Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martina Morowski"'
Autor:
Elizabeth J. Haining, Alexandra L. Matthews, Peter J. Noy, Hanna M. Romanska, Helen J. Harris, Jeremy Pike, Martina Morowski, Rebecca L. Gavin, Jing Yang, Pierre-Emmanuel Milhiet, Fedor Berditchevski, Bernhard Nieswandt, Natalie S. Poulter, Steve P. Watson, Michael G. Tomlinson
Publikováno v:
Platelets, Vol 28, Iss 7, Pp 629-642 (2017)
The tetraspanins are a superfamily of four-transmembrane proteins, which regulate the trafficking, lateral diffusion and clustering of the transmembrane proteins with which they interact. We have previously shown that tetraspanin Tspan9 is expressed
Externí odkaz:
https://doaj.org/article/450db8670693458ca5e511caed983da9
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107139 (2014)
BACKGROUND: Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity, but may also cause pathological vessel occlusion. Reorganizations of the platelet cytoskeleton and agonist-induced intracellu
Externí odkaz:
https://doaj.org/article/f359d25b51cf4bd188e79c65c1375978
Autor:
Sebastian Hofmann, Attila Braun, Rastislav Pozgaj, Martina Morowski, Timo Vögtle, Bernhard Nieswandt
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115306 (2014)
Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity by forming thrombi at sites of vascular injury. Although the early events of thrombus formation--platelet adhesion and aggregation--have b
Externí odkaz:
https://doaj.org/article/4c41dd9ed8274db8849aa1ff5f55c165
Autor:
Martina Morowski, Deya Cherpokova, Bernhard Nieswandt, Markus Bender, Shuchi Gupta, Markus Spindler
Publikováno v:
Blood. 131(10)
At sites of vascular injury, exposed subendothelial collagens trigger platelet activation and thrombus formation by interacting with the immunoreceptor tyrosine-based activation motif (ITAM)-coupled glycoprotein VI (GPVI) on the platelet surface. Pla
Autor:
Imke Meyer, Najet Debili, Harald Schulze, Sebastian Dütting, Anita Eckly, Cord Brakebusch, Christian Gachet, Bernhard Nieswandt, Martina Morowski, Deya Cherpokova, Georg Krohne, Irina Pleines
Publikováno v:
Blood. 122:3178-3187
Blood platelets are anuclear cell fragments that are essential for blood clotting. Platelets are produced by bone marrow megakaryocytes (MKs), which extend protrusions, or so-called proplatelets, into bone marrow sinusoids. Proplatelet formation requ
Autor:
Martina Morowski, Guido Stoll, Christoph Kleinschnitz, Carsten Deppermann, David Stegner, Peter Kraft, Bernhard Nieswandt
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:1430-1433
Autor:
Bernhard Nieswandt, Christoph Kleinschnitz, Guido Stoll, Timo Vögtle, Peter Kraft, Martina Morowski
Publikováno v:
Blood, 121(24), 4938-4947. The American Society of Hematology
Platelets are essential mediators of hemostasis and thrombosis. Platelet counts (PCs) in humans average 250 platelets/nL, but it is not entirely clear how platelet numbers affect hemostasis and occurrence of thrombotic events. Mice, displaying PCs of
Autor:
Markus Bender, Michael R. Bösl, Thomas Premsler, Bernhard Nieswandt, Shuchi Gupta, Attila Braun, Albert Sickmann, Zoltan Nagy, Martina Morowski, Heike M. Hermanns
Publikováno v:
Circulation Research. 111:1410-1420
Rationale: At sites of vascular injury, exposed subendothelial collagens not only trigger sudden platelet adhesion and aggregation, thereby initiating normal hemostasis, but also can lead to acute ischemic diseases, such as myocardial infarction or s
Autor:
Martina Morowski, Saravanan Subramaniam, Ingo Pragst, Michael Etscheid, Sandip M. Kanse, Ina Thielmann, Bernhard Nieswandt, Per Morten Sandset
Publikováno v:
Thrombosis and haemostasis. 113(4)
SummaryFactor VII (FVII) activating protease (FSAP) is a circulating protease with a putative function in blood coagulation and fibrinolysis. Genetic epidemiological studies have implied a role for FSAP in carotid stenosis, stroke and thrombosis. To
Autor:
Craig E. Hughes, Sarah Schiessl, Stephanie Watson, Daniel Radtke, Bernhard Nieswandt, Martina Morowski, Steve P. Watson, Sebastian Dütting, Timo Vögtle, Heike M. Hermanns, Carmen M. Schäfer, Jochen A. Ackermann, Lars Nitschke
Publikováno v:
Circulation research. 114(3)
Rationale: Platelets are anuclear cell fragments derived from bone marrow megakaryocytes (MKs) that safeguard vascular integrity but may also cause pathological vessel occlusion. One major pathway of platelet activation is triggered by 2 receptors th