet Activation Test to 14C-serotonin Release Assay

Autor: Marie-Caroline Gonthier, Nicolas Gendron, Philippine Eloy, Marie-Charlotte Bourrienne, Martine Alhenc-Gelas, Claire Pouplard, Bernard Tardy, Jean Szymezak, Charles Burdet, Vasiliki Gkalea, Dorothée Faille, Nadine Ajzenberg

Publikováno v: TH Open, Vol 05, Iss 04, Pp e507-e512 (2021)

Laboratory confirmation of heparin-induced thrombocytopenia (HIT) is of crucial importance and remains challenging and relies on platelet functional assays highlighting the presence of heparin-dependent platelet-activating antibodies in patient serum

Externí odkaz: https://doaj.org/article/ff25504293a14558bfca2e13846fd5e7

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Akademický článek

Functional Flow Cytometric Assay for Reliable and Convenient Heparin-Induced Thrombocytopenia Diagnosis in Daily Practice

Autor: Brigitte Tardy-Poncet, Aurélie Montmartin, Michele Piot, Martine Alhenc-Gelas, Philippe Nguyen, Ismail Elalamy, Andreas Greinacher, Emmanuel De Maistre, Dominique Lasne, Marie-Hélène Horellou, Grégoire Le Gal, Thomas Lecompte, Bernard Tardy, on behalf of the GFHT-HIT Study Group

Publikováno v: Biomedicines, Vol 9, Iss 4, p 332 (2021)

Reliable laboratory diagnosis of heparin-induced thrombocytopenia (HIT) remains a major clinical concern. Immunoassays are highly sensitive, while confirmatory functional tests (based on heparin-dependent platelet activation) lack standardization. We

Externí odkaz: https://doaj.org/article/0f7d4c37a7524413ab6eeea32f79636f

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Akademický článek

Novel Splice Site Mutation in the PROS1 Gene in a Polish Patient with Venous Thromboembolism: c.602-2delA, Splice Acceptor Site of Exon 7

Autor: Magdalena Mrożek, Ewa Wypasek, Martine Alhenc-Gelas, Daniel P. Potaczek, Anetta Undas

Publikováno v: Medicina, Vol 56, Iss 9, p 485 (2020)

We identified a novel splice site mutation of the PROS1 gene in a Polish family with protein S (PS) deficiency and explored the molecular pathogenesis of this previously undescribed variant. A novel mutation was detected in a 26-year-old woman with a

Externí odkaz: https://doaj.org/article/192d275916c34800a038d42a8dd67858

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Heparin‐induced thrombocytopenia: Construction of a pretest diagnostic score derived from the analysis of a prospective multinational database, with internal validation

Publikováno v: Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, Wiley, 2021, 19 (8), pp.1959-1972. ⟨10.1111/jth.15344⟩
Journal of thrombosis and haemostasis, Vol. 19, no. 8, p. 1959-1972 (2021)
Journal of Thrombosis and Haemostasis, 2021, 19 (8), pp.1959-1972. ⟨10.1111/jth.15344⟩

International audience; Background Diagnosis of heparin-induced thrombocytopenia (HIT) requires pretest probability assessment and dedicated laboratory assays.Objective To develop a pretest score for HIT.Design Observational; analysis of prospectivel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7378cbe4040ab7ca498220c8e3d5807b
https://doi.org/10.1111/jth.15344

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Genotype–Phenotype Relationships in a Large French Cohort of Subjects with Inherited Protein C Deficiency

Autor: Laetitia Mauge, Geneviève Plu-Bureau, Isabelle Présot, Martine Alhenc-Gelas, Sophie Gandrille

Publikováno v: Thrombosis and Haemostasis. 120:1270-1281

Inherited protein C (PC) deficiency caused by mutations in the PROC gene is a well-known risk factor for venous thromboembolism. Few studies have investigated the relationship between PROC genotype and plasma or clinical phenotypes. We addressed this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12c08b504c04353793c10ab5aa0b7cc
https://doi.org/10.1055/s-0040-1714100

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Bilan de thrombophilie

Autor: Martine Alhenc-Gelas, Laetitia Mauge

Publikováno v: Revue Francophone des Laboratoires. 2020:26-33

Resume La liste des anomalies a rechercher dans le cadre du bilan de thrombophilie n’a pas change dans les dix dernieres annees, mais les evolutions technologiques et les resultats des travaux de recherche ont fait evoluer la place du genotypage da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ec8567feed67b9b6de888e0241ac0de
https://doi.org/10.1016/s1773-035x(20)30095-2

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