Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Martina Maritan"'
Autor:
Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, Cristina Paissoni, Paola Rognoni, Martina Maritan, Francesca Brambilla, Paolo Milani, Pierluigi Mauri, Carlo Camilloni, Giovanni Palladini, Giampaolo Merlini, Stefano Ricagno, Martino Bolognesi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Immunoglobulin Light Chain Amyloidosis (AL) is the most common systemic amyloidosis occurring in Western countries. Here the authors present the 4.0 Å cryo-EM structure of light chain AL55 fibrils that were isolated from the heart of an AL systemic
Externí odkaz:
https://doaj.org/article/40c2c81167ec45c9bf6f9207f2cd41b5
Autor:
Martina Maritan, Daniele Veggi, Roberta Cozzi, Lucia Dello Iacono, Erika Bartolini, Paola Lo Surdo, Giulietta Maruggi, Glen Spraggon, Matthew J Bottomley, Enrico Malito
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201922 (2018)
Neisserial heparin binding antigen (NHBA) is one of three main recombinant protein antigens in 4CMenB, a vaccine for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B. NHBA is a surface-exposed lipoprotein
Externí odkaz:
https://doaj.org/article/cee79a5c92024499b9bc57caebc05e1d
Autor:
Paola Rognoni, Martina Maritan, Giovanni Palladini, Luisa Diomede, Pietro Sormanni, Giampaolo Merlini, Arianna Ambrosetti, Francesca Lavatelli, Michele Vendruscolo, Paolo Motta, Stefano Ricagno, Giulia Mazzini, Rosaria Russo, Alberto Barbiroli, Margherita Romeo, Martino Bolognesi, Luca Oberti, Masayoshi Tasaki
Publikováno v:
Journal of Molecular Biology. 432:845-860
In light chain amyloidosis (AL), fibrillar deposition of monoclonal immunoglobulin light chains (LCs) in vital organs, such as heart, is associated with their severe dysfunction. In addition to the cellular damage caused by fibril deposition, direct
Autor:
Ricagno, Rosaria Russo, Margherita Romeo, Tim Schulte, Martina Maritan, Luca Oberti, Maria Monica Barzago, Alberto Barbiroli, Carlo Pappone, Luigi Anastasia, Giovanni Palladini, Luisa Diomede, Stefano
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 950
Light chain amyloidosis (AL) is caused by the aberrant overproduction of immunoglobulin light chains (LCs). The resulting abnormally high LC concentrations in blood lead to deposit formation in the heart and other target organs. Organ damage is cause
Autor:
Michaela Medina, Arthur J. Olson, Benjamin A Barad, David S. Goodsell, Ludovic Autin, Adam Gardner, Daniel Fuentes, Martina Maritan, Danielle A. Grotjahn
Publikováno v:
Frontiers in bioinformatics
CellPAINT is an interactive digital tool that allows non-expert users to create illustrations of the molecular structure of cells and viruses. We present a new release with several key enhancements, including the ability to generate custom ingredient
Autor:
Giovanni Palladini, Martino Bolognesi, Francesca Lavatelli, Stefano Ricagno, Paolo Milani, Paola Rognoni, Pierluigi Mauri, Masayoshi Tasaki, Martina Maritan, Francesca Brambilla, Giampaolo Merlini, Cristina Paissoni, Paolo Swuec, Carlo Camilloni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature communications 10 (2019). doi:10.1038/s41467-019-09133-w
info:cnr-pdr/source/autori:Swuec, Paolo; Lavatelli, Francesca; Tasaki, Masayoshi; Paissonil, Cristina; Rognoni, Paola; Maritanl, Martina; Brambilla, Francesca; Milani, Paolo; Mauri, Pierluigi; Camilloni, Carlo; Palladini, Giovanni; Merlini, Giampaolo; Ricagno, Stefano; Bolognesi, Martino/titolo:Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient/doi:10.1038%2Fs41467-019-09133-w/rivista:Nature communications/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Nature Communications
Nature communications 10 (2019). doi:10.1038/s41467-019-09133-w
info:cnr-pdr/source/autori:Swuec, Paolo; Lavatelli, Francesca; Tasaki, Masayoshi; Paissonil, Cristina; Rognoni, Paola; Maritanl, Martina; Brambilla, Francesca; Milani, Paolo; Mauri, Pierluigi; Camilloni, Carlo; Palladini, Giovanni; Merlini, Giampaolo; Ricagno, Stefano; Bolognesi, Martino/titolo:Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient/doi:10.1038%2Fs41467-019-09133-w/rivista:Nature communications/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Systemic light chain amyloidosis (AL) is a life-threatening disease caused by aggregation and deposition of monoclonal immunoglobulin light chains (LC) in target organs. Severity of heart involvement is the most important factor determining prognosis
Autor:
Martina Maritan
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 78:a231-a231
Autor:
Ondrej Strnad, Ngan Luu-Thuy Nguyen, Peter Wonka, Ludovic Autin, Ruwayda Alharbi, Martina Maritan, Peter Mindek, Deng Luo, Ivan Viola, David S. Goodsell, Tobias Klein
Publikováno v:
IEEE transactions on visualization and computer graphics
IEEE Transactions on Visualization and Computer Graphics
IEEE Transactions on Visualization and Computer Graphics
We present a new technique for the rapid modeling and construction of scientifically accurate mesoscale biological models. The resulting 3D models are based on a few 2D microscopy scans and the latest knowledge available about the biological entity,
Autor:
Martina Maritan, Markus W. Covert, Jonathan R. Karr, Ludovic Autin, David S. Goodsell, Arthur J. Olson
Publikováno v:
J Mol Biol
Building structural models of entire cells has been a long-standing cross-discipline challenge for the research community, as it requires an unprecedented level of integration between multiple sources of biological data and enhanced methods for compu
Autor:
Stefano Ricagno, Luca Oberti, Giampaolo Merlini, Giovanni Palladini, Martina Maritan, Francesca Lavatelli, Paola Rognoni, Alberto Barbiroli, Martino Bolognesi, Rosaria Russo
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 26(sup1)
Light chain amyloidosis (LC-AL) is the most common systemic AL. It is caused by the overproduction and the aggregation of toxic and monoclonal immunoglobulin LCs in target organs. Among all the org...