Výsledky vyhledávání - "Martina Vojtechova"

Akademický článek

Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors

Autor: Jan Kriska, Lucie Janeckova, Denisa Kirdajova, Pavel Honsa, Tomas Knotek, David Dzamba, Denisa Kolenicova, Olena Butenko, Martina Vojtechova, Martin Capek, Zbynek Kozmik, Makoto Mark Taketo, Vladimir Korinek, Miroslava Anderova

Publikováno v: Frontiers in Neuroscience, Vol 15 (2021)

Modulating endogenous regenerative processes may represent a suitable treatment for central nervous system (CNS) injuries, such as stroke or trauma. Neural stem/progenitor cells (NS/PCs), which naturally reside in the subventricular zone (SVZ) of the

Externí odkaz: https://doaj.org/article/abcd8bb230064c7b80ad86ff6baa7608

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Akademický článek

HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy

Autor: Lucie Janeckova, Michal Kolar, Jiri Svec, Lucie Lanikova, Vendula Pospichalova, Nikol Baloghova, Martina Vojtechova, Eva Sloncova, Hynek Strnad, Vladimir Korinek

Publikováno v: Translational Oncology, Vol 9, Iss 2, Pp 99-107 (2016)

Neoplastic growth is frequently associated with genomic DNA methylation that causes transcriptional silencing of tumor suppressor genes. We used a collection of colorectal polyps and carcinomas in combination with bioinformatics analysis of large dat

Externí odkaz: https://doaj.org/article/9f1b1d985a2d49578ef07e9ef602a819

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Supplementary Figures S1-3, Tables S1-3 from HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage–Associated Tumorigenesis

Autor: Vladimir Korinek, Hynek Strnad, Katerina Galuskova, Eva Sloncova, Jitka Stancikova, Adela Hlavata, Monika Horazna, Nikol Baloghova, Dominique Leprince, Marion Dubuissez, Jan Dobes, Jolana Tureckova, Martina Vojtechova, Bohumil Fafilek, Vendula Pospichalova, Lucie Janeckova

Supplementary Figures S1-3, Tables S1-3. Supplementary Figure S1. Heatmaps depicting gene expression in Hic1flox/flox MEFs treated with 4- OHT when compared to MEFs treated with vehicle (ethanol) only. Genes (299 in total) displaying significantly (q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440d8b5f04d038210d2bc49664dc3652
https://doi.org/10.1158/1541-7786.22511505.v1

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Supplementary Materials and Methods, Figures 1 - 9, Tables 1 - 5 from Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice

Autor: Vladimir Korinek, Petr Bartunek, Zbynek Zdrahal, Jindrich Jindrich, Olga Machonova, Vitezslav Kriz, Monika Horazna, Eva Sloncova, Michaela Krausova, Dietmar Gradl, Jitka Stancikova, Martina Vojtechova, Antonio R. Pombinho, Lucie Tumova

PDF file - 515KB, Supplementary Materials and Methods. Supplementary Figure S1. Densitometric analysis of western blots shown in Figs. 2D (A), 3C (B) and 4D (C). Supplementary Figure S2. Monensin suppresses Wnt signaling activated by TALEN-induced di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8711be6e574a82a73568181fdd1f47d
https://doi.org/10.1158/1535-7163.22499776.v1

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Data from HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage–Associated Tumorigenesis

Hypermethylated in cancer 1 (HIC1) represents a prototypic tumor suppressor gene frequently inactivated by DNA methylation in many types of solid tumors. The gene encodes a sequence-specific transcriptional repressor controlling expression of several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::facf38d4d0dcc89d54095088de5ec890
https://doi.org/10.1158/1541-7786.c.6539961.v1

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Data from Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice

The Wnt signaling pathway is required during embryonic development and for the maintenance of homeostasis in adult tissues. However, aberrant activation of the pathway is implicated in a number of human disorders, including cancer of the gastrointest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0b5ad80d390450cfcc66779c4db350e
https://doi.org/10.1158/1535-7163.c.6536254

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Terminal differentiation of villus-tip enterocytes is governed by distinct members of Tgfβ superfamily

Autor: Linda Berková, Hassan Fazilaty, Qiutan Yang, Jan Kubovčiak, Monika Stastna, Dusan Hrckulak, Martina Vojtechova, Michael David Brügger, George Hausmann, Prisca Liberali, Vladimir Korinek, Konrad Basler, Tomas Valenta

The protective and absorptive functions of the intestinal epithelium rely on differentiated enterocytes in the villi. The differentiation of enterocytes is orchestrated by sub-epithelial mesenchymal cells producing distinct ligands along the villus a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df7c8f30efd9a1cdae49542f9dd09243
https://doi.org/10.1101/2022.11.11.516138

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Tumor suppressor Hypermethylated in Cancer 1 represses expression of cell cycle regulator E2F7 in human primary cells

Autor: Lucie Lanikova, Jiri Svec, Lucie Janeckova, Vendula Pospichalova, Nikol Dibus, Martina Vojtechova, Dusan Hrckulak, Eva Sloncova, Hynek Strnad, Vladimir Korinek

Hypermethylated in Cancer 1 (HIC1) is an established tumor suppressor, which is frequently inactivated in various cancers. In colorectal carcinoma (CRC), silencing of HIC1 has been recognized as one of the important events in malignant tumor progress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c48edb23fb7f520702879aa0f7f141a
https://doi.org/10.1101/2022.07.25.501405

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