Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Martina Geier"'
Autor:
Mihail Besleaga, Christian Zimmermann, Katharina Ebner, Robert L. Mach, Astrid R. Mach-Aigner, Martina Geier, Anton Glieder, Oliver Spadiut, Julian Kopp
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Heme-incorporating peroxygenases are responsible for electron transport in a multitude of organisms. Yet their application in biocatalysis is hindered due to their challenging recombinant production. Previous studies suggest Komag
Externí odkaz:
https://doaj.org/article/59820955ea6f4b18a7aabf9052b1dd80
Autor:
Veronika Schusterbauer, Jasmin E. Fischer, Sarah Gangl, Lisa Schenzle, Claudia Rinnofner, Martina Geier, Christian Sailer, Anton Glieder, Gerhard G. Thallinger
Publikováno v:
Journal of Fungi, Vol 8, Iss 10, p 992 (2022)
The industrially important non-conventional yeast Komagataella phaffii suffers from low rates of homologous recombination, making site specific genetic engineering tedious. Therefore, genome editing using CRISPR/Cas represents a simple and efficient
Externí odkaz:
https://doaj.org/article/48be46a237994a869938cf2a1695419d
Autor:
Thomas Vogl, Thomas Kickenweiz, Julia Pitzer, Lukas Sturmberger, Astrid Weninger, Bradley W. Biggs, Eva-Maria Köhler, Armin Baumschlager, Jasmin Elgin Fischer, Patrick Hyden, Marlies Wagner, Martina Baumann, Nicole Borth, Martina Geier, Parayil Kumaran Ajikumar, Anton Glieder
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Classic monodirectional promoters are of limited use for multiple gene co-expression. Here the authors generate a library of 168 bidirectional promoters for the yeast K. phaffii (syn. P. pastoris) with diverse expression profiles to optimize metaboli
Externí odkaz:
https://doaj.org/article/12f9d0ca14df49a782c862f7b33af465
Autor:
Thomas Vogl, Thomas Kickenweiz, Julia Pitzer, Lukas Sturmberger, Astrid Weninger, Bradley W. Biggs, Eva-Maria Köhler, Armin Baumschlager, Jasmin Elgin Fischer, Patrick Hyden, Marlies Wagner, Martina Baumann, Nicole Borth, Martina Geier, Parayil Kumaran Ajikumar, Anton Glieder
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21369-z
Externí odkaz:
https://doaj.org/article/98b3c81aafa94d9389bca18df7ba834e
Publikováno v:
AIMS Bioengineering, Vol 2, Iss 4, Pp 423-436 (2015)
With the emergence of synthetic biology and the vast knowledge about individual biocatalytic reactions, the challenge nowadays is to implement whole natural or synthetic pathways into microorganisms. For this purpose balanced enzyme activities throug
Externí odkaz:
https://doaj.org/article/d34cf4e996824f0d943498d8d4de7314
Autor:
Martina Geier, Christoph Brandner, Gernot A. Strohmeier, Mélanie Hall, Franz S. Hartner, Anton Glieder
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1741-1748 (2015)
Many synthetically useful reactions are catalyzed by cofactor-dependent enzymes. As cofactors represent a major cost factor, methods for efficient cofactor regeneration are required especially for large-scale synthetic applications. In order to gener
Externí odkaz:
https://doaj.org/article/64f1655dcc3f4e9b8f251c02536837de
Autor:
Thomas Vogl, Thomas Kickenweiz, Julia Pitzer, Lukas Sturmberger, Astrid Weninger, Bradley W. Biggs, Eva-Maria Köhler, Armin Baumschlager, Jasmin Elgin Fischer, Patrick Hyden, Marlies Wagner, Martina Baumann, Nicole Borth, Martina Geier, Parayil Kumaran Ajikumar, Anton Glieder
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article was updated after publication to add the ORCID ID of the author Thomas Vogl, which was inadvertently omitted, and to include a corrected version of the ‘Description of Additional Supplementary Files’ which ori
Externí odkaz:
https://doaj.org/article/ddbf30238b9e440bbff2c1be29ae7754
Autor:
Julia Pitzer, Kerstin Steiner, Christian Schmid, Viktor K. Schein, Christoph Prause, Claudia Kniely, Michaela Reif, Martina Geier, Elena Pietrich, Tamara Reiter, Philipp Selig, Clemens Stückler, Peter Pöchlauer, Georg Steinkellner, Karl Gruber, Helmut Schwab, Anton Glieder, Wolfgang Kroutil
Publikováno v:
Green Chemistry. 24:5171-5180
This work describes the biocatalytic amidation of l-proline with ammonia, resulting in a process with optimized atom efficiency giving prolinamide in an optically pure form (ee >99%). Detailed enzyme and reaction engineering studies are provided.
Publikováno v:
Angewandte Chemie. 130:13592-13610
Publikováno v:
Angewandte Chemie (International Ed. in English)
Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that cataly