Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martina P. Bach"'
Autor:
Marcus Dühren-von Minden, Michael Reth, Thomas Wossning, Martina P. Bach, Kohei Kometani, Hassan Jumaa, Anselm H. C. Horn, Rudolf Übelhart, Tomohiro Kurosaki, Eva Hug, Christoph J. Binder, Dimitrios Tsiantoulas, Heinrich Sticht, Lars Nitschke
Publikováno v:
Nature Immunology. 16:534-543
Mature B cells express immunoglobulin M (IgM)- and IgD-isotype B cell antigen receptors, but the importance of IgD for B cell function has been unclear. By using a cellular in vitro system and corresponding mouse models, we found that antigens with l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4008f32625c3b509f6c38a56cf348193
https://doi.org/10.1038/ni.3141
https://doi.org/10.1038/ni.3141
Autor:
Hassan Jumaa, Marjolein J. W. de Bruijn, Martina P. Bach, Anne E. Corcoran, Hedda Wardemann, Markus Josef Zoller, Rudi W. Hendriks, Louise S. Matheson, Van B. T. Ta
Publikováno v:
Journal of Immunology, 189(10), 4842-4851. American Association of Immunologists
Mice deficient for the adapter protein Slp65 (also known as Blnk), a key component in precursor-BCR (pre-BCR) signaling, spontaneously develop pre-B cell leukemia. In these leukemias, proliferation is thought to be driven by constitutive Jak3/Stat5 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab4b552831d4b4bf1b880c6bd31b52a
https://doi.org/10.4049/jimmunol.1201440
https://doi.org/10.4049/jimmunol.1201440
Publikováno v:
Zeitschrift für Rheumatologie. 73:62-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d59dc77b505d502b921490cb8afc108
https://doi.org/10.1007/s00393-013-1234-6
https://doi.org/10.1007/s00393-013-1234-6
Autor:
Teruhiko Wakayama, Federica Mainoldi, Martina P. Bach, Mikako Maruya, Hassan Jumaa, Osami Kanagawa, Satoshi Kishigami, Rashmi Kumar, Sidonia Fagarasan, Stefano Casola
Publikováno v:
Proceedings of the National Academy of Sciences. 112
In mammals, VDJ recombination is responsible for the establishment of a highly diversified preimmune antibody repertoire. Acquisition of a functional Ig heavy (H) chain variable (V) gene rearrangement is thought to prevent further recombination at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f33eed5525887cdcefb03f465a649d27
https://doi.org/10.1073/pnas.1417988112
https://doi.org/10.1073/pnas.1417988112
Autor:
Katja Zirlik, Markus Werner, Jürgen Ruland, Eva Hug, Christine Dierks, Julian Holch, Robert Zeiser, Martina P. Bach, Hassan Jumaa, Konstanze Pechloff, Clara Sprissler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(3)
The development of hematopoietic neoplasms is often associated with mutations, altered gene expression or chromosomal translocations. Recently, the t(5, 9)(q33;q22) translocation was found in a subset of peripheral T cell lymphomas and was shown to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ae492efa86d0f4ac9001121453e594
https://pubmed.ncbi.nlm.nih.gov/24376268
https://pubmed.ncbi.nlm.nih.gov/24376268
Autor:
Daniel Hofmann, Marie Follo, Martina P. Bach, Elena Surova, Maike Buchner, Thomas Wossning, Rudolf Übelhart, Hedda Wardemann, Katja Zirlik, Hendrik Veelken, Marcus Dühren-von Minden, Hassan Jumaa, Fabian Kohler, Dunja Schneider
Publikováno v:
Nature, 489(7415), 309
B-cell receptor (BCR) signalling in chronic lymphocytic leukaemia (CLL) is found not to be dependent on exogenous antigens; instead, signalling may involve the binding of the BCR heavy-chain complementarity-determining region to self epitopes on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c327ad41a180e49d626e33882c99569a
https://pubmed.ncbi.nlm.nih.gov/22885698
https://pubmed.ncbi.nlm.nih.gov/22885698
Autor:
Cathrin Eschbach, Martina P. Bach, Roberta Pelanda, Ingrid Fidler, Hassan Jumaa, Fabian Kohler, Klaus Rajewsky
Publikováno v:
European journal of immunology. 41(8)
Antibody diversity is generated by a random gene recombination process with the inherent risk of the production of autoreactive specificities. The current view suggests that B cells expressing such specificities are negatively selected at an early de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf2f3ea78a0fc70cdcb1f855e7999c5
https://pubmed.ncbi.nlm.nih.gov/21604259
https://pubmed.ncbi.nlm.nih.gov/21604259
Autor:
Michael Reth, Thomas Wossning, Hassan Jumaa, Martina P. Bach, Cathrin Eschbach, Rudolf Übelhart
Publikováno v:
Nature immunology. 11(8)
Developing B cells express distinct classes of B cell antigen receptors (BCRs) that differ in their heavy chain (HC). Although only muHC is expressed in early stages, deltaHC-containing BCRs dominate on the surface of mature B cells. The reason for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0b885b052b10731e0ce5227658af05
https://pubmed.ncbi.nlm.nih.gov/20622883
https://pubmed.ncbi.nlm.nih.gov/20622883
Autor:
Rudolf Übelhart, Tomohiro Kurosaki, Eva Hug, Kohei Kometani, Martina P. Bach, Christoph J. Binder, Lars Nitschke, Hassan Jumaa, Michael Reth, Thomas Wossning, Heinrich Sticht, Anselm H. C. Horn, Dimitrios Tsiantoulas, Marcus Dühren-von Minden
Publikováno v:
Nature Immunology. 16:785-785
Nat. Immunol. 16, 534–543 (2015); published online 6 April 2015; corrected after print 21 May 2015 In the version of this article initially published, the bottom left plot in Figure 3c, the top right plot in Figure 4a, and the third and bottom plot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::669a24b990c16e74403de88424b49360
https://doi.org/10.1038/ni0715-785d
https://doi.org/10.1038/ni0715-785d