Výsledky vyhledávání - "Martina Svedova"

Akademický článek

Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.

Autor: Irena Adkins, Jana Kamanova, Aneta Kocourkova, Martina Svedova, Jakub Tomala, Hana Janova, Jiri Masin, Barbora Chladkova, Ladislav Bumba, Marek Kovar, Padraig J Ross, Ludmila Tuckova, Radek Spisek, Kingston H G Mills, Peter Sebo

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e104064 (2014)

Adenylate cyclase toxin (CyaA) is a key virulence factor of the whooping cough agent Bordetella pertussis. The toxin targets CD11b-expressing phagocytes and delivers into their cytosol an adenylyl cyclase (AC) enzyme that subverts cellular signaling

Externí odkaz: https://doaj.org/article/4e60af0e4ce6475bbe8900143a0c5749

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Pore‐formation by adenylate cyclase toxoid activates dendritic cells to prime CD8+and CD4+T cells

Autor: Marek Kovar, Jiri Masin, Peter Sebo, Irena Adkins, Martina Svedova, Ludmila Tučková, Marina A. Freudenberg, Jakub Tomala, Radovan Fišer, Gilles Dadaglio, Ondrej Cerny

Publikováno v: Immunology and Cell Biology
Immunology and Cell Biology, Nature Publishing Group, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩
Immunology and Cell Biology, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩

International audience; The adenylate cyclase toxin-hemolysin (CyaA) of Bordetella pertussis is a bi-functional leukotoxin. It penetrates myeloid phagocytes expressing the complement receptor 3 and delivers into their cytosol its N-terminal adenylate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7621bce15270defe1e4e243f36f86d
https://doi.org/10.1038/icb.2015.87

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Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis

Autor: Radim Osicka, Peter Sebo, Ivan Kanchev, Jakub Tomala, Barbora Tomalova, Pavel Rossmann, Ilona Bibova, Marek Kovar, Jiri Masin, Karolina Skopova, Radislav Sedlacek, Martina Svedova, Nicole Guiso, Irena Adkins

Publikováno v: Infection and Immunity. 85

The adenylate cyclase toxin-hemolysin (CyaA, ACT, or AC-Hly) of Bordetella pertussis targets phagocytic cells expressing the complement receptor 3 (CR3, Mac-1, α M β 2 integrin, or CD11b/CD18). CyaA delivers into cells an N-terminal adenylyl cyclas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4e9f60679e805b80e5b78bb7834272
https://doi.org/10.1128/iai.00937-16

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Bordetella Adenylate Cyclase Toxin Differentially Modulates Toll-Like Receptor-Stimulated Activation, Migration and T Cell Stimulatory Capacity of Dendritic Cells

Autor: Aneta Kocourkova, Hana Janova, Ludmila Tučková, Jana Kamanova, Marek Kovar, Jiri Masin, Ladislav Bumba, Kingston H. G. Mills, Martina Svedova, Pádraig J. Ross, Barbora Chladkova, Radek Spisek, Irena Adkins, Jakub Tomala, Peter Sebo

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e104064 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e9ae3ca14f39bb257062eb3512620b
http://europepmc.org/articles/PMC4118975

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Effect on the immune system of germ-free piglets of probiotics potentiated with polyunsaturated fatty acids

Autor: Rudolf, Kastel, Alojz, Bomba, Robert, Herich, Ladislav, Vasko, Martina, Svedova

Publikováno v: Berliner und Munchener tierarztliche Wochenschrift. 120(5-6)

The present study investigated the influence of polyunsaturated fatty acids (PUFA) on the immune system of germ-free piglets. Oil with increased content of omega-3 PUFA was administered to piglets from the experimental group (EG) for four weeks. Pigl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::915ea0f3c228396ad29706bdc99e6772
https://pubmed.ncbi.nlm.nih.gov/17555043

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