Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Martina Arici"'
Autor:
Martina Arici, Shih-Che Hsu, Mara Ferrandi, Paolo Barassi, Carlotta Ronchi, Eleonora Torre, Andrea Luraghi, Gwo-Jyh Chang, Patrizia Ferrari, Giuseppe Bianchi, Francesco Peri, Antonio Zaza, Marcella Rocchetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The sarcoplasmic reticulum (SR) Ca2+ ATPase (SERCA2a) depression substantially contributes to diastolic dysfunction in heart failure (HF), suggesting that SERCA2a stimulation may be a mechanism-based HF therapy. Istaroxime is a dr
Externí odkaz:
https://doaj.org/article/782d6a7de41e442dbf9d2b9799220397
Autor:
Claudia Altomare, Chiara Bartolucci, Luca Sala, Carolina Balbi, Jacopo Burrello, Nicole Pietrogiovanna, Alessio Burrello, Sara Bolis, Stefano Panella, Martina Arici, Rolf Krause, Marcella Rocchetti, Stefano Severi, Lucio Barile
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
An in silico hybrid model to derive electrical biomarkers to be used as inputs for an unsupervised learning algorithm to classify differentiated hiPSC-derived cardiomyocytes from a mixed population of ventricular- and atrial-like cells.
Externí odkaz:
https://doaj.org/article/0bdcecbbc1894b2fba760af7ec2fba3d
Autor:
Annalisa Sforza, Vera Vigorelli, Erica Rurali, Gianluca Lorenzo Perrucci, Elisa Gambini, Martina Arici, Alessia Metallo, Raffaella Rinaldi, Paolo Fiorina, Andrea Barbuti, Angela Raucci, Elena Sacco, Marcella Rocchetti, Giulio Pompilio, Stefano Genovese, Maria Cristina Vinci
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Glucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM). Since the impairment in number and function of vasculotrophic circulat
Externí odkaz:
https://doaj.org/article/ee3607bd3f7a4f3da5d4506e483cd996
Autor:
Claudia Altomare, Alessandra Maria Lodrini, Giuseppina Milano, Vanessa Biemmi, Edoardo Lazzarini, Sara Bolis, Nicolò Pernigoni, Eleonora Torre, Martina Arici, Mara Ferrandi, Lucio Barile, Marcella Rocchetti, Giuseppe Vassalli
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundCombined treatment with anthracyclines (e.g., doxorubicin; Dox) and trastuzumab (Trz), a humanized anti-human epidermal growth factor receptor 2 (HER2; ErbB2) antibody, in patients with HER2-positive cancer is limited by cardiotoxicity, as
Externí odkaz:
https://doaj.org/article/4fd0e3964088441d8bba60a7cafdb300
Autor:
Gaspare Mostacciuolo, Claudio Bussadori, Shih-Che Hsu, E. Boz, Claudia Altomare, Martina Arici, Gwo-Jyh Chang, Marcella Rocchetti, Giuseppe Bianchi, Alessandra Maria Lodrini, Emanuela Sala, Paolo Barassi, Mara Ferrandi, Sara Vagni, Patrizia Ferrari, Eleonora Torre
Publikováno v:
Cardiovascular Research. 118:1020-1032
Aims Diabetic cardiomyopathy is a multifactorial disease characterized by an early onset of diastolic dysfunction (DD) that precedes the development of systolic impairment. Mechanisms that can restore cardiac relaxation improving intracellular Ca2+ d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248aece3f5fb74f00cb6818d2c64ea4f
https://doi.org/10.1093/cvr/cvab123
https://doi.org/10.1093/cvr/cvab123
Autor:
Paolo Barassi, SC Hsu, Mara Ferrandi, Marcella Rocchetti, Giuseppe Bianchi, Antonio Zaza, Gwo-Jyh Chang, Francesco Peri, Martina Arici, Carlotta Ronchi, Luraghi A, Patrizia Ferrari, Eleonora Torre
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 384(1)
BackgroundHeart failure (HF) therapeutic toolkit would strongly benefit from the availability of ino-lusitropic agents with a favorable pharmacodynamics and safety profile. Istaroxime is a promising agent, which combines Na+/K+ pump inhibition with S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67772754669ce26efc89f08f8b8bb1a3
https://pubmed.ncbi.nlm.nih.gov/36153005
https://pubmed.ncbi.nlm.nih.gov/36153005
Autor:
Andrea Luraghi, Mara Ferrandi, Paolo Barassi, Martina Arici, Shih-Che Hsu, Eleonora Torre, Carlotta Ronchi, Alessio Romerio, Gwo-Jyh Chang, Patrizia Ferrari, Giuseppe Bianchi, Antonio Zaza, Marcella Rocchetti, Francesco Peri
Publikováno v:
Journal of medicinal chemistry. 65(10)
The stimulation of sarcoplasmic reticulum calcium ATPase SERCA2a emerged as a novel therapeutic strategy to efficiently improve overall cardiac function in heart failure (HF) with reduced arrhythmogenic risk. Istaroxime is a clinical-phase IIb compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed507f2f866247e4e50751e703741bc8
https://pubmed.ncbi.nlm.nih.gov/35580334
https://pubmed.ncbi.nlm.nih.gov/35580334
Autor:
Edoardo Lazzarini, Alessandra Maria Lodrini, Martina Arici, Sara Bolis, Sara Vagni, Stefano Panella, Azucena Rendon-Angel, Melissa Saibene, Alessia Metallo, Tiziano Torre, Giuseppe Vassalli, Pietro Ameri, Claudia Altomare, Marcella Rocchetti, Lucio Barile
Publikováno v:
Theranostics. 12(11)
Rationale: Aging in the heart is a gradual process, involving continuous changes in cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These changes finally lead to adverse organ remodeling and resulting in heart failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d62fd80707985323d3e9ddafcef3630
https://pubmed.ncbi.nlm.nih.gov/35836799
https://pubmed.ncbi.nlm.nih.gov/35836799
Autor:
Stefano Genovese, Erica Rurali, Raffaella Rinaldi, Marcella Rocchetti, Martina Arici, Maria Cristina Vinci, Vera Vigorelli, Giulio Pompilio, Andrea Barbuti, Annalisa Sforza, Elisa Gambini, Paolo Fiorina, Angela Raucci
Background: Glucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM). Since the impairment in number and function of vasculotrophic circulating CD34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c94fa6153c4514abf565203fd3cd7e
https://doi.org/10.21203/rs.3.rs-1093380/v1
https://doi.org/10.21203/rs.3.rs-1093380/v1
Autor:
Annalisa, Sforza, Vera, Vigorelli, Erica, Rurali, Gianluca Lorenzo, Perrucci, Elisa, Gambini, Martina, Arici, Alessia, Metallo, Raffaella, Rinaldi, Paolo, Fiorina, Andrea, Barbuti, Angela, Raucci, Elena, Sacco, Marcella, Rocchetti, Giulio, Pompilio, Stefano, Genovese, Maria Cristina, Vinci
Publikováno v:
Cardiovascular diabetology. 21(1)
Glucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM). Since the impairment in number and function of vasculotrophic circulating CD34In cord bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43498a4cad74aacee7a94e050a3ad4dc
https://pubmed.ncbi.nlm.nih.gov/35397526
https://pubmed.ncbi.nlm.nih.gov/35397526