Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Martina A. McAteer"'
Autor:
Stephanie J. Hanna, Terri C. Thayer, Emma J. S. Robinson, Ngoc-Nga Vinh, Nigel Williams, Laurie G. Landry, Robert Andrews, Qi Zhuang Siah, Pia Leete, Rebecca Wyatt, Martina A. McAteer, Maki Nakayama, F. Susan Wong, Jennie H. M. Yang, Timothy I. M. Tree, Johnny Ludvigsson, Colin M. Dayan, Danijela Tatovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Gold nanoparticles (GNPs) have been used in the development of novel therapies as a way of delivery of both stimulatory and tolerogenic peptide cargoes. Here we report that intradermal injection of GNPs loaded with the proinsulin peptide C19-A3, in p
Externí odkaz:
https://doaj.org/article/53e6f7919fde4d98856728343312e345
Autor:
Danijela Tatovic, James Caradoc Birchall, Colin M. Dayan, Jan Mous, Florence Susan Wong, Sion Coulman, Maria Dul, Yotam Levin, Martina A. McAteer, Mark Peakman, Efrat Kochba, Bart O. Roep, P Williams, M. Stefanidou, T Nikolic
Publikováno v:
International Journal of Pharmaceutics. 562:303-312
Antigen specific immunotherapy aims to tolerise patients to specific autoantigens that are responsible for the pathology of an autoimmune disease. Immune tolerance is generated in conditions where the immune response is suppressed and thus gold nanop
Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides
Autor:
Bernard Malissen, Martina A. McAteer, James Caradoc Birchall, Colin M. Dayan, Yotam Levin, F. Susan Wong, Sandrine Henri, Joanne Davies, Efrat Kochba, Ravinder K. Singh, Jan Mous, Camille Malosse, Sion Coulman
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2020, ⟨10.1016/j.nano.2020.102321⟩
International audience; Ultra-small 1-2 nm gold nanoparticles (NP) were conjugated with a poorly-soluble peptide auto-antigen, associated with type 1 diabetes, to modify the peptide pharmacokinetics, following its intradermal delivery. Peptide distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33db1447d49f7807136dd9ea409af277
https://orca.cardiff.ac.uk/id/eprint/136850/1/Using+gold+nanoparticles+for+enhanced+intradermal+delivery+of+poorly+soluble+auto-antigenic+peptides+.pdf
https://orca.cardiff.ac.uk/id/eprint/136850/1/Using+gold+nanoparticles+for+enhanced+intradermal+delivery+of+poorly+soluble+auto-antigenic+peptides+.pdf
Autor:
Asim M Akhtar, Jurgen E Schneider, Stephanie J Chapman, Andrew Jefferson, Janet E Digby, Kulveer Mankia, Ye Chen, Martina A McAteer, Kathryn J Wood, Robin P Choudhury
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12800 (2010)
Vascular cell adhesion molecule-1 (VCAM-1) is upregulated in ischemia reperfusion injury (IRI), persisting after restoration of blood flow. We hypothesized that microparticles of iron oxide targeting VCAM-1 (VCAM-MPIO) would depict "ischemic memory"
Externí odkaz:
https://doaj.org/article/e1e5c649c3b84fba86f9e27331e02ba4
Autor:
Emma Ladds, Paul Alfred Smith, Martina A. McAteer, Nicola R. Sibson, Charles McFadyen, Robin P. Choudhury, Sandra J. Campbell, Daniel C. Anthony, Sébastien Serres, S Mardiguian, Panop Wilainam, Gillian Watt, Fay Saunders
Publikováno v:
The American Journal of Pathology. 182:2071-2081
IL-17 is argued to play an important role in the multiple sclerosis-like disease experimental autoimmune encephalitis (EAE). We investigated the therapeutic effects of anti-IL-17A in a chronic relapsing EAE ABH mouse model using conventional scoring,
Autor:
Robin P. Choudhury, Kieran Clarke, Jürgen E. Schneider, Martina A. McAteer, Keith M. Channon, Damian J. Tyler, Stefan Neubauer
Purpose To systematically investigate intrinsic MR contrast mechanisms that would facilitate plaque characterization and quantification in the aortic root and brachiocephalic artery of ApoE–/– mice ex vivo. Materials and Methods To establish unam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10e280972f7378e425a710e4d72a634
https://ora.ox.ac.uk/objects/uuid:ed77a9bc-8016-4c28-aed5-f35bbe17f747
https://ora.ox.ac.uk/objects/uuid:ed77a9bc-8016-4c28-aed5-f35bbe17f747
Autor:
Robin P. Choudhury, Jürgen E. Schneider, Martina A. McAteer, David R. Greaves, Ziad A. Ali, Nicholas Warrick, Keith M. Channon, Stefan Neubauer, Constantin von zur Mühlen, Christina A. Bursill
Objective— Microparticles of iron oxide (MPIO) distort magnetic field creating marked contrast effects far exceeding their physical size. We hypothesized that antibody-conjugated MPIO would enable magnetic resonance imaging (MRI) of endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a0c27c0d2cab4aafaed490bf0ab64c
https://doi.org/10.1161/atvbaha.107.145466
https://doi.org/10.1161/atvbaha.107.145466
Autor:
Olaf Ansorge, Robin P. Choudhury, T Weissensteiner, Ruth J. Muschel, C Bristow, Alexandre A. Khrapitchev, Martina A. McAteer, W S Carbonell, Nicola R. Sibson, Lukxmi Balathasan, Manuel Sarmiento Soto, Robson, Daniel C. Anthony, Sébastien Serres, Alastair Hamilton
Metastasis to the brain is a leading cause of cancer mortality. The current diagnostic method of gadolinium-enhanced MRI is sensitive only to larger tumors, when therapeutic options are limited. Earlier detection of brain metastases is critical for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581da5f06d59d6d1ca70378a414214f9
https://doi.org/10.1073/pnas.1117412109
https://doi.org/10.1073/pnas.1117412109
Autor:
Daniel C. Anthony, Nicola R. Sibson, Sébastien Serres, Sandra J. Campbell, S Mardiguian, Alexandre Krapitchev, Martina A. McAteer, Asim M. Akhtar, Robin P. Choudhury
Diagnosis of multiple sclerosis (MS) currently requires lesion identification by gadolinium (Gd)-enhanced or T(2)-weighted magnetic resonance imaging (MRI). However, these methods only identify late-stage pathology associated with blood-brain barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec10434b78901112956446b8ac81404
https://ora.ox.ac.uk/objects/uuid:d2b6597c-c05f-4d57-b6b3-9f3483352556
https://ora.ox.ac.uk/objects/uuid:d2b6597c-c05f-4d57-b6b3-9f3483352556
Autor:
Andrew Jefferson, Robin P. Choudhury, Kathryn J. Wood, Martina A. McAteer, Jürgen E. Schneider, S Chapman, Kulveer Mankia, Ye Chen, J Digby, Asim M. Akhtar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12800 (2010)
PLoS ONE, Vol 5, Iss 9, p e12800 (2010)
RATIONALE AND OBJECTIVE: Vascular cell adhesion molecule-1 (VCAM-1) is upregulated in ischemia reperfusion injury (IRI), persisting after restoration of blood flow. We hypothesized that microparticles of iron oxide targeting VCAM-1 (VCAM-MPIO) would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83723570070fbe2cd70722cad0e5f15f
https://doi.org/10.1371/journal.pone.0012800
https://doi.org/10.1371/journal.pone.0012800