Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Martina Vavra"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTMultidrug resistance poses global challenges, particularly with regard to Gram-negative bacterial infections. In view of the lack of new antibiotics, drug enhancers, such as efflux pump inhibitors (EPIs), have increasingly come into focus. A
Externí odkaz:
https://doaj.org/article/f6d2b66f471640b5acc42298e44ca6a8
Publikováno v:
Antibiotics, Vol 10, Iss 5, p 503 (2021)
In Escherichia coli, the role of RND-type drug transporters other than the major efflux pump AcrB has largely remained undeciphered (particularly in multidrug resistant pathogens), because genetic engineering in such isolates is challenging. The pres
Externí odkaz:
https://doaj.org/article/942dc45160f1442285971218e786706c
Publikováno v:
Molecules, Vol 24, Iss 3, p 470 (2019)
Phe-Arg-β-naphthylamide (PAβN) has been characterized as an efflux pump inhibitor (EPI) acting on the major multidrug resistance efflux transporters of Gram-negative bacteria, such as AcrB in Eschericha coli. In the present study, in vitro random m
Externí odkaz:
https://doaj.org/article/80953ceff0ff4f7f90b84035dfd681f4
Autor:
Anna M. Rohde, Sarah Walker, Michael Behnke, Simone Eisenbeis, Linda Falgenhauer, Jane C. Falgenhauer, Georg Häcker, Florian Hölzl, Can Imirzalioglu, Nadja Käding, Winfried V. Kern, Axel Kola, Evelyn Kramme, Alexander Mischnik, Silke Peter, Siegbert Rieg, Jan Rupp, Christian Schneider, Frank Schwab, Harald Seifert, Evelina Tacconelli, David Tobys, Janina Trauth, Anna Weber, Kyriaki Xanthopoulou, Janine Zweigner, Paul G. Higgins, Petra Gastmeier, Barisch Bader, Lena Biehl, Michael Buhl, Ariane Dinkelacker, Moritz Fritzenwanker, Hanna Gölz, Catriona Hennelly, Susanne Herold, Azita Lengler, Dana Lenke, Gabriele Peyerl-Hoffmann, Luis Alberto Peña Diaz, Georg Pilarski, Susanna Proske, Judith Schmiedel, Heike Spitznagel, Katrin Spohn, Norbert Thoma, Martina Vavra, Thorsten Wille, Maria J.G.T. Vehreschild
Publikováno v:
Clinical Microbiology and Infection. 29:515-522
Assessment of vancomycin-resistant Enterococcus faecium (VREfm) prevalence upon hospital admission and analysis of risk factors for colonization.From 2014 to 2018, patients were recruited within 72 hours of admission to seven participating German uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41155108c6aa4feed888e9fcade3e7ae
https://doi.org/10.1016/j.cmi.2022.11.025
https://doi.org/10.1016/j.cmi.2022.11.025
Publikováno v:
Microbial drug resistance (Larchmont, N.Y.). 28(12)
Efflux by resistance nodulation cell division transporters, such as AcrAB-TolC in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98ca5bf7c4f947237b1a175ae74bebd2
https://pubmed.ncbi.nlm.nih.gov/36255442
https://pubmed.ncbi.nlm.nih.gov/36255442
Autor:
Sandra Reuter, Tobias M. Schweigger, John W. A. Rossen, Martina Vavra, Sabine Schuster, Johannes Camp, Winfried V. Kern
Publikováno v:
Antimicrobial Agents and Chemotherapy, 65(4):ARTN e01735-20. AMER SOC MICROBIOLOGY
Antimicrob Agents Chemother
Antimicrob Agents Chemother
Gram-negative bacteria partly rely on efflux pumps to facilitate growth under stressful conditions and to increase resistance to a wide variety of commonly used drugs. In recent years, Escherichia coli sequence type 131 (ST131) has emerged as a major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d4b0091856e66d4dea04fc07fdf28e
https://doi.org/10.1128/aac.01735-20
https://doi.org/10.1128/aac.01735-20
Publikováno v:
Antimicrobial Agents and Chemotherapy, 65(2):ARTN e01803-20. AMER SOC MICROBIOLOGY
Inactivating tolC in multidrug-resistant Escherichia coli with differing sequence types and quinolone resistance-determining mutations reveals remarkably potentiated activity of the first-in-class topoisomerase inhibitors gepotidacin and zoliflodacin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe8b294e5486c27d006d8e93ccabaf4
https://doi.org/10.1128/aac.01803-20
https://doi.org/10.1128/aac.01803-20
Publikováno v:
Antimicrob Agents Chemother
Inactivating tolC in multidrug-resistant Escherichia coli with differing sequence types and quinolone resistance-determining mutations reveals remarkably potentiated activity of the first-in-class topoisomerase inhibitors gepotidacin and zoliflodacin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f01a7232b4e6ef9a3c1aca4dbfbbc7e
https://pubmed.ncbi.nlm.nih.gov/33199388
https://pubmed.ncbi.nlm.nih.gov/33199388
Autor:
Philipp M P, Baumert, Johannes, Camp, Hannah, Gölz, Martina, Vavra, Sabine, Schuster, Winfried V, Kern, Alexander, Mischnik, Thorsten, Wille
Publikováno v:
Microbial drug resistance (Larchmont, N.Y.). 26(6)
Objectives: This study aimed at determining the prevalence of rifaximin resistance in a large collection of Enterobacterales resistant to third-generation cephalosporins. A simple agar screen was d...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706db431a2827dc0b58af551be38a37e
https://pubmed.ncbi.nlm.nih.gov/31855490
https://pubmed.ncbi.nlm.nih.gov/31855490
Autor:
Robert Thimme, M. Büchsel, Winfried V. Kern, John W. A. Rossen, C. Pichler, Alexander Mischnik, Martina Vavra, Sandra Reuter
Publikováno v:
New Microbes and New Infections, Vol 17, Iss C, Pp 77-80 (2017)
New Microbes and New Infections, 17, 77-80
New Microbes and New Infections
New Microbes and New Infections, 17, 77-80
New Microbes and New Infections
We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d939c840735fb78d56c0b92ff1606e7