Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers

Autor: Françoise Derouane, Manon Desgres, Camilla Moroni, Jérôme Ambroise, Martine Berlière, Mieke R. Van Bockstal, Christine Galant, Cédric van Marcke, Marianela Vara-Messler, Stefan J. Hutten, Jos Jonkers, Larissa Mourao, Colinda L. G. J. Scheele, Francois P. Duhoux, Cyril Corbet

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-19 (2024)

Abstract Background Neoadjuvant chemotherapy (NAC) is the standard of care for patients with early-stage triple negative breast cancers (TNBC). However, more than half of TNBC patients do not achieve a pathological complete response (pCR) after NAC,

Externí odkaz: https://doaj.org/article/cbcb7ddcc69b4cbbb96f42be1600415c

Severe Gestational Gigantomastia: from Mastectomy to Staged Autologous Breast Reconstruction. A Case Report

Autor: Noureddine Hassayoune, MD, Mina Mhallem Gziri, MD, PhD, Audrey Lentini, MD, Theodoros Chrelias, MD, Jennifer Hammer, MD, Martine Berlière, MD, PhD, Benoît Lengelé, MD, PhD, FRCS, Maude Coyette, MD

Publikováno v: JPRAS Open, Vol 29, Iss , Pp 65-70 (2021)

Summary: Gestational gigantomastia (GGM) is a rare condition characterized by a massive overgrowth of breast tissue during pregnancy. Surgical sanction may be required when conservative measures fail. In this study, we report the case of a 29-year-ol

Externí odkaz: https://doaj.org/article/649fdbddf7db40e390f3400c1293d951

Abstract P4-07-16: B-IMMUNE final analysis: a phase Ib/II study of durvalumab combined with dose-dense EC in a neoadjuvant setting for patients with locally advanced luminal B HER2(-) or triple negative breast cancers

Autor: Alix Devaux, Gabriela Beniuga, Claire Quaghebeur, Stéphanie Henry, Mieke Van Bockstal, Christine Galant, Paul Delrée, Jean-Luc Canon, Brigitte Honhon, Dominique Korman, Vincent Verschaeve, Christophe Lonchay, Sarah Lefevre, Lionel D’Hondt, Martine Berlière, Sophie Delmarcelle, Jean-Michel Mine, Timour Willems, Gebhard Müller, Nathalie Myant, Isabelle Bar, Sandy Haussy, Pierre G. Coulie, François P. Duhoux, Javier Carrasco

Publikováno v: Cancer Research. 83:P4-07

Background: Neoadjuvant association of immune checkpoints inhibitors (ICI) and dose dense chemotherapy is promising for triple negative breast cancers (TNBC). However, response rates vary from one study to another. Timing, best chemotherapy partner a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b068f4919376854f308d00506f3390e5
https://doi.org/10.1158/1538-7445.sabcs22-p4-07-16

Severe Gestational Gigantomastia: from Mastectomy to Staged Autologous Breast Reconstruction. A Case Report

Autor: Jennifer Hammer, Theodoros Chrelias, Martine Berlière, Mina Mhallem Gziri, Benoît Lengelé, Noureddine Hassayoune, Audrey Lentini, Maude Coyette

Publikováno v: JPRAS Open
JPRAS open, Vol. 29, no.1, p. 65-70 (2021)
JPRAS Open, Vol 29, Iss, Pp 65-70 (2021)

Summary: Gestational gigantomastia (GGM) is a rare condition characterized by a massive overgrowth of breast tissue during pregnancy. Surgical sanction may be required when conservative measures fail. In this study, we report the case of a 29-year-ol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39d397fa36a2795955654908f0f1802
http://europepmc.org/articles/PMC8220097

Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations

Autor: Alberta Ferrari, Lucia Del Mastro, Albert Grinshpun, Amir Sonnenblick, Sileny Han, Matteo Lambertini, Philip D. Poorvu, Jose Alejandro Perez-Fidalgo, Fedro A. Peccatori, Rossella Graffeo, Riccardo Ponzone, Hatem A. Azim, Shani Paluch-Shimon, Luca Livraghi, Luis Augusto Teixeira, Olivier Caron, Maria Vittoria Dieci, Anne-Sophie Hamy, Michail Ignatiadis, Estela Carrasco, Laura De Marchis, Gianmaria Miolo, Claire Senechal, Martine Berlière, Christine Rousset-Jablonski, Katarzyna Pogoda, Octavi Cordoba, Cynthia Villarreal-Garza, Anna Zingarello, Helena Luna Pais, Laura Cortesi, Claire Saule, Lieveke Ameye, Florian Clatot, Maria Del Pilar Estevez-Diz, Marianne Paesmans, Ann H. Partridge

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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PURPOSE Young women with germline BRCA mutations have unique reproductive challenges. Pregnancy after breast cancer does not increase the risk of recurrence; however, very limited data are available in patients with BRCA mutations. This study investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798c1cd7dac3641a833e47552c1c1206
https://doi.org/10.1200/jco.19.02399