Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martina Pavlová"'
Publikováno v:
Diagnostics, Vol 11, Iss 4, p 693 (2021)
Idiopathic interstitial pneumonia (IIP) entails a variable group of lung diseases of unknown etiology. Idiopathic pulmonary fibrosis, nonspecific interstitial pneumonia, interstitial lung diseases related to connective tissue disease (CTD-ILD), and h
Externí odkaz:
https://doaj.org/article/983b3b2376d5418ead04d0a12dd3a6d9
Autor:
Dick B. Janssen, Martina Pavlová, M. Irfan Arif, Jiri Damborsky, Christiaan P. Postema, Ghufrana Samin
Publikováno v:
Applied and environmental microbiology, 80(17), 5467-5476. AMER SOC MICROBIOLOGY
1,2,3-Trichloropropane (TCP) is a toxic compound that is recalcitrant to biodegradation in the environment. Attempts to isolate TCP-degrading organisms using enrichment cultivation have failed. A potential biodegradation pathway starts with hydrolyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37558fc4df7b5227b183bfe3a9087c69
https://doi.org/10.1128/aem.01620-14
https://doi.org/10.1128/aem.01620-14
Autor:
Yuji Nagata, Michal Otyepka, Martina Pavlová, Rebecca C. Wade, Pavel Banáš, Jiri Damborsky, Radka Chaloupková, Masataka Tsuda, Zbynek Prokop, Martin Klvana
Publikováno v:
Nature Chemical Biology. 5:727-733
Engineering enzymes to degrade anthropogenic compounds efficiently is challenging. We obtained Rhodococcus rhodochrous haloalkane dehalogenase mutants with up to 32-fold higher activity than wild type toward the toxic, recalcitrant anthropogenic comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7df58ab1fd2c03148fabc1aa6f55ae
https://doi.org/10.1038/nchembio.205
https://doi.org/10.1038/nchembio.205
Autor:
Martina Pavlová, Andrea Jesenská, Martin Klvaňa, Jiří Damborský, Hana Konečná, Yuji Nagata, Zbyněk Prokop, Takashi Sato, Masataka Tsuda
Publikováno v:
Journal of Structural Biology. 157:384-392
Haloalkane dehalogenase DhmA from Mycobacterium avium N85 showed poor expression and low stability when produced in Escherichia coli. Here, we present expression DhmA in newly constructed pK4RP rhodococcal expression system in a soluble and stable fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc8e6d0117d0e9027274a4bb5a1449f
https://doi.org/10.1016/j.jsb.2006.09.004
https://doi.org/10.1016/j.jsb.2006.09.004
Autor:
Michal Strouhal, M. Bartos, Marta Monincová, Andrea Jesenská, Yuji Nagata, Jiri Damborsky, Zbynek Prokop, Radka Chaloupková, Petra Möbius, Iva Tesínská, Martina Pavlová, Ivan Rychlik, Ivo Pavlik
Publikováno v:
Applied and Environmental Microbiology. 71:6736-6745
Haloalkane dehalogenases are enzymes that catalyze the cleavage of the carbon-halogen bond by a hydrolytic mechanism. Genomes of Mycobacterium tuberculosis and M. bovis contain at least two open reading frames coding for the polypeptides showing a hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b6257f6df2e459115facf3ccf0e668
https://doi.org/10.1128/aem.71.11.6736-6745.2005
https://doi.org/10.1128/aem.71.11.6736-6745.2005
Autor:
Jana Sýkorová, Masataka Tsuda, Andrea Jesenská, Jiří Damborský, Marta Monincová, Martina Pavlová, Yuji Nagata, Zbyňek Prokop, Radka Chaloupková
Publikováno v:
Journal of Biological Chemistry. 278:52622-52628
Structural comparison of three different haloalkane dehalogenases suggested that substrate specificity of these bacterial enzymes could be significantly influenced by the size and shape of their entrance tunnels. The surface residue leucine 177 posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0474a72fa2929bf2039ffb39efec6a
https://doi.org/10.1074/jbc.m306762200
https://doi.org/10.1074/jbc.m306762200
Autor:
Petr Kulhánek, Alena Stsiapanava, Zbynek Prokop, Jan Dohnálek, Ivana Kuta-Smatanova, Jiri Damborsky, Martina Pavlová, Tana Koudelakova, Martin Klvana, Radka Chaloupková, Rebecca C. Wade, Michal Kuty, Pavel Dvorak
Publikováno v:
Journal of molecular biology. 392(5)
Eight mutants of the DhaA haloalkane dehalogenase carrying mutations at the residues lining two tunnels, previously observed by protein X-ray crystallography, were constructed and biochemically characterized. The mutants showed distinct catalytic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f653dec8e938a775e493cc9c0d48217b
https://pubmed.ncbi.nlm.nih.gov/19577578
https://pubmed.ncbi.nlm.nih.gov/19577578
Autor:
Kateřina Božková, Martina Pavlová, Karel Chroust, Jan Mendel, Zbyněk Prokop, Jiří Damborský, Veronika Zajı´čková, Zdeněk Kubát
Publikováno v:
Chemosphere. 67(1)
Halogenated aliphatic compounds were evaluated for toxic and genotoxic effects in the somatic mutation and recombination test employing Drosophila melanogaster. The tested chemicals included chlorinated, brominated and iodinated; mono-, di- and tri-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b36a1db0ba038b24dce57ce146c532a
https://pubmed.ncbi.nlm.nih.gov/17113125
https://pubmed.ncbi.nlm.nih.gov/17113125