Phosphoglucomutase Is Not the Target for Galactose Toxicity in Plants

Autor: Martina Althammer, Constantin Blöchl, Roland Reischl, Christian G. Huber, Raimund Tenhaken

Publikováno v: Frontiers in Plant Science, Vol 11 (2020)

Plants synthesize a number of different oligomeric or polymeric sugars containing galactose. During growth and development some of these carbohydrates are metabolized or remodeled releasing galactose as a breakdown product. All plants have establishe

Externí odkaz: https://doaj.org/article/1da8f681dc2f4ec89361635ef2b6cce5

Overexpression of UDP-sugar pyrophosphorylase leads to higher sensitivity towards galactose, providing new insights into the mechanisms of galactose toxicity in plants

Autor: Martina Althammer, Christof Regl, Klaus Herburger, Constantin Blöchl, Elena Voglas, Christian G. Huber, Raimund Tenhaken

Publikováno v: Althammer, M, Regl, C, Herburger, K, Blöchl, C, Voglas, E, Huber, C G & Tenhaken, R 2022, ' Overexpression of UDP-sugar pyrophosphorylase leads to higher sensitivity towards galactose, providing new insights into the mechanisms of galactose toxicity in plants ', Plant Journal, vol. 109, no. 6, pp. 1416-1426 . https://doi.org/10.1111/tpj.15638

Galactose toxicity (Gal-Tox) is a widespread phenomenon ranging from Escherichia coli to mammals and plants. In plants, the predominant pathway for the conversion of galactose into UDP-galactose (UDP-Gal) and UDP-glucose is catalyzed by the enzymes g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7591895bcdfd2054866b55bb83c4609
https://pubmed.ncbi.nlm.nih.gov/34913539