Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martina Stalder"'
Autor:
Sonia Boncristiano, Martina Stalder, Esther Kohler, Mathias Jucker, Matthias Staufenbiel, Michelle Pfeifer, Melanie Meyer-Luehmann, Dorothee Abramowski, Paul M. Mathews, Martin C. Herzig, Stephan A. Kaeser, Marc Mercken
Publikováno v:
Nature Neuroscience. 6:370-377
Amyloid precursor protein (APP) processing and the generation of beta-amyloid peptide (Abeta) are important in the pathogenesis of Alzheimer's disease. Although this has been studied extensively at the molecular and cellular levels, much less is know
Autor:
Luca Bondolfi, Michelle Pfeifer, Peter H. Kelly, Martina Stalder, Sonia Boncristiano, Mathias Jucker, Michael E. Calhoun, Matthias Staufenbiel, Amie L. Phinney, Bernd Sommer, Dorothee Abramowski, Albert Enz, Christine Sturchler-Pierrat
Publikováno v:
The Journal of Neuroscience. 22:3234-3243
Alzheimer's Disease (AD) is a neurodegenerative disorder that is characterized by extracellular deposits of amyloid-beta peptide (Abeta) and a severe depletion of the cholinergic system, although the relationship between these two events is poorly un
Publikováno v:
Neurobiology of Aging. 22:427-434
Microglia cells are closely associated with compact amyloid plaques in Alzheimer's disease (AD) brains. Although activated microglia seem to play a central role in the pathogenesis of AD, mechanisms of microglial activation by beta-amyloid as well as
Autor:
Rita Gerardy-Schahn, Natalie Hackel, Melitta Schachner, Martina Stalder, Thomas Schuster, Manfred Krug
Publikováno v:
Journal of Neurobiology. 49:142-158
We have investigated the possibility that morphologically different excitatory glutamatergic synapses of the "trisynaptic circuit" in the adult rodent hippocampus, which display different types of long-term potentiation (LTP), may express the immunog
Autor:
Matthias Staufenbiel, Bernd Sommer, Amie L. Phinney, Martina Stalder, Alphonse Probst, Mathias Jucker
Publikováno v:
The American Journal of Pathology. 154:1673-1684
Microglia are a key component of the inflammatory response in the brain and are associated with senile plaques in Alzheimer's disease (AD). Although there is evidence that microglial activation is important for the pathogenesis of AD, the role of mic
Autor:
Matthias Staufenbiel, Bernd Sommer, Karl-Heinz Wiederhold, Chantal Pauli, Lisa Schnell, Mathias Jucker, T. Martina Stalder, Florian Ermini, Klaus D. Bornemann
Publikováno v:
The American journal of pathology. 158(1)
A microglial response is part of the inflammatory processes in Alzheimer’s disease (AD). We have used APP23 transgenic mice overexpressing human amyloid precursor protein with the Swedish mutation to characterize this microglia response to amyloid
Autor:
Martina Stalder, Christine Sturchler-Pierrat, Sonia Boncristiano, Michelle Pfeifer, M C Herzig, Luca Bondolfi, A. Probst, Matthias Staufenbiel, M. E. Calhoun, David T. Winkler, Thomas Deller, A. Phinney, M Tolnay, Mathias Jucker, Karl-Heinz Wiederhold, Bernd Sommer, Dorothee Abramowski
Publikováno v:
Neurodegenerative Disorders: Loss of Function Through Gain of Function ISBN: 9783642074486
Transgenic mice that overexpress mutant human amyloid precursor protein (APP) exhibit one hallmark of Alzheimer’s disease pathology, namely the extracellular deposition of amyloid in plaques and vessels. In an effort to study the impact of cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d55ca4998561003987bec07afd1276
https://doi.org/10.1007/978-3-662-04399-8_6
https://doi.org/10.1007/978-3-662-04399-8_6
Autor:
Patrick Burgermeister, Martina Stalder, Christine Sturchler-Pierrat, Michael E. Calhoun, Bernd Sommer, Dorothee Abramowski, Mathias Jucker, Matthias Staufenbiel, Markus Tolnay, Karl-Heinz Wiederhold, Amie L. Phinney
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(24)
Transgenic mice that overexpress mutant human amyloid precursor protein (APP) exhibit one hallmark of Alzheimer’s disease pathology, namely the extracellular deposition of amyloid plaques. Here, we describe significant deposition of amyloid β (Aβ
Autor:
Bernd Sommer, Martina Stalder, Mathias Jucker, Michael E. Calhoun, Michael Frotscher, Thomas Deller, Amie L. Phinney, Matthias Staufenbiel
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(19)
A characteristic feature of Alzheimer’s disease (AD) is the formation of amyloid plaques in the brain. Although this hallmark pathology has been well described, the biological effects of plaques are poorly understood. To study the effect of amyloid
Autor:
Matthias Staufenbiel, Florian Ermini, Christine Sturchler-Pierrat, Klaus D. Bornemann, Mathias Jucker, Martina Stalder
Publikováno v:
Neurobiology of Aging. 21:227