Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Martina Moeton"'
Autor:
Josephine Mathilde Elisabeth Tan, Miesje Maxime van der Stoel, Marlene van den Berg, Nienke Marlies van Loon, Martina Moeton, Edwin Scholl, Nicole Neeltje van der Wel, Igor Kovačević, Peter Lodewijk Hordijk, Anke Loregger, Stephan Huveneers, Noam Zelcer
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107944- (2020)
Summary: The endothelial monolayer forms a barrier between the lumen of blood vessels and the underlying tissues. Stable VE-cadherin-based adherens junctions are essential for maintaining this barrier, whereas their remodeling is required for angioge
Externí odkaz:
https://doaj.org/article/d956f3cfee4f47078c64a2d549743b71
Autor:
Anthony Alioui, Julie Dufour, Valerio Leoni, Anke Loregger, Martina Moeton, Luigi Iuliano, Chiara Zerbinati, Amandine Septier, Pierre Val, Allan Fouache, Vincenzo Russo, David H. Volle, Jean-Marc A. Lobaccaro, Noam Zelcer, Silvère Baron
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Treatment of prostate cancer, especially in its advanced stage, is still challenging; therefore, strategies to prevent metastatic dissemination are of great interest. Here the authors reveal a crucial role for liver X receptors in suppressing prostat
Externí odkaz:
https://doaj.org/article/a7676738149c4c3fabf547b879b97f37
Autor:
Emma C L Cook, Jessica K Nelson, Vincenzo Sorrentino, Duco Koenis, Martina Moeton, Saskia Scheij, Roelof Ottenhoff, Boris Bleijlevens, Anke Loregger, Noam Zelcer
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172721 (2017)
Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein, the sterol-responsive Liver X Receptors (LXRs) play an important role owing to their ability to reduce cellular cholest
Externí odkaz:
https://doaj.org/article/ace271f92020402192c273dfc41da462
Autor:
Anthony Alioui, Julie Dufour, Valerio Leoni, Anke Loregger, Martina Moeton, Luigi Iuliano, Chiara Zerbinati, Amandine Septier, Pierre Val, Allan Fouache, Vincenzo Russo, David H. Volle, Jean-Marc A. Lobaccaro, Noam Zelcer, Silvère Baron
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
This paper has been retracted at the request of the authors.
Externí odkaz:
https://doaj.org/article/b42c1d3286ca44b2a0614721c9ad2382
Autor:
Daniela Herrera Moro Chao, Wouter W Kallemeijn, Andre R A Marques, Marie Orre, Roelof Ottenhoff, Cindy van Roomen, Ewout Foppen, Maria C Renner, Martina Moeton, Marco van Eijk, Rolf G Boot, Willem Kamphuis, Elly M Hol, Jan Aten, Hermen S Overkleeft, Andries Kalsbeek, Johannes M F G Aerts
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138107 (2015)
Gaucher disease is characterized by lysosomal accumulation of glucosylceramide due to deficient activity of lysosomal glucocerebrosidase (GBA). In cells, glucosylceramide is also degraded outside lysosomes by the enzyme glucosylceramidase 2 (GBA2) of
Externí odkaz:
https://doaj.org/article/9ff805450a664b2685d2239252277de8
Autor:
Willem Kamphuis, Carlyn Mamber, Martina Moeton, Lieneke Kooijman, Jacqueline A Sluijs, Anne H P Jansen, Monique Verveer, Lody R de Groot, Vanessa D Smith, Sindhoo Rangarajan, José J Rodríguez, Marie Orre, Elly M Hol
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42823 (2012)
Glial fibrillary acidic protein (GFAP) is the main astrocytic intermediate filament (IF). GFAP splice isoforms show differential expression patterns in the human brain. GFAPδ is preferentially expressed by neurogenic astrocytes in the subventricular
Externí odkaz:
https://doaj.org/article/de0deae88a0c4d868c354d93a453fff0
Autor:
Jessica K. Nelson, Nienke M. van Loon, Noam Zelcer, Martina Moeton, Suzanne A.E. van Wouw, Roelof Ottenhoff, Saskia Scheij, Jenina Kingma
Publikováno v:
Atherosclerosis, 315, 1-9. Elsevier Ireland Ltd
Background and aims Cholesterol metabolism is tightly regulated by transcriptional and post-transcriptional mechanisms. Accordingly, dysregulation of cholesterol metabolism is a major risk factor for the development of coronary artery disease and ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadca31bfc399e7a7a2573f7b82e1a09
https://pure.amc.nl/en/publications/regulation-of-intestinal-ldlr-by-the-lxridol-axis(6a64ee1d-17dd-474a-a545-fbf6e6d967c8).html
