Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Martina Parrini"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103290- (2024)
Summary: The ability of rodents to effectively navigate in an environment is based on trial-and-error learning and flexible decision-making and can be analyzed via navigational trajectories. We present a protocol for studying the deployment of search
Externí odkaz:
https://doaj.org/article/0332dd59d9a741599378065f6e9cd5a2
Autor:
Ilaria Colombi, Mohit Rastogi, Martina Parrini, Micol Alberti, Alberto Potenzieri, Mariam Marie Chellali, Silvia Rosati, Michela Chiappalone, Marina Nanni, Andrea Contestabile, Laura Cancedda
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109438- (2024)
Summary: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in adults. Depolarizing GABA responses have been well characterized at neuronal-population average level during typical neurodevelopment and partially in brain disorders.
Externí odkaz:
https://doaj.org/article/e9afb1124fca46278e48afa6190b7852
Autor:
Ilaria Colombi, Ilias Ziogas, Amos Fumagalli, Martina Parrini, Annalisa Savardi, Micol Alberti, Andrea Contestabile, Laura Cancedda
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S84- (2023)
Externí odkaz:
https://doaj.org/article/0564df5b9bc64712a5cb563d8b75c7ef
Autor:
Paola Vagni, Laura E. Perlini, Naïg A. L. Chenais, Tommaso Marchetti, Martina Parrini, Andrea Contestabile, Laura Cancedda, Diego Ghezzi
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Inherited retinal dystrophies (IRDs) are a large and heterogeneous group of degenerative diseases caused by mutations in various genes. Given the favorable anatomical and immunological characteristics of the eye, gene therapy holds great potential fo
Externí odkaz:
https://doaj.org/article/8a50ca66298f4c9e882c2c253a5f5c1b
Autor:
Ilaria Colombi, Mohit Rastogi, Martina Parrini, Micol Alberti, Michela Chiappalone, Marina Nanni, Andrea Contestabile, Laura Cancedda
GABA is the main inhibitory neurotransmitter in adults. Depolarizing/excitatory GABA responses have been well characterized at the level of neuronal-population average during typical neurodevelopment and partially in pathology. However, no investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a9f2434011e59ac46f05595141d351
https://doi.org/10.1101/2023.05.25.542321
https://doi.org/10.1101/2023.05.25.542321
Autor:
Federica Piccardi, Federico Mingozzi, Giovanni Morelli, Giuseppe Ronzitti, Micol Alberti, Ilaria Colombi, Martina Parrini, Anna Rocchi, Marina Nanni, Laura Cancedda, Andrea Contestabile, Shovan Naskar, Severine Charles
Publikováno v:
Molecular Therapy. 29:3072-3092
A common feature of diverse brain disorders is the alteration of GABA-mediated inhibition because of aberrant, intracellular chloride homeostasis induced by changes in the expression and/or function of chloride transporters. Notably, pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4e2553c80950392f377324fb80efde
https://doi.org/10.1016/j.ymthe.2021.05.023
https://doi.org/10.1016/j.ymthe.2021.05.023
Autor:
Laura E. Perlini, Diego Ghezzi, Martina Parrini, Andrea Contestabile, Naïg Aurelia Ludmilla Chenais, Paola Vagni, Tommaso Marchetti, Laura Cancedda
Inherited retinal dystrophies are a large and heterogeneous group of degenerative diseases caused by mutations in various genes. Given the favourable anatomical and immunological characteristics of the eye, gene therapy holds great potential for thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82a7376df8556a4a651ebeabef2aa82
Autor:
Laura Cancedda, Gabriele Deidda, Andrea Contestabile, Enrico Castroflorio, Martina Parrini, Pietro Baldelli, Micol Alberti, Diego Ghezzi, Lucian Medrihan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Down syndrome (DS) is caused by the triplication of human chromosome 21 and represents the most frequent genetic cause of intellectual disability. The trisomic Ts65Dn mouse model of DS shows synaptic deficits and reproduces the essential cognitive di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c6749677f664411e2644b41a76b3d4
https://pubmed.ncbi.nlm.nih.gov/29203796
https://pubmed.ncbi.nlm.nih.gov/29203796
Autor:
Andrea Contestabile, Shovan Naskar, Ignacio F. Bozarth, Laura Cancedda, Gabriele Deidda, Martina Parrini
Down syndrome (DS) is the most frequent genetic cause of intellectual disability, and altered GABAergic transmission through Cl(-)-permeable GABAA receptors (GABAARs) contributes considerably to learning and memory deficits in DS mouse models. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b8d0130634652e45651de37cd46d0c
https://hdl.handle.net/11577/3461162
https://hdl.handle.net/11577/3461162
Autor:
Andrea Contestabile, Laura Cancedda, Micol Alberti, Shovan Naskar, Martina Parrini, Federico Mingozzi, Marina Nanni, Anna Rocchi, Giuseppe Ronzitti
Publikováno v:
Molecular Therapy. 24:S23-S24
Down syndrome (DS) is a genetic disorder caused by the presence of a third copy of chromosome 21. DS affects multiple organs, resulting in characteristic facial features, muscular hypotonia, heart defects, brain development impairment, and varying de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3d22a6991eb4b096851b77bcea672aa
https://doi.org/10.1016/s1525-0016(16)32862-3
https://doi.org/10.1016/s1525-0016(16)32862-3