Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Martina, Schmittnaegel"'
Autor:
Kevin Kos, Camilla Salvagno, Max D. Wellenstein, Muhammad A. Aslam, Denize A. Meijer, Cheei-Sing Hau, Kim Vrijland, Daphne Kaldenbach, Elisabeth A.M. Raeven, Martina Schmittnaegel, Carola H. Ries, Karin E. de Visser
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
While regulatory T cells (Tregs) and macrophages have been recognized as key orchestrators of cancer-associated immunosuppression, their cellular crosstalk within tumors has been poorly characterized. Here, using spontaneous models for breast cancer,
Externí odkaz:
https://doaj.org/article/6e040c8634824418819d91cace555fe4
Autor:
Cornelia Fischer, Michael W. Munks, Ann B. Hill, Richard A. Kroczek, Stefan Bissinger, Verena Brand, Martina Schmittnaegel, Sabine Imhof-Jung, Eike Hoffmann, Frank Herting, Christian Klein, Hendrik Knoetgen
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Simulating a viral infection in tumor cells is an attractive concept to eliminate tumor cells. We previously reported the molecular design and the in vitro potency of recombinant monoclonal antibodies fused to a virus-derived peptide MHC class I comp
Externí odkaz:
https://doaj.org/article/906184eb45f44cc1b0adba53618c102c
Autor:
Grégory Verdeil, Daniel E. Speiser, Carola H. Ries, Martina Schmittnaegel, Claire Imbratta, Connie B. Gilfillan, Sina Nassiri, Laure Tillé, Marine M. Leblond
Supplementary Figures S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0942e877fdebccde22b1fdb1f14f3c
https://doi.org/10.1158/2326-6066.22542241
https://doi.org/10.1158/2326-6066.22542241
Autor:
Grégory Verdeil, Daniel E. Speiser, Carola H. Ries, Martina Schmittnaegel, Claire Imbratta, Connie B. Gilfillan, Sina Nassiri, Laure Tillé, Marine M. Leblond
Supplementary Tables S1, S2 and S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6194c19a634443738dc530f958fa44
https://doi.org/10.1158/2326-6066.22542238
https://doi.org/10.1158/2326-6066.22542238
Autor:
Grégory Verdeil, Daniel E. Speiser, Carola H. Ries, Martina Schmittnaegel, Claire Imbratta, Connie B. Gilfillan, Sina Nassiri, Laure Tillé, Marine M. Leblond
Bladder cancer is one of the most common malignancies and has poor prognosis for patients with locally advanced, muscle-invasive, disease despite the efficacy of immune checkpoint blockade. To develop more effective immunotherapy strategies, we studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffe5ee0346fba4d57f52bbfb61172e0
https://doi.org/10.1158/2326-6066.c.6549838.v1
https://doi.org/10.1158/2326-6066.c.6549838.v1
Autor:
Hendrik Knoetgen, Christian Klein, Olaf Mundigl, Guy Georges, Eike Hoffmann, Victor Levitsky, Martina Schmittnaegel
Time-lapse fluorescence microscopy of CMV-pp65-specific T cell mediated killing of MCSP+ tumor cells (Colo38) incubated with 15nM of EBV-pMHCI-IgG as control. Constructs are indicated in the respective panel. T cells are stained in red (PKH-26, Sigma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5079efc3200e2704e6a27c78bf03360d
https://doi.org/10.1158/2326-6066.22538494
https://doi.org/10.1158/2326-6066.22538494
Autor:
Hendrik Knoetgen, Christian Klein, Guy Georges, Georg Drabner, Cornelia Fischer, Sabine Imhof-Jung, Eike Hoffmann, Martina Schmittnaegel
Protein sequences of all recombinant fusion proteins described in the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a123c1d81be8204513558fbd9e6046
https://doi.org/10.1158/1535-7163.22503856.v1
https://doi.org/10.1158/1535-7163.22503856.v1
Autor:
Hendrik Knoetgen, Christian Klein, Olaf Mundigl, Guy Georges, Eike Hoffmann, Victor Levitsky, Martina Schmittnaegel
Protein Purification, Flow cytometry, Time lapse live cell imaging by confocal microscopy, Stimulation of PBMCs with homo-and heterodimeric CMV-pMHCI-IgGs, Pharmacokinetic measurement.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2624fd25f701a86517bc1443257dfc23
https://doi.org/10.1158/2326-6066.22538500.v1
https://doi.org/10.1158/2326-6066.22538500.v1
Autor:
Hendrik Knoetgen, Christian Klein, Olaf Mundigl, Guy Georges, Eike Hoffmann, Victor Levitsky, Martina Schmittnaegel
Tumor cells escape immune eradication through multiple mechanisms, including loss of antigenicity and local suppression of effector lymphocytes. To counteract these obstacles, we aimed to direct the unique cytomegalovirus (CMV)-specific immune survei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5dbe865512bdb7f522110cbd2e69e46
https://doi.org/10.1158/2326-6066.c.6548797.v1
https://doi.org/10.1158/2326-6066.c.6548797.v1
Autor:
Hendrik Knoetgen, Christian Klein, Olaf Mundigl, Guy Georges, Eike Hoffmann, Victor Levitsky, Martina Schmittnaegel
Time-lapse fluorescence microscopy of CMV-pp65-specific T cell mediated killing of MCSP+ tumor cells (Colo38) incubated with 15nM of CMV-pMHCI-IgG. Constructs are indicated in the respective panel. T cells are stained in red (PKH-26, Sigma), tumor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5254d6d5553e62d8dff639ce2ade4838
https://doi.org/10.1158/2326-6066.22538497
https://doi.org/10.1158/2326-6066.22538497