Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Martina Kurejova"'
1
Akademický článek
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
Autor: Ceng Luo, Vijayan Gangadharan, Kiran Kumar Bali, Rou-Gang Xie, Nitin Agarwal, Martina Kurejova, Anke Tappe-Theodor, Irmgard Tegeder, Susanne Feil, Gary Lewin, Erika Polgar, Andrew J Todd, Jens Schlossmann, Franz Hofmann, Da-Lu Liu, San-Jue Hu, Robert Feil, Thomas Kuner, Rohini Kuner
Publikováno v: PLoS Biology, Vol 10, Iss 3, p e1001283 (2012)
Synaptic long-term potentiation (LTP) at spinal neurons directly communicating pain-specific inputs from the periphery to the brain has been proposed to serve as a trigger for pain hypersensitivity in pathological states. Previous studies have functi
Externí odkaz: https://doaj.org/article/d9f9d1624edd4308a0d8e0d8ab9c4916
Zobrazit plný text záznamu
2
Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways
Autor: Christof Niehrs, Walter Birchmeier, Rashmi Kamble, Nitin Agarwal, Rohini Kuner, Martina Kurejova, Blanka Pospisilova, Sebastian Stösser, Manuela Simonetti, Kiran Kumar Bali, Paul A. Heppenstall, Emil Karaulanov
Publikováno v: Neuron. 83(1):104-121
SummaryWnt signaling represents a highly versatile signaling system, which plays diverse and critical roles in various aspects of neural development. Sensory neurons of the dorsal root ganglia require Wnt signaling for initial cell-fate determination
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7971811bad77bb981cd41a74a4573ed
Zobrazit plný text záznamu
4
A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain
Autor: Napoleone Ferrara, Johannes Waltenberger, Hellmut G. Augustin, Vijayan Gangadharan, Deepitha Selvaraj, Martina Kurejova, Kshitij Srivastava, Sebastian Stösser, Paul A. Heppenstall, Masabumi Shibuya, Matthias Schweizerhof, Christoph W. Michalski, Rohini Kuner
Publikováno v: Cancer cell, vol 27, iss 6
Cancer Cell
Summary Cancer pain is a debilitating disorder and a primary determinant of the poor quality of life. Here, we report a non-vascular role for ligands of the Vascular Endothelial Growth Factor (VEGF) family in cancer pain. Tumor-derived VEGF-A, PLGF-2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b675b5dff7f5450111b9cbf47bed286e
https://escholarship.org/uc/item/14v0q3xz
Zobrazit plný text záznamu
5
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity
Autor: Erika Polgár, Andrew J. Todd, Vijayan Gangadharan, Rohini Kuner, Franz Hofmann, Susanne Feil, Nitin Agarwal, Robert Feil, Thomas Kuner, Anke Tappe-Theodor, Gary R. Lewin, Ceng Luo, Rou-Gang Xie, Irmgard Tegeder, Da-Lu Liu, Martina Kurejova, Jens Schlossmann, San-Jue Hu, Kiran Kumar Bali
Publikováno v: PLoS Biology, Vol 10, Iss 3, p e1001283 (2012)
PLoS Biology 10 (3): e1001283.
PLoS Biology
Electrophysiological and behavioral experiments in mice reveal that a cGMP-dependent kinase amplifies neurotransmitter release from peripheral pain sensors, potentiates spinal synapses, and leads to exaggerated pain.
Synaptic long-term potentiat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cc9782b0b3e1d7688492c7ec43a6a7
http://europepmc.org/articles/PMC3302842?pdf=render
Zobrazit plný text záznamu
6
Pain in experimental autoimmune encephalitis: a comparative study between different mouse models
Autor: Jianning Lu, Anke Tappe-Theodor, Ralf A. Linker, Martina Kurejova, Laura Nikita Wirotanseng, Rohini Kuner
Publikováno v: Journal of Neuroinflammation, Vol 9, Iss 1, p 233 (2012)
Journal of Neuroinflammation
Background Pain can be one of the most severe symptoms associated with multiple sclerosis (MS) and develops with varying levels and time courses. MS-related pain is difficult to treat, since very little is known about the mechanisms underlying its de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e0571c47f384e09eb9b27c786581b0
http://archiv.ub.uni-heidelberg.de/volltextserver/21794/
Zobrazit plný text záznamu
7
Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization
Autor: Andrew J. Todd, Rohini Kuner, Anke Tappe-Theodor, Stefan G. Lechner, Michiel Langeslag, Nina Wettschureck, Gary R. Lewin, Stefan Offermanns, Cristina E. Constantin, Gergely G. Nagy, Michaela Kress, Richard I. Wirotanseng, Nitin Agarwal, Irmgard Tegeder, Peter Lepcynzsky, Martina Kurejova
Publikováno v: PainReferences. 153(1)
Peripheral injury or inflammation leads to a release of mediators capable of binding to a variety of ion channels and receptors. Among these are the 7-transmembrane receptors (G protein-coupled receptors) coupling to G(s), G(i/o), G₁₂/₁₃, or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c683ab408616c0d799d2ae1129520f
https://pubmed.ncbi.nlm.nih.gov/22071319
Zobrazit plný text záznamu
8
Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo
Autor: Vijayan Gangadharan, Nitin Agarwal, Martina Kurejova, Stefan Brugger, Imgard Tegeder, Bernhard Bettler, Rohini Kuner
Publikováno v: Molecular Pain, Vol 5, Iss 1, p 68 (2009)
Molecular Pain
Molecular pain, 5. BioMed Central
Molecular Pain; Vol 5
Background γ-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors. GABAB receptors are widely expressed in the central and the per
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b276fdba7ef98eb0e23bd9dea82a9d78
http://www.molecularpain.com/content/5/1/68
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje