Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Martina Zemke"'
Autor:
Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The transcription factor Yin Yang 1 (YY1) plays an important role in human disease, yet little is known about its role in brain development. This study shows that YY1 controls cerebral cortex development by maintaining proliferation and survival of n
Externí odkaz:
https://doaj.org/article/bc26cd50490644df85c84964bd1b920a
Autor:
Raymond Hoffmans, Tomas Valenta, Claudio Cantù, Kalina Draganova, Magdalena Götz, Luis Zurkirchen, Konrad Basler, Martina Zemke, Michal J. Okoniewski, Marie-Theres Schmid, Lukas Sommer
Publikováno v:
Stem cells (Dayton Ohio)
Stem Cells 33, 170-182 (2015)
Stem Cells 33, 170-182 (2015)
The fate of neural progenitor cells (NPCs) is determined by a complex interplay of intrinsic programs and extrinsic signals, very few of which are known. β-Catenin transduces extracellular Wnt signals, but also maintains adherens junctions integrity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfc0760e7d5d5e574b793ea28fca3b2
Autor:
Lukas Sommer, Kalina Draganova, Kasum Azim, Martina Zemke, Arthur M. Butt, Bruno Fischer, Olivier Raineteau, Claudio Cantù, Anahi Hurtado-Chong
Publikováno v:
Stem cells (Dayton Ohio)
Azim, K, Fischer, B, Hurtado-Chong, A, Draganova, K, Cantu, C, Zemke, M, Sommer, L, Butt, A & Raineteau, O 2014, ' Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons ', Stem Cells, vol. 32, no. 5, pp. 1301-1312 . https://doi.org/10.1002/stem.1639
Azim, K, Fischer, B, Hurtado-Chong, A, Draganova, K, Cantu, C, Zemke, M, Sommer, L, Butt, A & Raineteau, O 2014, ' Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons ', Stem Cells, vol. 32, no. 5, pp. 1301-1312 . https://doi.org/10.1002/stem.1639
In the postnatal and adult central nervous system (CNS) the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs) the myelinating cells of the CNS. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18661ec644972871d712035b1e1597fe
https://doi.org/10.1002/stem.1639
https://doi.org/10.1002/stem.1639
Autor:
Martina Zemke, Kalina Draganova, Annika Klug, Anne Schöler, Luis Zurkirchen, Max Hans-Peter Gay, Phil Cheng, Haruhiko Koseki, Tomas Valenta, Dirk Schübeler, Konrad Basler, Lukas Sommer
Publikováno v:
BMC Biology
Background Precise spatiotemporal control of gene expression is essential for the establishment of correct cell numbers and identities during brain development. This process involves epigenetic control mechanisms, such as those mediated by the polyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137057f2ea8bdca9ae884a4ba14fbca2
https://doi.org/10.5167/uzh-115847
https://doi.org/10.5167/uzh-115847
Autor:
Anne Schöler, Kalina Draganova, Sandra Varum, Lukas Sommer, Dirk Schübeler, Daniel Schwarz, Arianna Baggiolini, Martina Zemke, Haruhiko Koseki
Publikováno v:
Development
Development (Cambridge England)
Development (Cambridge England)
The emergence of craniofacial skeletal elements, and of the jaw in particular, was a crucial step in the evolution of higher vertebrates. Most facial bones and cartilage are generated during embryonic development by cranial neural crest cells, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a454e6e4ca9e0ae26a5d596b7f9210
https://pubmed.ncbi.nlm.nih.gov/24496623
https://pubmed.ncbi.nlm.nih.gov/24496623
Autor:
Tomas Valenta, Max Gay, Sarah Steiner, Kalina Draganova, Martina Zemke, Raymond Hoffmans, Paolo Cinelli, Michel Aguet, Lukas Sommer, Konrad Basler
Publikováno v:
Genes & development
β-Catenin, apart from playing a cell-adhesive role, is a key nuclear effector of Wnt signaling. Based on activity assays in Drosophila, we generated mouse strains where the endogenous β-catenin protein is replaced by mutant forms, which retain the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd77ea7cb807bebe476db9e3982a776
https://pubmed.ncbi.nlm.nih.gov/22279043
https://pubmed.ncbi.nlm.nih.gov/22279043