https://pure.amc.nl/en/publications/regulation-of-intestinal-ldlr-by-the-lxridol-axis(6a64ee1d-17dd-474a-a545-fbf6e6d967c8).html
Autor:
Marlene van den Berg, Noam Zelcer, Nicole N. van der Wel, Igor Kovacevic, Josephine M. E. Tan, Edwin R. Scholl, Peter L. Hordijk, Miesje M. van der Stoel, Anke Loregger, Stephan Huveneers, Nienke M. van Loon, Martina Moeton
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107944-(2020)
Tan, J M E, van der Stoel, M M, van den Berg, M, van Loon, N M, Moeton, M, Scholl, E, van der Wel, N N, Kovačević, I, Hordijk, P L, Loregger, A, Huveneers, S & Zelcer, N 2020, ' The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting ', Cell Reports, vol. 32, no. 5, 107944 . https://doi.org/10.1016/j.celrep.2020.107944
Cell reports, 32(5):107944. Cell Press
Cell Reports, 32(5):107944. Cell Press
Tan, J M E, van der Stoel, M M, van den Berg, M, van Loon, N M, Moeton, M, Scholl, E, van der Wel, N N, Kovačević, I, Hordijk, P L, Loregger, A, Huveneers, S & Zelcer, N 2020, ' The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting ', Cell Reports, vol. 32, no. 5, 107944 . https://doi.org/10.1016/j.celrep.2020.107944
Cell reports, 32(5):107944. Cell Press
Cell Reports, 32(5):107944. Cell Press
Summary: The endothelial monolayer forms a barrier between the lumen of blood vessels and the underlying tissues. Stable VE-cadherin-based adherens junctions are essential for maintaining this barrier, whereas their remodeling is required for angioge
Autor:
Eleonora Aronica, Sophia F A M de Sonnaville, Tasmin Deering, Dick F. Swaab, Lidia De Filippis, Annemiek van Berkel, Rainer Glass, Vanessa Donega, Elly M. Hol, Martina Moeton, Pierre Robe, Jinte Middeldorp, Wilma D.J. van de Berg, Jacqueline A. Sluijs, Angelo Luigi Vescovi, Simone A. van den Berge, Miriam E van Strien
Publikováno v:
Brain communications, 2(2)
Brain Communications
Brain Communications, 2(2)
de Sonnaville, S F A M, van Strien, M E, Middeldorp, J, Sluijs, J A, van den Berge, S A, Moeton, M, Donega, V, van Berkel, A, Deering, T, De Filippis, L, Vescovi, A L, Aronica, E, Glass, R, van de Berg, W D J, Swaab, D F, Robe, P A & Hol, E M 2020, ' The adult human subventricular zone : partial ependymal coverage and proliferative capacity of cerebrospinal fluid ', Brain Communications, vol. 2, no. 2, pp. fcaa150 . https://doi.org/10.1093/braincomms/fcaa150
Brain Communications
Brain Communications, 2(2)
de Sonnaville, S F A M, van Strien, M E, Middeldorp, J, Sluijs, J A, van den Berge, S A, Moeton, M, Donega, V, van Berkel, A, Deering, T, De Filippis, L, Vescovi, A L, Aronica, E, Glass, R, van de Berg, W D J, Swaab, D F, Robe, P A & Hol, E M 2020, ' The adult human subventricular zone : partial ependymal coverage and proliferative capacity of cerebrospinal fluid ', Brain Communications, vol. 2, no. 2, pp. fcaa150 . https://doi.org/10.1093/braincomms/fcaa150
Neurogenesis continues throughout adulthood in specialized regions of the brain. One of these regions is the subventricular zone. During brain development, neurogenesis is regulated by a complex interplay of intrinsic and extrinsic cues that control
Autor:
Saskia Scheij, Sander Kooijman, Vincenzo Sorrentino, Patrick C.N. Rensen, Noam Zelcer, Nienke M. van Loon, Martina Moeton, Johannes H.M. Levels, Roelof Ottenhoff, Jimmy F.P. Berbée, Marion J.J. Gijbels, Reinout L.P. Roscam Abbing
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1785-1795. Lippincott Williams and Wilkins
Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1785-1795. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology, 38(8), 1785-1795
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1785-1795. Lippincott Williams and Wilkins
Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1785-1795. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology, 38(8), 1785-1795
Supplemental Digital Content is available in the text.
Objective— The E3 ubiquitin ligase IDOL (inducible degrader of the LDLR [LDL (low-density lipoprotein) receptor]) is a post-transcriptional regulator of LDLR abundance. Model systems and h
Objective— The E3 ubiquitin ligase IDOL (inducible degrader of the LDLR [LDL (low-density lipoprotein) receptor]) is a post-transcriptional regulator of LDLR abundance. Model systems and h