Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Martina, Sundqvist"'
Autor:
Kathrin Kläsener, Nadja Herrmann, Liliana Håversen, Timothy Sundell, Martina Sundqvist, Christina Lundqvist, Paul T Manna, Charlotte A Jonsson, Marcella Visentini, Diana Ljung Sass, Sarah McGrath, Kristoffer Grimstad, Alaitz Aranburu, Karin Mellgren, Linda Fogelstrand, Huamei Forsman, Olov Ekwall, Jan Borén, Inger Gjertsson, Michael Reth, Inga‐Lill Mårtensson, Alessandro Camponeschi
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Objectives Paediatric Burkitt's lymphoma (pBL) is the most common childhood non‐Hodgkin B‐cell lymphoma. Despite the encouraging survival rates for most children, treating cases with relapse/resistance to current therapies remains challe
Externí odkaz:
https://doaj.org/article/5334ae4bfcbe40568cef6f2f3b2b82a5
Autor:
Martina Sundqvist, Karin Christenson, Per Wekell, Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix P. Sanchez Klose, Tilmann Kallinich, Amanda Welin, Lena Björkman, Johan Bylund, Anna Karlsson-Bengtsson, Stefan Berg
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We describe a female patient suffering from severe chronic non-bacterial osteomyelitis (CNO) with systemic inflammation and advanced malnutrition and complete deficiency of myeloperoxidase (MPO). CNO is a rare autoinflammatory bone disorder associate
Externí odkaz:
https://doaj.org/article/a633466e18434a24bc26feba26de00e9
Autor:
Muhammad Nawaz, Sepideh Heydarkhan‐Hagvall, Benyapa Tangruksa, Hernán González‐King Garibotti, Yujia Jing, Marco Maugeri, Franziska Kohl, Leif Hultin, Azadeh Reyahi, Alessandro Camponeschi, Bengt Kull, Jonas Christoffersson, Ola Grimsholm, Karin Jennbacken, Martina Sundqvist, John Wiseman, Abdel Wahad Bidar, Lennart Lindfors, Jane Synnergren, Hadi Valadi
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an
Externí odkaz:
https://doaj.org/article/cd41eb4a09a4418b8e2864914218e324
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAdenosine deaminase 2 (ADA2) is a homodimeric, extracellular enzyme and putative growth factor that is produced by cells of the myeloid lineage and, catalytically, deaminates extracellular adenosine to inosine. Loss-of-(catalytic)-function
Externí odkaz:
https://doaj.org/article/282db3e3ac9146178b0ea55e70e04087
Autor:
Jonas Mårtensson, Martina Sundqvist, Asmita Manandhar, Loukas Ieremias, Linjie Zhang, Trond Ulven, Xin Xie, Lena Björkman, Huamei Forsman
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
Neutrophils express the two formyl peptide receptors (FPR1 and FPR2) and the medium-chain fatty acid receptor GPR84. The FPRs are known to define a hierarchy among neutrophil G protein-coupled receptors (GPCRs), that is, the activated FPRs can either
Externí odkaz:
https://doaj.org/article/dd72e55a0052465f9ae403b08c69b7a1
Autor:
Marco Maugeri, Muhammad Nawaz, Alexandros Papadimitriou, Annelie Angerfors, Alessandro Camponeschi, Manli Na, Mikko Hölttä, Pia Skantze, Svante Johansson, Martina Sundqvist, Johnny Lindquist, Tomas Kjellman, Inga-Lill Mårtensson, Tao Jin, Per Sunnerhagen, Sofia Östman, Lennart Lindfors, Hadi Valadi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Lipid nanoparticles (LNPs) are potential platforms for RNA-based therapeutics, but the fate of LNP-RNAs upon internalization into the cell is unclear. Here, the authors show that LNP-mRNAs and ionizable lipids escape the endosomes and are re-released
Externí odkaz:
https://doaj.org/article/8b2d6ac14e79424d88fcb0a687a8a932
Autor:
Qiao Liu, Martina Sundqvist, Wenyan Li, André Holdfeldt, Liang Zhang, Lena Björkman, Johan Bylund, Claes Dahlgren, Cai Wang, Xiaodong Zhao, Huamei Forsman
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Neutrophils and eosinophils are multifunctional granulocytes derived from common myelocytic-committed progenitor cells. Severe congenital neutropenia 1 (SCN1) caused by ELANE mutations is a rare disease characterized by very low n
Externí odkaz:
https://doaj.org/article/8543a9b84c97424ea9de327cf14ab1b0
Autor:
Felix P Sanchez Klose, Halla Björnsdottir, Agnes Dahlstrand Rudin, Tishana Persson, Arsham Khamzeh, Martina Sundqvist, Sara Thorbert-Mros, Régis Dieckmann, Karin Christenson, Johan Bylund
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261724 (2021)
Papillon-Lefèvre Syndrome (PLS) is an autosomal recessive monogenic disease caused by loss-of-function mutations in the CTSC gene, thus preventing the synthesis of the protease Cathepsin C (CTSC) in a proteolytically active form. CTSC is responsible
Externí odkaz:
https://doaj.org/article/ce6edd9f2e2a45018be1dd36e77d07b1
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106185- (2020)
Reactive oxygen species (ROS) generated by the NADPH oxidase are crucial for antimicrobial host defense and also play a role in the regulation of inflammatory processes. Signals generated by formyl peptide receptor 2 (FPR2) activate the neutrophil RO
Externí odkaz:
https://doaj.org/article/3fa53f7955f34f6f8f3749549e5f750b
Autor:
Claes Dahlgren, Simon Lind, Jonas Mårtensson, Lena Björkman, Yanling Wu, Martina Sundqvist, Huamei Forsman
Publikováno v:
Immunological Reviews. 314:69-92
Neutrophils, the most abundant white blood cell in human blood, express receptors that recognize damage/microbial associated pattern molecules of importance for cell recruitment to sites of inflammation. Many of these receptors belong to the family o