Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martina Muste Sadurni"'
Autor:
Martina Muste Sadurni, Marco Saponaro
Publikováno v:
Applied Biosciences, Vol 2, Iss 3, Pp 459-476 (2023)
Deregulated transcription is a well-known characteristic of cancer cells, with differentially expressed genes being a common feature of several cancers. Often, deregulated transcription is a consequence of alterations in transcription factors (TFs),
Externí odkaz:
https://doaj.org/article/f8c0934d247a4455a935c06ce4a1edef
Autor:
Shaun Scaramuzza, Rebecca M. Jones, Martina Muste Sadurni, Alicja Reynolds-Winczura, Divyasree Poovathumkadavil, Abigail Farrell, Toyoaki Natsume, Patricia Rojas, Cyntia Fernandez Cuesta, Masato T. Kanemaki, Marco Saponaro, Agnieszka Gambus
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of oth
Externí odkaz:
https://doaj.org/article/1ddaed01eda54eabb32edba52fee2e2b
Publikováno v:
The FEBS journalReferences.
RNA polymerase II moves along genes to decode genetic information stored in the mammalian genome into messenger RNA and different forms of non-coding RNA. However, the transcription process is frequently challenged by DNA lesions caused by exogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e155cdbd8ca7f951fa28d362060edf
https://pubmed.ncbi.nlm.nih.gov/35731652
https://pubmed.ncbi.nlm.nih.gov/35731652
Autor:
Shaun Scaramuzza, Martina Muste Sadurni, Divyasree Poovathumkadavil, Toyoaki Natsume, Patricia Rojas, Masato T. Kanemaki, Marco Saponaro, Agnieszka Gambus
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of other human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321e184875841c48508c45d1abe7c6ff
https://doi.org/10.1101/2022.03.23.485338
https://doi.org/10.1101/2022.03.23.485338
Autor:
Patricia Rojas, Jianming Wang, Giovanni Guglielmi, Martina Mustè Sadurnì, Lucas Pavlou, Geoffrey Ho Duen Leung, Vijay Rajagopal, Fabian Spill, Marco Saponaro
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background DNA replication progression can be affected by the presence of physical barriers like the RNA polymerases, leading to replication stress and DNA damage. Nonetheless, we do not know how transcription influences overall DNA replicat
Externí odkaz:
https://doaj.org/article/072a3bf961d1417a9d243d2700149b95