Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Martina Koeva"'
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18968 (2011)
The stemness hypothesis states that all stem cells use common mechanisms to regulate self-renewal and multi-lineage potential. However, gene expression meta-analyses at the single gene level have failed to identify a significant number of genes selec
Externí odkaz:
https://doaj.org/article/afcdfeaa45f546a49e3c5b4dc1430a6f
Autor:
E Camilla Forsberg, Emmanuelle Passegué, Susan S Prohaska, Amy J Wagers, Martina Koeva, Joshua M Stuart, Irving L Weissman
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8785 (2010)
Hematopoietic stem cells (HSC) are rare, multipotent cells capable of generating all specialized cells of the blood system. Appropriate regulation of HSC quiescence is thought to be crucial to maintain their lifelong function; however, the molecular
Externí odkaz:
https://doaj.org/article/d429a9bd22a6426687aa097404fbc39e
Autor:
Wesley Hebert, George A. O'Toole, Alina D. Gutu, Samuel M. Moskowitz, Lael M. Yonker, Martina Koeva, Diane Joseph-McCarthy, Frederick M. Ausubel, Jeffrey D. Wager
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Bacterial persisters are a quasidormant subpopulation of cells that are tolerant to antibiotic treatment. The combination of the aminoglycoside tobramycin with fumarate as an antibacterial potentiator utilizes an antipersister strategy that is aimed
Publikováno v:
Pneumologie. 70
Autor:
Stephen W. Eichhorn, Neville E. Sanjana, Saranna Fanning, Sepehr Ehsani, David C. Schöndorf, Vikram Khurana, Martina Koeva, Chee Yeun Chung, M. Inmaculada Barrasa, Marc Vidal, Yali Lou, Ernest Fraenkel, Thomas Gasser, Bryan Joseph San Luis, Nurcan Tuncbag, Charles Boone, Hadar Benyamini, Theresa Bartels, Jian Peng, Bonnie Berger, Michael Costanzo, Daniel F. Tardiff, Susan Lindquist, Andy Nutter-Upham, Michela Deleidi, Pavan K. Auluck, Yelena Freyzon, Quan Zhong, Valeriya Baru, David P. Bartel
Publikováno v:
Elsevier
Cell systems 4(2), 157-170.e14 (2017). doi:10.1016/j.cels.2016.12.011
Cell systems 4(2), 157-170.e14 (2017). doi:10.1016/j.cels.2016.12.011
Numerous genes and molecular pathways are implicated in neurodegenerative proteinopathies, but their inter-relationships are poorly understood. We systematically mapped molecular pathways underlying the toxicity of alpha-synuclein (α-syn), a protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2ea301199d3cf1e3df58f7664e21af
https://orcid.org/0000-0001-7024-0921
https://orcid.org/0000-0001-7024-0921
Autor:
Ernest Fraenkel, Martina Koeva
The cellular environment is a complex and dynamic system of functional molecules. These molecules interact, either transiently or stably, in pathways, which remain poorly mapped despite extensive study. High-throughput experimental methods have allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8587eb3e78fd649cc3118f27895eb0d
https://doi.org/10.1016/b978-0-12-394447-4.40032-5
https://doi.org/10.1016/b978-0-12-394447-4.40032-5
Autor:
Mikko Taipale, Can Kayatekin, Georgios I. Karras, Martina Koeva, Irina Krykbaeva, Kenneth D. Westover, Susan Lindquist
Publikováno v:
Cell. 150(5):987-1001
SummaryHSP90 is a molecular chaperone that associates with numerous substrate proteins called clients. It plays many important roles in human biology and medicine, but determinants of client recognition by HSP90 have remained frustratingly elusive. W
Autor:
Ernest Fraenkel, Leila Pirhaji, Tali Mazor, Martina Koeva, Ferah Yildirim, Deepika Dinesh, Laura Riva, Martin L. Duennwald
Publikováno v:
PMC
In Huntington's disease (HD), polyglutamine expansions in the huntingtin (Htt) protein cause subtle changes in cellular functions that, over-time, lead to neurodegeneration and death. Studies have indicated that activation of the heat shock response
Autor:
Martina Koeva, Lael M. Yonker, Samuel M. Moskowitz, Alina D. Gutu, Frederick M. Ausubel, George A. O'Toole, Diane Joseph-McCarthy, Wesley Hebert
Publikováno v:
Journal of Cystic Fibrosis. 16:S12
Autor:
Irit Ben-Aharon, Susan Lindquist, Luke Whitesell, Salomon M. Stemmer, Ruth Scherz-Shouval, Martina Koeva, Dora Dias-Santagata, Marc L. Mendillo, Sandro Santagata, Lynette M. Sholl, Andrew H. Beck
Publikováno v:
PMC
Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617227aa3f72295af5b518612f8d2618
https://europepmc.org/articles/PMC4249939/
https://europepmc.org/articles/PMC4249939/