Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Martina Seiffert"'
Autor:
Tereza Faitova, Mariana Coelho, Caspar da Cunha-Bang, Selcen Ozturk, Ece Kartal, Peer Bork, Martina Seiffert, Carsten U. Niemann
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
The gut microbiota play a critical role in maintaining a healthy human body and their dysregulation is associated with various diseases. In this study, we investigated the influence of the gut microbiome diversity on chronic lymphocytic leukemia (CLL
Externí odkaz:
https://doaj.org/article/4035c012d7a9418fb76f8315d98a3d3f
Autor:
John K. L. Wong, Lena Jassowicz, Christel Herold-Mende, Martina Seiffert, Jan-Philipp Mallm, Peter Lichter, Marc Zapatka
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-6 (2023)
Abstract Background Here we present scSNPdemux, a sample demultiplexing pipeline for single-cell RNA sequencing data using natural genetic variations in humans. The pipeline requires alignment files from Cell Ranger (10× Genomics), a population SNP
Externí odkaz:
https://doaj.org/article/f552b0897e864f92bec52c1fbb48ac58
Autor:
Giulia Pagano, Iria Fernandez Botana, Marina Wierz, Philipp M. Roessner, Nikolaos Ioannou, Xiangda Zhou, Gheed Al-Hity, Coralie Borne, Ernesto Gargiulo, Susanne Gonder, Bin Qu, Basile Stamatopoulos, Alan G. Ramsay, Martina Seiffert, Anne Largeot, Etienne Moussay, Jerome Paggetti
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Chronic lymphocytic leukemia (CLL) cells are highly dependent on interactions with the immunosuppressive tumor microenvironment (TME) for survival and proliferation. In the search for novel treatments, pro-inflammatory cytokines have emerged as candi
Externí odkaz:
https://doaj.org/article/f29683a86d924b2e8fdf058bdcf1c6eb
Autor:
Martina Seiffert
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/59db1fade0ae43a6ae915447b15b05ac
Autor:
Sebastian Faehling, Mariana Coelho, Alessia Floerchinger, Christof Schneider, Stephan Stilgenbauer, Peter Lichter, Martina Seiffert, Philipp M. Roessner
Publikováno v:
HemaSphere, Vol 7, Iss 3, p e840 (2023)
Chronic lymphocytic leukemia (CLL) is a common and incurable B-cell malignancy. Recent therapeutic approaches that target the B-cell receptor signaling pathway include inhibition of phosphatidylinositol-3-kinase (PI3K). The PI3K isoform delta is cons
Externí odkaz:
https://doaj.org/article/e31f1ca7f2774fc2bea8e1bd8ee35adf
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/18ca2433f6c042628cc41ba7e1aca56d
Autor:
Justyna A. Wierzbinska, Reka Toth, Naveed Ishaque, Karsten Rippe, Jan-Philipp Mallm, Lara C. Klett, Daniel Mertens, Thorsten Zenz, Thomas Hielscher, Marc Seifert, Ralf Küppers, Yassen Assenov, Pavlo Lutsik, Stephan Stilgenbauer, Philipp M. Roessner, Martina Seiffert, John Byrd, Christopher C. Oakes, Christoph Plass, Daniel B. Lipka
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-19 (2020)
Abstract Background In cancer, normal epigenetic patterns are disturbed and contribute to gene expression changes, disease onset, and progression. The cancer epigenome is composed of the epigenetic patterns present in the tumor-initiating cell at the
Externí odkaz:
https://doaj.org/article/07bff21ec86d48ca9abc2144570ae521
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/637e3811cfd2448eb39c318f5ed142e4
Autor:
Lavinia Arseni, Rakesh Sharma, Norman Mack, Deepthi Nagalla, Sibylle Ohl, Thomas Hielscher, Mahak Singhal, Robert Pilz, Hellmut Augustin, Roger Sandhoff, Christel Herold-Mende, Björn Tews, Peter Lichter, Martina Seiffert
Publikováno v:
Cancers, Vol 15, Iss 2, p 479 (2023)
Glioblastoma is the most aggressive brain tumor in adults. Treatment failure is predominantly caused by its high invasiveness and its ability to induce a supportive microenvironment. As part of this, a major role for tumor-associated macrophages/micr
Externí odkaz:
https://doaj.org/article/1b69a2706d904c5badfd21cf6ae2683b
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/da8050034163470f9e313823ffaf5896