Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Martina S. McDermott"'
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5293c1f2b98c387442f19c7277b03110
https://doi.org/10.1158/0008-5472.22400151.v1
https://doi.org/10.1158/0008-5472.22400151.v1
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Fig. S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a09398a40aabf423b9e86b3834e3b4
https://doi.org/10.1158/0008-5472.22400166.v1
https://doi.org/10.1158/0008-5472.22400166.v1
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Fig. S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d82f1e0ad1409f0447e60cf799846d
https://doi.org/10.1158/0008-5472.22400157
https://doi.org/10.1158/0008-5472.22400157
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Material & Suppl. Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192dc31115bc0bae4709ee2006e1170a
https://doi.org/10.1158/0008-5472.22400154
https://doi.org/10.1158/0008-5472.22400154
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Fig. S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333d238324e04e10da217631241ca403
https://doi.org/10.1158/0008-5472.22400163
https://doi.org/10.1158/0008-5472.22400163
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Fig. S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4308569a6921ce887a6e179b9b90bf3e
https://doi.org/10.1158/0008-5472.22400160.v1
https://doi.org/10.1158/0008-5472.22400160.v1
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Intrinsic and acquired resistance to HER-targeting drugs occurs in a significant proportion of HER2-overexpressing breast cancers. Thus, there remains a need to identify predictive biomarkers that could improve patient selection and circumvent these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fb3e6daf7b5417bc44f37d65ce3c8b
https://doi.org/10.1158/0008-5472.c.6505512
https://doi.org/10.1158/0008-5472.c.6505512
Autor:
Tristin E. Rose, Brendan M. O'Boyle, Justin A. Hilf, Emma L. Baker-Tripp, Zhengao Feng, Kevin Yang, Michael D. Bartberger, Oliver C. Losón, Neil A. O'Brien, Martina S. McDermott, Naeimeh Kamranpour, Weiping Jia, Tong Luo, Raul Ayala, John Glasby, Brian M. Stoltz, Dennis J. Slamon
Publikováno v:
Cancer Research. 83:6258-6258
Small molecule inhibitors of KRASG12C have garnered substantial interest as a targeted therapy for lung, colon and pancreatic cancers bearing this mutation. Data from multiple clinical programs have shown strong efficacy in lung tumors but diminished
Autor:
Neil A. O'Brien, Martina S. McDermott, Brendan M. O'Boyle, Corey M. Reeves, Michael Bartberger, Oliver Loson, Kevin Chau, Jenny J. Hong, Weiping Jia, Naeimeh Kamranpour, Tong Luo, Raul Ayala, Athena M. Madrid, John A. Glaspy, Brian M. Stoltz, Dennis J. Slamon
Publikováno v:
Cancer Research. 83:4044-4044
The MAPK signaling pathway is the most commonly mutated and/or dysregulated pathway in cancer. Strategies to target it have yielded some success with inhibitors against KRASG12C and BRAF, and to a lesser extent, MEK1/2. However, the impact of these m
Autor:
Martina S. McDermott, Neil A. O'Brien, Brendan O'Boyle, Michael Bartberger, Oliver C. Losón, Kevin Chau, Ella Schwab, Jenny Hong, Jiaying Zhou, Chuhong Hu, Tong Luo, Raul Ayala, John Glasby, Brian M. Stoltz, Dennis J. Slamon
Publikováno v:
Cancer Research. 83:6254-6254
Protein arginine methyltransferase 5 (PRMT5) is a methyltransferase enzyme that symmetrically dimethylates arginine residues of histones, transcription elongation factors, translation regulators, and transcription factors like p53. It also regulates