Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Martina, Korfei"'
Autor:
Emmeline Marchal-Duval, Méline Homps-Legrand, Antoine Froidure, Madeleine Jaillet, Mada Ghanem, Deneuville Lou, Aurélien Justet, Arnaud Maurac, Aurelie Vadel, Emilie Fortas, Aurelie Cazes, Audrey Joannes, Laura Giersh, Herve Mal, Pierre Mordant, Tristan Piolot, Marin Truchin, Carine M Mounier, Ksenija Schirduan, Martina Korfei, Andreas Gunther, Bernard Mari, Frank Jaschinski, Bruno Crestani, Arnaud A Mailleux
Publikováno v:
eLife, Vol 12 (2023)
Matrix remodeling is a salient feature of idiopathic pulmonary fibrosis (IPF). Targeting cells driving matrix remodeling could be a promising avenue for IPF treatment. Analysis of transcriptomic database identified the mesenchymal transcription facto
Externí odkaz:
https://doaj.org/article/def471563ad64a989723cceb324f9f6d
Autor:
Shashipavan Chillappagari, Julian Schwarz, Vidyasagar Kesireddy, Jessica Knoell, Martina Korfei, Konrad Hoetzenecker, M. Lienhard Schmitz, Christian Behl, Saverio Bellusci, Andreas Guenther, Poornima Mahavadi
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Exaggerated fibroblast proliferation is a well‐known feature in idiopathic pulmonary fibrosis (IPF) which may be – in part – due to insufficient autophagy, a lysosome dependent cellular surveillance pathway. Bcl2‐associate
Externí odkaz:
https://doaj.org/article/6f9ebcc8bb3a4739be193fb80c667671
Autor:
Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha
Publikováno v:
Cells, Vol 11, Iss 12, p 1973 (2022)
Insulin-like growth factor (IGF) signaling controls the development and growth of many organs, including the lung. Loss of function of Igf1 or its receptor Igf1r impairs lung development and leads to neonatal respiratory distress in mice. Although ma
Externí odkaz:
https://doaj.org/article/344e6162dafe47c989dbf8231cb7f25c
Publikováno v:
Cells, Vol 11, Iss 10, p 1626 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited therapeutic options, and there is a huge unmet need for new therapies. A growing body of evidence suggests that the histone deacetylase (HDAC) family of transcri
Externí odkaz:
https://doaj.org/article/1045e90514df4048996a3a0a4cc55d66
Publikováno v:
European Respiratory Review, Vol 29, Iss 156 (2020)
Healthy ageing of the lung involves structural changes but also numerous cell-intrinsic and cell-extrinsic alterations. Among them are the age-related decline in central cellular quality control mechanisms such as redox and protein homeostasis. In th
Externí odkaz:
https://doaj.org/article/33f5de9f6488474384d037c2b053ad30
Autor:
Martina Korfei
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-4 (2018)
Externí odkaz:
https://doaj.org/article/299c07f0c7dd468ebd83b540c3d5c826
Autor:
Martina Korfei, Daniel Stelmaszek, BreAnne MacKenzie, Sylwia Skwarna, Shashipavan Chillappagari, Anna C Bach, Clemens Ruppert, Shigeki Saito, Poornima Mahavadi, Walter Klepetko, Ludger Fink, Werner Seeger, Joseph A Lasky, Soni S Pullamsetti, Oliver H Krämer, Andreas Guenther
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207915 (2018)
BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with a poor prognosis. Pirfenidone is the first antifibrotic agent to be approved for IPF-treatment as it is able to slow down disease progression. However, there is no cura
Externí odkaz:
https://doaj.org/article/9580a869135f483091e8096077b94aed
Autor:
Shigeki Saito, Yan Zhuang, Bin Shan, Svitlana Danchuk, Fayong Luo, Martina Korfei, Andreas Guenther, Joseph A Lasky
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186615 (2017)
BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal disease. Histone deacetylase 6 (HDAC6) alters function and fate of various proteins via deacetylation of lysine residues, and is implicated in TGF-β1-induced EMT (epi
Externí odkaz:
https://doaj.org/article/e3513edce61f4cd49294030347401e17
Autor:
Roxana Wasnick, Martina Korfei, Katarzyna Piskulak, Ingrid Henneke, Jochen Wilhelm, Poornima Mahavadi, Ruth Charlotte Dartsch, Daniel von der Beck, Miriam Koch, Irina Shalashova, Astrid Weiss, Oleksiy Klymenko, Ingolf Askevold, Ludger Fink, Heiko Witt, Holger Hackstein, Elie El Agha, Saverio Bellusci, Walter Klepetko, Melanie Königshoff, Oliver Eickelberg, Ralph Theo Schermuly, Thomas Braun, Werner Seeger, Clemens Ruppert, Andreas Guenther
Publikováno v:
American journal of respiratory and critical care medicine.
Although alveolar epithelial cells type II (AEC2) are chronically injured in Idiopathic Pulmonary Fibrosis (IPF), they contribute to epithelial regeneration in IPF.We hypothezised that Notch signaling may contribute to AEC2 proliferation, de-differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff4ae36af77104900cbd0ea0926f3c9
https://pubmed.ncbi.nlm.nih.gov/36047984
https://pubmed.ncbi.nlm.nih.gov/36047984
