Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice

Autor: Marilina Florio, Angelica Engfors, Patrizia Gena, Jessica Larsson, Alessandro Massaro, Stella Timpka, Martina Kvist Reimer, Per Kjellbom, Eric Beitz, Urban Johanson, Michael Rützler, Giuseppe Calamita

Publikováno v: Cells, Vol 11, Iss 19, p 3118 (2022)

Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isofo

Externí odkaz: https://doaj.org/article/661d4ca979a64e47b3f85e59af6b2c7f

Enhanced insulin sensitivity mediated by adipose tissue browning perturbs islet morphology and hormone secretion in response to autonomic nervous activation in female mice

Autor: Bilal Omar, Martina Kvist-Reimer, Bo Ahrén, Sven Enerbäck

Publikováno v: American journal of physiology. Endocrinology and metabolism. 310(1)

Insulin resistance results in a compensatory increase in insulin secretion to maintain normoglycemia. Conversely, high insulin sensitivity results in reduced insulin secretion to prevent hypoglycemia. The mechanisms for this inverse adaptation are no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef6f91996f7dab568d08f263c24ed05
https://pubmed.ncbi.nlm.nih.gov/26530152

Dose-Dependent Inhibition by Ghrelin of Insulin Secretion in the Mouse

Autor: Giovanni Pacini, Martina Kvist Reimer, Bo Ahrén

Publikováno v: Endocrinology (Philadelphia) 144 (2003): 916–921.
info:cnr-pdr/source/autori:Reimer M., G. Pacini and B. Ahrén/titolo:Dose-dependent inhibition by ghrelin of insulin secretion in the mouse/doi:/rivista:Endocrinology (Philadelphia)/anno:2003/pagina_da:916/pagina_a:921/intervallo_pagine:916–921/volume:144

Ghrelin is produced by stomach oxyntic cells and thought to be involved in the regulation of body weight and food intake. We demonstrate here that the peptide inhibits insulin secretion from overnight-incubated mouse islets in the presence of 8.3, 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ff016d51366cabc213eb7d205d21cc
https://doi.org/10.1210/en.2002-220819

Markedly reduced chronic nociceptive response in mice lacking the PAC1 receptor

Autor: Helen Jongsma, Lina M. E. Pettersson, Yan-zhen Zhang, Martina Kvist Reimer, Martin Kanje, Alexandra Waldenström, Frank Sundler, Nils Danielsen

Publikováno v: Neuroreport. 12:2215-2219

The neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) has been proposed to have a role in nociception. Here we have used the formalin test, thermal laser stimulation and mechanical von Frey stimulation to investigate possible al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae95f5bba9ae38614f6662ef8af4750
https://doi.org/10.1097/00001756-200107200-00034

Increased expression, axonal transport and release of pituitary adenylate cyclase-activating polypeptide in the cultured rat vagus nerve

Autor: K. Moller, Martina Kvist Reimer, Martin Kanje, Jan Fahrenkrug, Jens Hannibal, Frank Sundler

Publikováno v: Neuroscience. 88:213-222

The expression and axonal transport of pituitary adenylate cyclase-activating polypeptide (PACAP) was studied in the cultured vagus nerve of the rat by immunocytochemistry and in situ hybridization. The number of neurons immunoreactive for PACAP incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04878a9b49328a35e1c74ab3c6efd6c5
https://doi.org/10.1016/s0306-4522(98)00240-1