Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martina Michalova"'
Autor:
Vlastimil Masek, Pavel Starha, Monika Harvanova, Martina Michalova, David Milde, Zdenek Travnicek, Eva Anzenbacherova
Publikováno v:
Biomedical Papers, Vol 159, Iss 3, Pp 382-387 (2015)
Background: We studied the interaction of oxaliplatin derivatives involving cytotoxic adenine-based cyclin-dependent kinase inhibitors, with human liver microsomal cytochrome P450. Methods and Results: The activities of 9 human liver microsomal CYP f
Externí odkaz:
https://doaj.org/article/022115b3fe4944cb96d47d70f0d562c3
Autor:
Ivo Vrobel, Boris Cvek, Petr Dzubak, Martin Mistrik, Tomas Ozdian, Jirina Bartkova, Jiri Bartek, Pavla Pouckova, Jindrich Sedlacek, Jana Vaclavkova, Søren Friis, Marianne Kraus, Zdenek Skrott, Christoph Driessen, Jing Li, Raymond J. Deshaies, Jørgen H. Olsen, Martina Michalova, Pavel Moudry, Klaus Kaae Andersen, Q. Ping Dou, Dusana Majera, Andrea Miklovicova, Marian Hajduch, Jana Mattova, Zsofia Turi, Jan Gursky, Anne Kutt
Publikováno v:
Nature
Cancer incidence is rising and this global challenge is further exacerbated by tumour resistance to available medicines. A promising approach to meet the need for improved cancer treatment is drug repurposing. Here we highlight the potential for repu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c689af484cdd2a531356edebf03453cb
https://pubmed.ncbi.nlm.nih.gov/29211715
https://pubmed.ncbi.nlm.nih.gov/29211715
Autor:
Klaus Kaae Andersen, Søren Friis, Petr Dzubak, Marian Hajduch, Jiři Bartek, Zdenek Skrott, Jana Vaclavkova, Martina Michalova, Pavla Pouckova, Jan Gursky, Boris Cvek, Dusana Majera, Tomas Ozdian, Martin Mistrik
Publikováno v:
Cancer Research. 78:LB-264
Cancer incidence is rising and this global challenge is further exacerbated by resistance of advanced tumors to standard-of-care and emerging precision medicines. A promising approach to such unmet need for innovative and cost-effective cancer treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a9a8f26d544bdfc4dbde18d6cc8cef
https://doi.org/10.1158/1538-7445.am2018-lb-264
https://doi.org/10.1158/1538-7445.am2018-lb-264
Autor:
Eva Anzenbacherova, Pavel Štarha, David Milde, Monika Harvanova, Martina Michalova, Zdenek Travnicek, Vlastimil Mašek
Publikováno v:
Biomedical Papers, Vol 159, Iss 3, Pp 382-387 (2015)
Background: We studied the interaction of oxaliplatin derivatives involving cytotoxic adenine-based cyclin-dependent kinase inhibitors, with human liver microsomal cytochrome P450. Methods and Results: The activities of 9 human liver microsomal CYP f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72422aadef925f7ef38c5dcddddc262e
https://pubmed.ncbi.nlm.nih.gov/25004912
https://pubmed.ncbi.nlm.nih.gov/25004912
Autor:
Marian Hajduch, Milan Urban, Petr Dzubak, Barbora Lišková, Martina Michalova, Jitka Ulrichová, Renata Burianova, Jan Sarek, Adéla Galandáková
Publikováno v:
Cancer Research. 76:2077-2077
Number of active anticancer compounds failed in the drug development due to unfavorable pharmacological properties. Design of pro-drugs is plausible approach to improve drug-like properties of biologically active compounds. Betulinic acid is a well-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885e504ff74771fc55e28565cc8fb192
https://doi.org/10.1158/1538-7445.am2016-2077
https://doi.org/10.1158/1538-7445.am2016-2077