Výsledky vyhledávání - "Martina Heldmann"

Protection of mice against Friend retrovirus infection by vaccination with antigen-loaded, spleen-derived dendritic cells

Autor: Simone Schimmer, Ulf Dittmer, Koen Schepers, Thorsten Reuter, Martina Heldmann

Publikováno v: Vaccine. 22:2686-2689

Antigen-loaded dendritic cells (DC) have been shown to induce specific immune responses in vivo. In the current study we used Friend virus (FV) as a model to analyze whether a DC vaccine is capable of inducing protective immunity against retroviral i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b6d26239e32e58d4c8143ea3491f63
https://doi.org/10.1016/j.vaccine.2004.01.005

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MHC class II and CD40 play opposing roles in dendritic cell survival

Autor: Falk Weih, Gabi Terbeck, Martin Leverkus, Christian Linden, Alexander D. McLellan, Eva-B. Bröcker, Martina Heldmann, Eckhart Kämpgen

Publikováno v: European Journal of Immunology. 30:2612-2619

In contrast to very immature dendritic cells (DC), mature DC are largely resistant to death by CD95 (CD95/APO-1) ligation. Investigation of other potential death-inducing ligands showed that mature DC were instead highly susceptible to apoptosis indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966239a8677f83e33c90bc39bd395955
https://doi.org/10.1002/1521-4141(200009)30:9<2612::aid-immu2612>3.0.co

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MHC class II-mediated apoptosis in dendritic cells: a role for membrane-associated and mitochondrial signaling pathways

Autor: Alexander D. McLellan, Martina Heldmann, Eva-B. Bröcker, Eckhart Kämpgen, Martin Leverkus, Norbert Koch, Andreas O. Eggert

Publikováno v: International immunology. 15(8)

Cytotoxic elimination of dendritic cells (DC) in lymphoid tissue represents an important pathway of immune regulation. However, the mechanism of DC removal is still controversial since mature DC are insensitive to death receptor-mediated killing and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be630e3df8a472c57959528d74293b9
https://pubmed.ncbi.nlm.nih.gov/12882837

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Foamy virus capsids require the cognate envelope protein for particle export

Autor: Dirk Lindemann, Thomas Pietschmann, Hanswalter Zentgraf, Martin Heinkelein, Martina Heldmann, Axel Rethwilm

Publikováno v: ResearcherID
Europe PubMed Central

Unlike other subclasses of the Retroviridae the Spumavirinae , its prototype member being the so-called human foamy virus (HFV), require the expression of the envelope (Env) glycoprotein for viral particle egress. Both the murine leukemia virus (MuLV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26bebb6817f4dcfa7488f429f095e2d
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000079122400006&KeyUID=WOS:000079122400006

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