Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Martina Pagani"'
Autor:
William T. Ralvenius, Elena Neumann, Martina Pagani, Mario A. Acuña, Hendrik Wildner, Dietmar Benke, Nina Fischer, Ana Rostaher, Simon Schwager, Michael Detmar, Katrin Frauenknecht, Adriano Aguzzi, Jed Lee Hubbs, Uwe Rudolph, Claude Favrot, Hanns Ulrich Zeilhofer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Chronic itch affects about 10% of the general population, however current treatments are largely ineffective. Here, the authors show that targeting of inhibitory α2 and α3GABAA receptors reduces itch in mice and in a canine model, suggesting this a
Externí odkaz:
https://doaj.org/article/8993328b421e431ca678a24d0b1b96fb
Autor:
Martina Pagani, Jean-Marc Fritschy, Hendrik Wildner, Helge C. Johannssen, Ladina Hösli, Gioele W. Albisetti, Hanns Ulrich Zeilhofer, Evgenia Platonova
Publikováno v:
The Journal of Neuroscience. 39:2238-2250
Gastrin-releasing peptide (GRP) is a spinal itch transmitter expressed by a small population of dorsal horn interneurons (GRP neurons). The contribution of these neurons to spinal itch relay is still only incompletely understood, and their potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008b07ff2fb1426243ef269b14a054b0
https://doi.org/10.1523/jneurosci.2559-18.2019
https://doi.org/10.1523/jneurosci.2559-18.2019
Autor:
Hendrik Wildner, Gioele W. Albisetti, Martina Pagani, Hanns Ulrich Zeilhofer, Helge C. Johannssen, Mirko Santello, Nandhini Sivakumar
Publikováno v:
Neuron
Neuron, 103 (1)
Neuron, 103 (1)
Summary Spinal transmission of pruritoceptive (itch) signals requires transneuronal signaling by gastrin-releasing peptide (GRP) produced by a subpopulation of dorsal horn excitatory interneurons. These neurons also express the glutamatergic marker v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c253169b416b195e3c29743bc3b8bd35
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106853- (2023)
Summary: The last decade has witnessed massive advancements in high-throughput techniques capable of producing increasingly complex gene expression datasets across time and space and at the resolution of single cells. Yet, the large volume of big dat
Externí odkaz:
https://doaj.org/article/05f3dc61b31d464ca52b504a672cd2ef