Pathophysiological Rationale and Clinical Evidence for Neurohormonal Modulation in Heart Failure with Preserved Ejection Fraction

Autor: Vincenzo Castiglione, Francesco Gentile, Nicolò Ghionzoli, Martina Chiriacò, Giorgia Panichella, Alberto Aimo, Giuseppe Vergaro, Alberto Giannoni, Claudio Passino, Michele Emdin

Publikováno v: Cardiac Failure Review, Vol 9, Iss , Pp - (2023)

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome resulting from the interaction between cardiac diseases, comorbidities and ageing. HFpEF is characterised by the activation of neurohormonal axes, namely of the renin-

Externí odkaz: https://doaj.org/article/bfc42e440699432bbacc817f10f648e5

Glomerular Hyperfiltration Predicts Kidney Function Decline and Mortality in Type 1 and Type 2 Diabetes: A 21-Year Longitudinal Study

Autor: Diego Moriconi, Luca Sacchetta, Martina Chiriacò, Lorenzo Nesti, Giovanna Forotti, Andrea Natali, Anna Solini, Domenico Tricò

Publikováno v: Diabetes Care. 46:845-853

Objective. To evaluate the prognostic value of glomerular hyperfiltration on long-term kidney-related outcomes and mortality in subjects with diabetes. Methods. We retrospectively analyzed 21-year longitudinal data from 314 patients with long-standin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed71c5077c4714a0fb1a70d096d6d73
https://doi.org/10.2337/dc22-2003

Author response for 'Epicardial adipose tissue thickness is associated with reduced peak oxygen consumption and systolic reserve in patients with type 2 diabetes and normal heart function'

Autor: null Lorenzo Nesti, null Nicola Riccardo Pugliese, null Martina Chiriacò, null Domenico Trico, null Simona Baldi, null Andrea Natali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1ae1d492b07b4ee1384dd23f879869b
https://doi.org/10.1111/dom.14861/v2/response1

Mechanisms of cardio-renal protection of sodium-glucose cotransporter-2 inhibitors

Autor: Martina Chiriacò, Domenico Tricò, Anna Solini

Publikováno v: Current opinion in pharmacology. 66

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are glucose-lowering drugs used in the treatment of type 2 diabetes (T2D) that have shown additional cardiac and renal benefits. The mechanisms of SGLT2i-mediated cardiorenal protection include blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8498d55bcfa06211dc6a89ac0593a049
https://pubmed.ncbi.nlm.nih.gov/35964531

Female sex and angiotensin-converting enzyme (ace) insertion/deletion polymorphism amplify the effects of adiposity on blood pressure

Autor: Martina Chiriacò, Domenico Tricò, Simone Leonetti, John R. Petrie, Beverley Balkau, Kurt Højlund, Zoltan Pataky, Peter M Nilsson, Andrea Natali, R.J. Heine, J. Dekker, S. de Rooij, G. Nijpels, W. Boorsma, A. Mitrakou, S. Tournis, K. Kyriakopoulou, P. Thomakos, N. Lalic, K. Lalic, A. Jotic, L. Lukic, M. Civcic, J. Nolan, T.P. Yeow, M. Murphy, C. DeLong, G. Neary, M.P. Colgan, M. Hatunic, T. Konrad, H. Böhles, S. Fuellert, F. Baer, H. Zuchhold, A. Golay, E. Harsch Bobbioni, V. Barthassat, V. Makoundou, T.N.O. Lehmann, T. Merminod, C. Perry, F. Neary, C. MacDougall, K. Shields, L. Malcolm, M. Laakso, U. Salmenniemi, A. Aura, R. Raisanen, U. Ruotsalainen, T. Sistonen, M. Laitinen, H. Saloranta, S.W. Coppack, N. McIntosh, J. Ross, L. Pettersson, P. Khadobaksh, M. Laville, F. Bonnet, A. Brac de la Perriere, C. Louche-Pelissier, C. Maitrepierre, J. Peyrat, S. Beltran, A. Serusclat, R. Gabriel, E.M. Sánchez, R. Carraro, A. Friera, B. Novella, P. Nilsson, M. Persson, G. Östling, O. Melander, P. Burri, P.M. Piatti, L.D. Monti, E. Setola, E. Galluccio, F. Minicucci, A. Colleluori, M. Walker, I.M. Ibrahim, M. Jayapaul, D. Carman, C. Ryan, K. Short, Y. McGrady, D. Richardson, H. Beck-Nielsen, P. Staehr, V. Vestergaard, C. Olsen, L. Hansen, G.B. Bolli, F. Porcellati, C. Fanelli, P. Lucidi, F. Calcinaro, A. Saturni, E. Ferrannini, E. Muscelli, S. Pinnola, M. Kozakova, A. Casolaro, B.D. Astiarraga, G. Mingrone, C. Guidone, A. Favuzzi, P. Di Rocco, C. Anderwald, M. Bischof, M. Promintzer, M. Krebs, M. Mandl, A. Hofer, A. Luger, W. Waldhäusl, M. Roden, J.M. Dekker, A. Mari, J. Petrie, P. Gaffney, G. Boran, A. Kok, S. Patel, A. Gastaldelli, D. Ciociaro, M.T. Guillanneuf, L. Mhamdi, L. Landucci, S. Hills, L. Mota, G. Pacini, C. Cavaggion, A. Tura, S.A. Hills

Publikováno v: Chiriacò, M, Tricò, D, Leonetti, S, Petrie, J R, Balkau, B, Højlund, K, Pataky, Z, Nilsson, P M & Natali, A 2022, ' Female sex and angiotensin-converting enzyme (ace) insertion/deletion polymorphism amplify the effects of adiposity on blood pressure ', Hypertension, vol. 79, no. 1, pp. 36-46 . https://doi.org/10.1161/HYPERTENSIONAHA.121.18048

The pathophysiological link between adiposity and blood pressure is not completely understood, and evidence suggests an influence of sex and genetic determinants. We aimed to identify the relationship between adiposity and blood pressure, independent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ff361101853efb6cdaa15ab7b0ca3d
https://portal.findresearcher.sdu.dk/da/publications/f01e2d41-f64c-487c-a029-c008c59994c1