Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Martina Di Giovangiulio"'
Autor:
Martina Di Giovangiulio, Angelamaria Rizzo, Eleonora Franzè, Flavio Caprioli, Federica Facciotti, Sara Onali, Agnese Favale, Carmine Stolfi, Hans-Joerg Fehling, Giovanni Monteleone, Massimo C. Fantini
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In normal conditions gut homeostasis is maintained by the suppressive activity of regulatory T cells (Tregs), characterized by the expression of the transcription factor FoxP3. In human inflammatory bowel disease, which is believed to be the conseque
Externí odkaz:
https://doaj.org/article/30a1765e46a64a29b3462f094e11e4c0
Autor:
Martina Di Giovangiulio, Goele Bosmans, Elisa Meroni, Nathalie Stakenborg, Morgane Florens, Giovanna Farro, Pedro J Gomez-Pinilla, Gianluca Matteoli, Guy E Boeckxstaens
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 464-476 (2016)
Abstract Vagotomy (VGX) increases the susceptibility to develop colitis suggesting a crucial role for the cholinergic anti-inflammatory pathway in the regulation of the immune responses. Since oral tolerance and the generation of regulatory T cells (
Externí odkaz:
https://doaj.org/article/b2defb972b1445a9ab8b1403c72d3577
Autor:
Silvia Sedda, Eleonora Franzè, Gerolamo Bevivino, Martina Di Giovangiulio, Angelamaria Rizzo, Alfredo Colantoni, Angela Ortenzi, Enrico Grasso, Mario Giannelli, Giuseppe S. Sica, Massimo Claudio Fantini, Giovanni Monteleone
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
In inflammatory bowel disease (IBD) mucosa, there is over-expression of Smad7, an intracellular inhibitor of the suppressive cytokine transforming growth factor-β1, due to post-transcriptional mechanisms that enhance Smad7 acetylation status thus pr
Externí odkaz:
https://doaj.org/article/505efdefe80344f6968d3d9d061e8037
Autor:
Pedro J Gomez-Pinilla, Giovanna Farro, Martina Di Giovangiulio, Nathalie Stakenborg, Andrea Némethova, Annick de Vries, Adrian Liston, Thorsten B Feyerabend, Hans-Reimer Rodewald, Guy E Boeckxstaens, Gianluca Matteoli
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85304 (2014)
INTRODUCTION: Intestinal manipulation (IM) during abdominal surgery results in intestinal inflammation leading to hypomotility or ileus. Mast cell activation is thought to play a crucial role in the pathophysiology of postoperative ileus (POI). Howev
Externí odkaz:
https://doaj.org/article/66fd3e2ec9e946bebf635b90d4b29638
Autor:
Cathy Cailotto, Pedro J Gomez-Pinilla, Léa M Costes, Jan van der Vliet, Martina Di Giovangiulio, Andrea Némethova, Gianluca Matteoli, Guy E Boeckxstaens
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87785 (2014)
BACKGROUND: Electrical stimulation of the vagus nerve suppresses intestinal inflammation and normalizes gut motility in a mouse model of postoperative ileus. The exact anatomical interaction between the vagus nerve and the intestinal immune system re
Externí odkaz:
https://doaj.org/article/9c920ff3591c4d52b2a1e28fb8c61055
Autor:
Pedro J. Gomez-Pinilla, Giovanna Farro, Martina Di Giovangiulio, Nathalie Stakenborg, Andrea Némethova, Annick de Vries, Adrian Liston, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Guy E. Boeckxstaens, Gianluca Matteoli
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/f9dd2506dd244e52ae38b6ccb55792d6
Autor:
Massimo C. Fantini, Giovanni Monteleone, Claudia Mescoli, Massimo Rugge, Angela Ortenzi, Alfredo Colantoni, Ezio Giorda, Rita Carsetti, Hans-Joerg Fehling, Eleonora Franzè, Carmine Stolfi, Martina Di Giovangiulio, Angelamaria Rizzo
Chronic inflammation drives colitis-associated colorectal cancer (CAC) in inflammatory bowel disease (IBD). FoxP3+ regulatory T cells (Treg) coexpressing the Th17-related transcription factor RORγt accumulate in the lamina propria of IBD patients, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d9bd606f7f38d4763a5404b6718206
https://doi.org/10.1158/2326-6066.c.6548957
https://doi.org/10.1158/2326-6066.c.6548957
Autor:
Massimo C. Fantini, Giovanni Monteleone, Claudia Mescoli, Massimo Rugge, Angela Ortenzi, Alfredo Colantoni, Ezio Giorda, Rita Carsetti, Hans-Joerg Fehling, Eleonora Franzè, Carmine Stolfi, Martina Di Giovangiulio, Angelamaria Rizzo
Suppl. figure and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e7843ffcdaac0a92e958a93c821edd
https://doi.org/10.1158/2326-6066.22538957.v1
https://doi.org/10.1158/2326-6066.22538957.v1
Autor:
Rita Carsetti, Giovanni Monteleone, Claudia Mescoli, Massimo Fantini, Angelamaria Rizzo, Massimo Rugge, Angela Ortenzi, Carmine Stolfi, Eleonora Franzè, Ezio Giorda, Alfredo Colantoni, Martina Di Giovangiulio, Hans-Joerg Fehling
Publikováno v:
Cancer Immunology Research. 6:1082-1092
Chronic inflammation drives colitis-associated colorectal cancer (CAC) in inflammatory bowel disease (IBD). FoxP3+ regulatory T cells (Treg) coexpressing the Th17-related transcription factor RORγt accumulate in the lamina propria of IBD patients, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921b7afb302b5d7551e4133252208ab4
https://doi.org/10.1158/2326-6066.cir-17-0698
https://doi.org/10.1158/2326-6066.cir-17-0698
Autor:
Ivan Monteleone, Martina Di Giovangiulio, Roberta Izzo, Angela Ortenzi, Eleonora Franzè, Irene Marafini, Alfredo Colantoni, Veronica De Simone, Angelamaria Rizzo, Gerolamo Bevivino, Giovanni Monteleone, Silvia Sedda
Publikováno v:
Inflammatory Bowel Diseases. 24:1213-1224
Background In Crohn's disease (CD), the pathogenic immune response is associated with high Smad7, an inhibitor of TGF-β1 signaling. Smad7 knockdown with Mongersen, a specific antisense oligonucleotide-containing compound, restores TGF-β1 activity l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e35f032f8356691b2a643600951c1eb
https://doi.org/10.1093/ibd/izy062
https://doi.org/10.1093/ibd/izy062