Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Martina Schüßler-Lenz"'
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 9, Pp 1183-1197 (2017)
Abstract Chimeric antigen receptor (CAR) T cell therapy, together with checkpoint inhibition, has been celebrated as a breakthrough technology due to the substantial benefit observed in clinical trials with patients suffering from relapsed or refract
Externí odkaz:
https://doaj.org/article/c46fe4bcd57d451ab6caf467667d4401
Autor:
Elizabeth Fox, Michael Berntgen, Alfonso Quintás-Cardama, Veronique Minard-Colin, Susan L. Weiner, André Baruchel, Laura Pearce, Karsten Nysom, Andrew D.J. Pearson, Danielle H. Taylor, Christian M. Zwaan, Nirali N. Shah, Yousif Matloub, Ivan D. Horak, Gregory H. Reaman, Gilles Vassal, Koen Norga, Claudia Rossig, Dominik Karres, Lori A. Ehrlich, Martina Schüßler-Lenz, Alberto S. Pappo, Joe McDonough, Martina A. Sersch, Nick Richardson, Donna Ludwinski, Abraham Bassan, Eric Bleickardt, Nicole Scobie, Stephen Gottschalk, Rob Pieters, Sarah K. Tasian, Courtney Johnson, Teresa de Rojas, Malcolm A. Smith, Franca Ligas, Lynley V. Marshall, Shannon L. Maude, Brenda J. Weigel, Nick Bird, Najat Bouchkouj, Behzad K. Masouleh, Sarah Beaussant Cohen, Delphine Heenen, Rosanna Ricafort, G. Lesa, Linda Hanssens, Peter F. Bross, Carrie Brownstein, Crystal L. Mackall, Martin Pule, Douglas S. Hawkins, Jaroslav Sterba, Maksim Mamonkin
Publikováno v:
European Journal of Cancer. 160:112-133
The seventh multi-stakeholder Paediatric Strategy Forum focused on chimeric antigen receptor (CAR) T-cells for children and adolescents with cancer. The development of CAR T-cells for patients with haematological malignancies, especially B-cell precu
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ZusammenfassungKombinationstherapien von unterschiedlichen Arzneimitteln sind fester Bestandteil der Medizin. Wissenschaftlich und regulatorisch gilt jedoch der Anspruch, den Beitrag jedes Arzneimittels zum Gesamteffekt zu verstehen. Deshalb müssen
Autor:
Martina Schüssler-Lenz
Publikováno v:
Cell and Gene Therapy Insights. 6:1127-1134
Autor:
Andrew Dj, Pearson, Claudia, Rossig, Crystal, Mackall, Nirali N, Shah, Andre, Baruchel, Gregory, Reaman, Rosanna, Ricafort, Delphine, Heenen, Abraham, Bassan, Michael, Berntgen, Nick, Bird, Eric, Bleickardt, Najat, Bouchkouj, Peter, Bross, Carrie, Brownstein, Sarah Beaussant, Cohen, Teresa, de Rojas, Lori, Ehrlich, Elizabeth, Fox, Stephen, Gottschalk, Linda, Hanssens, Douglas S, Hawkins, Ivan D, Horak, Danielle H, Taylor, Courtney, Johnson, Dominik, Karres, Franca, Ligas, Donna, Ludwinski, Maksim, Mamonkin, Lynley, Marshall, Behzad K, Masouleh, Yousif, Matloub, Shannon, Maude, Joe, McDonough, Veronique, Minard-Colin, Koen, Norga, Karsten, Nysom, Alberto, Pappo, Laura, Pearce, Rob, Pieters, Martin, Pule, Alfonso, Quintás-Cardama, Nick, Richardson, Martina, Schüßler-Lenz, Nicole, Scobie, Martina A, Sersch, Malcolm A, Smith, Jaroslav, Sterba, Sarah K, Tasian, Brenda, Weigel, Susan L, Weiner, Christian Michel, Zwaan, Giovanni, Lesa, Gilles, Vassal
Publikováno v:
European journal of cancer
European journal of cancer, 160:112-133
European journal of cancer, 160:112-133
The seventh multi-stakeholder Paediatric Strategy Forum focused on chimeric antigen receptor (CAR) T-cells for children and adolescents with cancer. The development of CAR T-cells for patients with haematological malignancies, especially B-cell precu
Autor:
Michael Bachmann, Stefan B. Eichmüller, Matthias Renner, Gerald Willimsky, Brigitte Anliker, Winfried S. Wels, Michael Schmitt, Angela M. Krackhardt, Martina Schüssler-Lenz, Dirk M. Nettelbeck, Martin Hildebrandt, Lutz Uharek
Publikováno v:
Cancer Immunology, Immunotherapy. 67:513-523
Adoptive transfer of T cells genetically modified by TCRs or CARs represents a highly attractive novel therapeutic strategy to treat malignant diseases. Various approaches for the development of such gene therapy medicinal products (GTMPs) have been
Autor:
Lisbeth, Barkholt, Caroline, Voltz-Girolt, June, Raine, Tomas, Salmonson, Martina, Schüssler-Lenz
Publikováno v:
Nature reviews. Drug discovery. 18(1)
Publikováno v:
Trends in biotechnology. 37(2)
Medicinal products based on genome editing must undergo rigorous preclinical testing and are subject to regulatory oversight for proper risk assessment prior to first evaluation in humans. We give a European perspective on the regulatory expectations
Publikováno v:
Deutsches Ärzteblatt Online.
Autor:
Pieter A. Doevendans, Veronika Jekerle, Claire Beuneu, Romaldas Mačiulaitis, Jonathan Hill, Paula Salmikangas, Stefan Jovinge, Metoda Lipnik-Stangelj, Olli Tenhunen, Marit Hystad, Giuseppe Rosano, Jan Kyselovic, Anthony Samuel, Patrick Celis, Krishna Prasad, Maura O'Donovan, Andreas M. Zeiher, Jozef Bartunek, Margarida Menezes-Ferreira, Torsten Tonn, Steven A. J. Chamuleau, Martina Schüssler-Lenz
Publikováno v:
European Journal of Heart Failure. 18:133-141
In the past decade, novel cell-based products have been studied in patients with acute and chronic cardiac disease to assess whether these therapies are efficacious in improving heart function and preventing the development of end-stage heart failure