Výsledky vyhledávání - "Martina Rump"

Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation

Autor: Alexander Novotny, Bernhard Holzmann, Peter F. Mühlradt, Martina Rump, Carolin Feterowski, Tanja Roßmann-Bloeck, Heike Weighardt, Simone Kaiser-Moore

Publikováno v: International Immunology. 17:1035-1046

The innate immune system uses Toll-like receptors (TLRs) to activate and instruct immune responses against microbial pathogens. Administration of TLR agonists to mice induces a state of hyporesponsiveness, or tolerance, characterized by reduced cytok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3950c843f1badca2536e32449b1ad7f
https://doi.org/10.1093/intimm/dxh282

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Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis

Autor: Bernhard Holzmann, Thomas Miethke, Martina Rump, Carolin Feterowski, Klaus Emmanuilidis, Kurt Ulm, Heike Weighardt, Klaus Gerauer

Publikováno v: Immunology. 109:426-431

Genetically determined responsiveness to microbial stimuli such as lipopolysaccharide (LPS) may affect the pathophysiology of human sepsis. The D299G mutation in human Toll-like receptor-4 (TLR4) impairs LPS signalling in homozygous and heterozygous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7640fef75d4abca820460f0f86e41c
https://doi.org/10.1046/j.1365-2567.2003.01674.x

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Increased Resistance Against Acute Polymicrobial Sepsis in Mice Challenged with Immunostimulatory CpG Oligodeoxynucleotides Is Related to an Enhanced Innate Effector Cell Response

Autor: Martina Rump, Carolin Feterowski, Martin Veit, Bernhard Holzmann, Heike Weighardt, Hermann Wagner

Publikováno v: The Journal of Immunology. 165:4537-4543

Recent reports support the concept that the major defect in polymicrobial sepsis is an impaired immunologic response to infection. Oligodeoxynucleotides containing CpG sequence motifs (CpG-ODN) were previously shown to induce immune protection in mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5b5613c094551802de35b94ffa2bd2
https://doi.org/10.4049/jimmunol.165.8.4537

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Akademický článek

Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation.

Autor: Carolin Feterowski, Alexander Novotny, Simone Kaiser-Moore, Peter F. Mhlradt, Tanja Romann-Bloeck, Martina Rump, Bernhard Holzmann, Heike Weighardt

Publikováno v: International Immunology; Aug2005, Vol. 17 Issue 8, p1035-1046, 12p

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