Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martina Uggè"'
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36499- (2024)
Heterochromatin is a pivotal element in the functional organization of genomes. In our study, we delve into the heterochromatin pattern of association by the PML (promyelocytic leukemia) protein. By using PML chromatin immunoprecipitation and sequenc
Externí odkaz:
https://doaj.org/article/dd93ecc788614873908272f1d059ade7
Autor:
Daniela Magliulo, Matilde Simoni, Carolina Caserta, Cristina Fracassi, Serena Belluschi, Kety Giannetti, Raffaella Pini, Ettore Zapparoli, Stefano Beretta, Martina Uggè, Eleonora Draghi, Federico Rossari, Nadia Coltella, Cristina Tresoldi, Marco J Morelli, Raffaella Di Micco, Bernhard Gentner, Luca Vago, Rosa Bernardi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-19 (2023)
Abstract One of the defining features of acute myeloid leukemia (AML) is an arrest of myeloid differentiation whose molecular determinants are still poorly defined. Pharmacological removal of the differentiation block contributes to the cure of acute
Externí odkaz:
https://doaj.org/article/2d1702404ed248f580d807aa7c1fabee
Publikováno v:
Trends in Biochemical Sciences. 47:609-619
PML is a stress-responsive protein that coordinates assembly of phase-separated nuclear aggregates, known as PML nuclear bodies (PML-NBs), where a large number of protein interactors and chromatin processes are finely regulated. Tampering with the PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16b7d494c1b5969590616d94316e9f0
https://doi.org/10.1016/j.tibs.2022.02.002
https://doi.org/10.1016/j.tibs.2022.02.002
Autor:
Anita, Lombardi, Lavinia, Arseni, Roberta, Carriero, Emmanuel, Compe, Elena, Botta, Debora, Ferri, Martina, Uggè, Giuseppe, Biamonti, Fiorenzo A, Peverali, Silvia, Bione, Donata, Orioli
Publikováno v:
Proc Natl Acad Sci U S A
The cancer-free photosensitive trichothiodystrophy (PS-TTD) and the cancer-prone xeroderma pigmentosum (XP) are rare monogenic disorders that can arise from mutations in the same genes, namely ERCC2/XPD or ERCC3/XPB. Both XPD and XPB proteins belong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::335a5f7eb05783df37a82472b3ef4b77
https://pubmed.ncbi.nlm.nih.gov/34155103
https://pubmed.ncbi.nlm.nih.gov/34155103
Autor:
Emmanuel Compe, Roberta Carriero, Anita Lombardi, Elena Botta, Martina Uggè, Silvia Bione, Lavinia Arseni, Giuseppe Biamonti, Donata Orioli, Fiorenzo A. Peverali, Debora Ferri
Publikováno v:
Proceedings of the National Academy of Sciences. 118
The cancer-free photosensitive trichothiodystrophy (PS-TTD) and the cancer-prone xeroderma pigmentosum (XP) are rare monogenic disorders that can arise from mutations in the same genes, namely ERCC2/XPD or ERCC3/XPB Both XPD and XPB proteins belong t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861916b43e50e2190ad46cfcd2ec61f2
https://doi.org/10.1073/pnas.2024502118
https://doi.org/10.1073/pnas.2024502118
Autor:
Marc Thill, Lourdes Calvo, Begoña Bermejo, Antonio Antón, Vladimir Semiglazov, Patrizia Zucchinelli, Jose Ignacio Chacon, Serafin Morales Murillo, Claudio Doglioni, Ainhara Lahuerta, Barbara Galbardi, Luca Gianni, Giampaolo Bianchini, Mauro Mansutti, Martina Uggè, Ignasi Tusquets, Pinuccia Valagussa, Isabel Alvarez, Arlene Chan, Chanel Smart, Isabella Sassi, R. Bernardi, Stefania Zambelli, Giancarlo Bisagni
Publikováno v:
Cancer Research. 80:P5-06
Background. Although long considered a tumor suppressor gene, PML (promyelocytic leukemia) also plays tumor-promoting functions in specific contexts. In vitro and in vivo studies have demonstrated that PML is upregulated by HIF-1α transcriptional ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c907688620e6e9e610c53b7e498a3e2
https://doi.org/10.1158/1538-7445.sabcs19-p5-06-21
https://doi.org/10.1158/1538-7445.sabcs19-p5-06-21
Autor:
Martina Uggè, Cristina Lecchi, Chiara Giudice, Paola Sartorelli, Alessio Scarafoni, Antonella Baldi
Publikováno v:
Veterinary journal (London, England : 1997). 203(3)
Adiponectin is an adipocyte-derived hormone, which circulates in the form of homo-multimers. The individual oligomers have a distinct profile of activity, playing crucial roles in several biological processes, including metabolism and inflammation. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b263d1262df5729fa1bd10dcde07d9fb
https://pubmed.ncbi.nlm.nih.gov/25900194
https://pubmed.ncbi.nlm.nih.gov/25900194