Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Martina Fantin"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56897 (2013)
Nectins are cell adhesion molecules that are widely expressed in the brain. Nectin expression shows a dynamic spatiotemporal regulation, playing a role in neural migratory processes during development. Nectin-1 and nectin-3 and their heterophilic tra
Externí odkaz:
https://doaj.org/article/6335d502ad114915b2cb5b728c34d76e
Autor:
Igor Kraev, Christian Henneberger, Clara Rossetti, Lisa Conboy, Lene B Kohler, Martina Fantin, Alistair Jennings, Cesar Venero, Victor Popov, Dmitri Rusakov, Michael G Stewart, Elisabeth Bock, Vladimir Berezin, Carmen Sandi
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23433 (2011)
The key roles played by the neural cell adhesion molecule (NCAM) in plasticity and cognition underscore this membrane protein as a relevant target to develop cognitive-enhancing drugs. However, NCAM is a structurally and functionally complex molecule
Externí odkaz:
https://doaj.org/article/bacd0e123c7345618ccdd37e34170d89
Autor:
Wassilios G. Meissner, M. Biran, J.M. Franconi, Fares Bassil, Martina Fantin, Pierre-Olivier Fernagut, François Tison
Publikováno v:
Synapse. 68:98-106
Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by a progressive degeneration of the striatonigral, olivo-ponto-cerebellar, and autonomic systems. Glial cytoplasmic inclusions (GCIs) containing alpha-synuclein represent th
Autor:
Martina Fantin, Lene B. Køhler, Carmen Sandi, Clara Rossetti, Claus Christensen, Vladimir Berezin, Elisabeth Bock
Publikováno v:
European Journal of Cell Biology. 89:817-827
Neural cell adhesion molecule (NCAM)-mediated cell adhesion results in activation of intracellular signaling cascades that lead to cellular responses such as neurite outgrowth, neuronal survival, and modulation of synaptic activity associated with co
Publikováno v:
Journal of Neurochemistry. 106:957-968
We previously demonstrated that NMDA receptors containing the NR2A or NR2B subunits differentially regulate striatal output pathways. We now investigate whether such a differential control is altered under parkinsonian conditions and whether subunit
Publikováno v:
Journal of Neurochemistry. 103:2200-2211
Triple probe microdialysis was employed to investigate whether striatal NR2A and NR2B subunit containing NMDA receptors regulate the activity of striato-pallidal and striato-nigral projection neurons. Probes were implanted in the striatum, ipsilatera
Publikováno v:
British Journal of Pharmacology. 152:549-555
Background and purpose: Nocistatin (NST) is a neuropeptide generated from cleavage of the nociceptin/orphanin FQ (N/OFQ) precursor. Evidence has been presented that NST acts as a functional antagonist of N/OFQ, although NST receptor and transduction
Autor:
Michele Morari, Martina Fantin
Publikováno v:
The Analyst. 140(11)
By using multi-probe microdialysis we previously demonstrated that endogenous glutamate differentially regulates the activity of the striatal output pathways in vivo, through N-methyl-D-aspartate (NMDA) receptors containing the GluN2A or GluN2B subun
Autor:
Brian M. Cox, Martina Fantin, Severo Salvadori, Flora Mela, Beata Buzas, Patrizia Romualdi, Rainer K. Reinscheid, Michele Morari, Michele Simonato, Sanzio Candeletti, Manuela Di Benedetto, Silvia Zucchini, Remo Guerrini, Jeffrey M. Brown, Jassir Witta, Matteo Marti
Publikováno v:
The Journal of Neuroscience. 25:9591-9601
The opioid-like neuropeptide nociceptin/orphanin FQ (N/OFQ) and its receptor (NOP) are expressed in the substantia nigra (SN), a brain area containing dopamine neurons that degenerate in Parkinson's disease. Endogenous N/OFQ facilitates nigral glutam
Autor:
Michael A. van der Kooij, Olivia Zanoletti, Martina Fantin, Carmen Sandi, Krishnendu Ganguly, Leszek Kaczmarek, Celine Fournier, Katarzyna Kalita, Jocelyn Grosse, Emilia Rejmak
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
NATURE COMMUNICATIONS
Chronic stress is a risk factor for the development of psychopathologies characterized by cognitive dysfunction and deregulated social behaviours. Emerging evidence suggests a role for cell adhesion molecules, including nectin-3, in the mechanisms th