Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Martina A. Finetti"'
Autor:
Jocelyn P. Wong, Jason R. Todd, Martina A. Finetti, Frank McCarthy, Malgorzata Broncel, Simon Vyse, Maciej T. Luczynski, Stephen Crosier, Karen A. Ryall, Kate Holmes, Leo S. Payne, Frances Daley, Patty Wai, Andrew Jenks, Barbara Tanos, Aik-Choon Tan, Rachael C. Natrajan, Daniel Williamson, Paul H. Huang
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1265-1275 (2016)
Summary: Subunits of the SWI/SNF chromatin remodeling complex are mutated in a significant proportion of human cancers. Malignant rhabdoid tumors (MRTs) are lethal pediatric cancers characterized by a deficiency in the SWI/SNF subunit SMARCB1. Here,
Externí odkaz:
https://doaj.org/article/1ea3b596e8cc4e36bc647eff1eeb7332
Autor:
Shoaib Ajaib, Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A. Finetti, Arief Gusnanto, Aruna Chakrabarty, Azzam Ismail, Erica Wilson, Frederick S Varn, Bethany Hunter, Andrew Filby, Asa A. Brockman, David McDonald, Roel GW Verhaak, Rebecca A. Ihrie, Lucy F. Stead
Publikováno v:
Neuro-Oncology.
The biological and clinical impact of neoplastic and immune cell type ratios in the glioblastoma (GBM) tumour microenvironment is being realised. Characterising and quantifying cell types within GBMs at scale will facilitate a better understanding of
Autor:
Rhiannon Barrow, James A Poulter, Martina A Finetti, Erica Wilson, Colin A Johnson, Lucy Stead
Publikováno v:
Neuro-Oncology. 24:iv3-iv4
AIMS We have identified two subtypes within glioblastoma (GBM), defined by whether a specific subset of genes is upregulated (Up responders) or downregulated (Down responders) in response the standard treatment. The biology of therapy-driven transcri
Autor:
Georgette Tanner, Martina A Finetti, Steven Pollock, Nora Rippaus, Alexander-Francisco Bruns, Catherine Hogg, Alastair Droop, Anke Bruning-Richardson, Mathew Care, Joseph Wilkinson, Michael Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Susan Short, Lucy Stead
Publikováno v:
Neuro-Oncology. 24:iv1-iv1
AIMS Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite aggressive treatment, a resistant tumour recurs in practically all patients. We therefore aimed to better understand the mechanisms driving this treatment re
Autor:
Claire Keeling, Yura Grabovska, Patricia O'Hare, Stephen Crosier, Jessica C Pickles, Martina A Finetti, Amy R Fairchild, John Anderson, Darren Hargrave, Bernadette Brennan, Thomas S Jacques, Steven C Clifford, Simon Bailey, Daniel Williamson
Publikováno v:
Neuro-Oncology. 24:i7-i7
Malignant Rhabdoid Tumours (MRT) are aggressive paediatric malignancies seen in the central nervous system (Atypical Teratoid Rhabdoid Tumours (ATRT)), and kidney and other soft tissues (Extra-cranial Rhabdoid Tumours (ECRT)). With current therapies
Autor:
Simon Bailey, Stephen Crosier, Emma L. Lishman-Walker, Steven C. Clifford, James P. Hacking, Matthew Selby, Martina A. Finetti, Daniel Williamson, Yura Grabovska
Publikováno v:
Cancer Research. 81:2120-2120
Malignant Rhabdoid Tumors (MRTs) are a textbook model of epigenetic dysregulation within cancer. The biallelic inactivation of a single gene SMARCB1 in >95% of MRTs is sufficient to provoke a lethal pediatric cancer. SMARCB1 encodes a core subunit of
Autor:
Ras A. Ramli, Martina A. Finetti, Matthew P. Selby, Yura Grabovska, Stephen Crosier, Amanda J. Smith, Steven C. Clifford, Daniel Williamson
Publikováno v:
Cancer Research. 77:4875-4875
Malignant Rhabdoid Tumors (MRT) are highly aggressive childhood malignancies characterized by a single mutation; biallelic inactivation of SMARCB1, a component of the SWI/SNF chromatin remodeling complex. These tumors may occur anywhere, most frequen
Autor:
Ajaib, Shoaib, Lodha, Disha, Pollock, Steven, Hemmings, Gemma, Finetti, Martina A, Gusnanto, Arief, Chakrabarty, Aruna, Ismail, Azzam, Wilson, Erica, Varn, Frederick S, Hunter, Bethany, Filby, Andrew, Brockman, Asa A, McDonald, David, Verhaak, Roel G W, Ihrie, Rebecca A, Stead, Lucy F
Publikováno v:
Neuro-Oncology; Jul2023, Vol. 25 Issue 7, p1236-1248, 13p
Publikováno v:
Neuro-Oncology; 2016 Supplement, Vol. 18, piii1-iii6, 22p