Výsledky vyhledávání - "Martina Tripari"

BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Autor: Sarah E. Barnett, Jenna Kenyani, Martina Tripari, Zohra Butt, Rudi Grosman, Francesca Querques, Liam Shaw, Luisa C. Silva, Zoe Goate, Stefan J. Marciniak, Doris M. Rassl, Richard Jackson, Lu-Yun Lian, Peter W. Szlosarek, Joseph J. Sacco, Judy M. Coulson

Publikováno v: Molecular Cancer Research. 21:411-427

The nuclear deubiquitylase BRCA1-associated protein 1 (BAP1) is frequently inactivated in malignant pleural mesothelioma (MPM) and germline BAP1 mutation predisposes to cancers including MPM. To explore the influence on cell physiology and drug sensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6bcdd5e6635a9317f5791b34b8bcc90
https://doi.org/10.1158/1541-7786.mcr-22-0635

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Data from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Autor: Judy M. Coulson, Joseph J. Sacco, Peter W. Szlosarek, Lu-Yun Lian, Richard Jackson, Doris M. Rassl, Stefan J. Marciniak, Zoe Goate, Luisa C. Silva, Liam Shaw, Francesca Querques, Rudi Grosman, Zohra Butt, Martina Tripari, Jenna Kenyani, Sarah E. Barnett

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f2a26145563ea502d969aa75f1b8c3
https://doi.org/10.1158/1541-7786.c.6545790

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Supplementary Table S4 from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Metabolomics MeT5A isogenics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144856d122196088283a2649bc5d6a7a
https://doi.org/10.1158/1541-7786.22725146

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Supplementary Methods and References from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Supplementary Methods, References and List of Figures and Tables

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf91e8fa62edb8842a191d49c5499d5
https://doi.org/10.1158/1541-7786.22528791

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Supplementary Table S3 from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Proteomics MeT5A isogenics and MPM cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c62cec5252a50ae2a9935899e61f39
https://doi.org/10.1158/1541-7786.22528779

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Supplementary Table S1 from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

STR profiling MPM cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59117cf8cce3d6e961574c213d34cd2c
https://doi.org/10.1158/1541-7786.22528788.v1

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Supplementary Figures S1 to S16 from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Fig. S1. SNP6.0 analysis of parental MeT5A-BAP1+/+ cells.Fig. S2. Expression of catalytically active BAP1 in parental MeT5A.Fig. S3. Characterisation of BAP1 expression in gene-edited MeT5A.Fig. S4. Whole genome sequencing of gene-edited MeT5A.Fig. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f6fcf22fd1f133b9edf46c65ca1fbe
https://doi.org/10.1158/1541-7786.22528794

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Supplementary Table S5 from BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

Patient scoring and survival summary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b7b01685cb6943b8083ce77f532289
https://doi.org/10.1158/1541-7786.22528773

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SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair

Autor: Stefano Percio, Alessandro Cicchetti, Monica Tortoreto, Valentina Zuco, C. Stucchi, Riccardo Valdagni, Nadia Zaffaroni, Paolo Gandellini, Martina Tripari, Valentina Doldi, Rihan El Bezawy, Stella Tinelli

Publikováno v: Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1462, p 1462 (2020)

Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is the most commonly mutated gene in prostate cancer (PCa). Recent evidence reports a role of SPOP in DNA damage response (DDR), indicating a possible impact of SPOP deregulation on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112957208663c061d3197dcdcfe38d1e

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