Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Martina, Raasholm"'
Autor:
Mirja Harms, Monica M.W. Habib, Simona Nemska, Antonella Nicolò, Andrea Gilg, Nico Preising, Pandian Sokkar, Sara Carmignani, Martina Raasholm, Gilbert Weidinger, Gönül Kizilsavas, Manfred Wagner, Ludger Ständker, Ashraf H. Abadi, Hassan Jumaa, Frank Kirchhoff, Nelly Frossard, Elsa Sanchez-Garcia, Jan Münch
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2694-2708 (2021)
Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse
Externí odkaz:
https://doaj.org/article/877b759cf88f4e9a87e25611fe551bb2
Autor:
Pandian Sokkar, Mirja Harms, Christina Stürzel, Andrea Gilg, Gönül Kizilsavas, Martina Raasholm, Nico Preising, Manfred Wagner, Frank Kirchhoff, Ludger Ständker, Gilbert Weidinger, Benjamin Mayer, Jan Münch, Elsa Sanchez-Garcia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Combining molecular modeling and in vitro bioassays, Sokkar et al. provide an understanding of how EPI-X4, an endogenous peptide antagonist, interacts with its receptor CXCR4. With computational model, validated by mutagenesis studies, they design a
Externí odkaz:
https://doaj.org/article/f993d3d26776456ebe0fc89bf8e4a5df
Autor:
Gemma B. Danks, Heloisa Galbiati, Martina Raasholm, Yamila N. Torres Cleuren, Eivind Valen, Pavla Navratilova, Eric M. Thompson
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic. Results We quantified translation g
Externí odkaz:
https://doaj.org/article/27146042cbff4bafa8ca24be9bc0320f
Autor:
Reiner Noschka, Fabian Gerbl, Florian Löffler, Jan Kubis, Armando A. Rodríguez, Daniel Mayer, Mark Grieshober, Armin Holch, Martina Raasholm, Wolf-Georg Forssmann, Barbara Spellerberg, Sebastian Wiese, Gilbert Weidinger, Ludger Ständker, Steffen Stenger
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Tuberculosis is a highly prevalent infectious disease with more than 1.5 million fatalities each year. Antibiotic treatment is available, but intolerable side effects and an increasing rate of drug-resistant strains of Mycobacterium tuberculosis (Mtb
Externí odkaz:
https://doaj.org/article/4c71e6dd4c7540e7a3b18b1486d5c991
Autor:
Manfred Wagner, Gönül Kizilsavas, Christina M. Stürzel, Ludger Ständker, Gilbert Weidinger, Mirja Harms, Frank Kirchhoff, Elsa Sanchez-Garcia, Benjamin Mayer, Nico Preising, Andrea Gilg, Jan Münch, Pandian Sokkar, Martina Raasholm
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
EPI-X4, a 16-mer fragment of albumin, is a specific endogenous antagonist and inverse agonist of the CXC-motif-chemokine receptor 4 (CXCR4) and thus a key regulator of CXCR4 function. Accordingly, activity-optimized synthetic derivatives of EPI-X4 ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02b6c5ea59caf8af00310f88b9551d5
https://doaj.org/article/f993d3d26776456ebe0fc89bf8e4a5df
https://doaj.org/article/f993d3d26776456ebe0fc89bf8e4a5df
Autor:
Manfred Wagner, Martina Raasholm, Ludger Staendker, Christina M Stuerzel, Andrea Gilg, Mirja Harms, Elsa Sanchez-Garcia, Gilbert Weidinger, Nico Preising, Jan Muench, Pandian Sokkar, Goenuel Kizilsavas
The Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a body-own fragment of albumin and specific antagonist of the CXC-motif-chemokine receptor 4 (CXCR4). CXCR4 signaling is induced by its sole chemokine ligand CXCL12 and is involved in a plethora o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca78cf1a32594ba8e7961ea45173862
https://doi.org/10.1101/2020.10.23.352708
https://doi.org/10.1101/2020.10.23.352708
Autor:
Reiner, Noschka, Fabian, Gerbl, Florian, Löffler, Jan, Kubis, Armando A, Rodríguez, Daniel, Mayer, Mark, Grieshober, Armin, Holch, Martina, Raasholm, Wolf-Georg, Forssmann, Barbara, Spellerberg, Sebastian, Wiese, Gilbert, Weidinger, Ludger, Ständker, Steffen, Stenger
Publikováno v:
Frontiers in Microbiology
Tuberculosis is a highly prevalent infectious disease with more than 1.5 million fatalities each year. Antibiotic treatment is available, but intolerable side effects and an increasing rate of drug-resistant strains of Mycobacterium tuberculosis (Mtb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e48ec8b328aa536dcd702094f5c09d3b
https://pubmed.ncbi.nlm.nih.gov/33537017
https://pubmed.ncbi.nlm.nih.gov/33537017
Autor:
Martina Raasholm, Andrea Gilg, Hassan Jumaa, Sara Carmignani, Ludger Ständker, Nelly Frossard, Antonella Nicolò, Ashraf H. Abadi, Elsa Sanchez-Garcia, Jan Münch, Mirja Harms, Simona Nemska, Manfred Wagner, Frank Kirchhoff, Pandian Sokkar, Gilbert Weidinger, Gönül Kizilsavas, Monica M. W. Habib, Nico Preising
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2694-2708 (2021)
Acta Pharmaceutica Sinica B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2694-2708 (2021)
Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7567a62a142a93676159c3b27eadecbd
https://pubmed.ncbi.nlm.nih.gov/34589390
https://pubmed.ncbi.nlm.nih.gov/34589390
Switching of INCENP paralogs controls transitions in mitotic chromosomal passenger complex functions
Publikováno v:
Cell Cycle
A single inner centromere protein (INCENP) found throughout eukaryotes modulates Aurora B kinase activity and chromosomal passenger complex (CPC) localization, which is essential for timely mitotic progression. It has been proposed that INCENP might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ff81f9ed2de816e18036439a24b98a
Autor:
Martina Raasholm, Abby Long, Coen Campsteijn, Gemma B. Danks, J. Robert Manak, Boris Lenhard, Eric M. Thompson
Publikováno v:
Molecular Biology and Evolution. 32:585-599
Polycistronic mRNAs transcribed from operons are resolved via the trans-splicing of a spliced-leader (SL) RNA. Trans-splicing also occurs at monocistronic transcripts. The phlyogenetically sporadic appearance of trans-splicing and operons has made th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8779bbe9f1a333c349d879fb9f533aa
https://doi.org/10.1093/molbev/msu336
https://doi.org/10.1093/molbev/msu336