Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Martina Pfeffer"'
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1482 (2023)
In modern society, the time and duration of sleep on workdays are primarily determined by external factors, e.g., the alarm clock. This can lead to a misalignment of the intrinsically determined sleep timing, which is dependent on the individual chro
Externí odkaz:
https://doaj.org/article/28f609a7a5bd4eecb3eb3505edb48271
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The melatoninergic system comprises the neurohormone melatonin and its molecular targets. The major source of melatonin is the pineal organ where melatonin is rhythmically produced during darkness. In mammals, melatonin biosynthesis is controlled by
Externí odkaz:
https://doaj.org/article/75afa5c7b6694859aa67b2452de3a73e
Autor:
Amira A. H. Ali, Federica Tundo-Lavalle, Soha A. Hassan, Martina Pfeffer, Anna Stahr, Charlotte von Gall
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1394 (2020)
The circadian system is an endogenous timekeeping system that synchronizes physiology and behavior with the 24 h solar day. Mice with total deletion of the core circadian clock gene Bmal1 show circadian arrhythmicity, cognitive deficits, and accelera
Externí odkaz:
https://doaj.org/article/f0a906bb7f1e4b7897010e7a0f5421be
Autor:
Miriam Stenzinger, Darja Karpova, Christian Unterrainer, Sabine Harenkamp, Eliza Wiercinska, Keven Hoerster, Martina Pfeffer, Erik Maronde, Halvard Bonig
Publikováno v:
Cells, Vol 8, Iss 9, p 1033 (2019)
Circadian oscillations in circulating leukocyte subsets including immature hematopoietic cells have been appreciated; the origin and nature of these alterations remain elusive. Our analysis of wild-type C57BL/6 mice under constant darkness confirmed
Externí odkaz:
https://doaj.org/article/ab8810ae0efe4da1bf77f8c66859d32a
Autor:
Martina Pfeffer, Zuzana Zimmermann, Suzana Gispert, Georg Auburger, Horst-Werner Korf, Charlotte von Gall
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1651 (2018)
Parkinson’s disease (PD) is characterized by distinct motor and non-motor symptoms. Sleep disorders are the most frequent and challenging non-motor symptoms in PD patients, and there is growing evidence that they are a consequence of disruptions wi
Externí odkaz:
https://doaj.org/article/45434b02f6a746dcb2e22fb12bc6b47a
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 3, p 530 (2017)
The role of endogenous melatonin for the control of the circadian system under entrained conditions and for the determination of the chronotype is still poorly understood. Mice with deletions in the melatoninergic system (melatonin deficiency or the
Externí odkaz:
https://doaj.org/article/732d04e4816840a9ae715801481fb564
BACKGROUND In modern society, the midpoint and duration of sleep on workdays are primarily determined by the alarm clock. Early work, especially in late chronotypes, can lead to sleep timing misalignment and reduced sleep quality on workdays. This mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30274b60872c930ed43f5fc0b58012aa
https://doi.org/10.2196/preprints.46361
https://doi.org/10.2196/preprints.46361
Autor:
Horst-Werner Korf, Robert Brunkhorst, Josef Pfeilschifter, Waltraud Pfeilschifter, Martina Pfeffer, Dominique Thomas, Sandra Trautmann, Alexander Koch, Natasa Rajkovic, Christina Christoffersen, Claudia Fischer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1864:304-311
Key homeostatic functions are regulated in a diurnal manner and a miss-alignment of such rhythms is believed to contribute to the pathophysiology of several diseases. Signaling sphingolipids (SLs) in plasma such as sphingosine 1-phosphate control lym
Autor:
Dennis Sohn, Soha A Hassan, Amira A. H. Ali, Martina Pfeffer, Charlotte von Gall, Horst-Werner Korf, Reiner U. Jänicke, Mona Yassine
Publikováno v:
Journal of Pineal Research. 70
Cancer-related fatigue (CRF) and stress are common symptoms in cancer patients and represent early side effects of cancer treatment which affect the life quality of the patients. CRF may partly depend on disruption of the circadian rhythm. Locomotor
Publikováno v:
Journal of biological rhythms. 35(1)
Locomotor activity patterns of laboratory mice are widely used to analyze circadian mechanisms, but most investigations have been performed under standardized laboratory conditions. Outdoors, animals are exposed to daily changes in photoperiod and ot