Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Martina, Kiefmann"'
Autor:
Martina Kiefmann, Felix Lehmensiek, Cornelia Ronneburg, Annelie Cuvenhaus, Alwin E. Goetz, Volker Meidl, Cynthia Olotu, Rainer Kiefmann
Publikováno v:
Purinergic Signal
Despite its fundamental role in providing an extensive surface for gas exchange, the alveolar epithelium (AE) serves as an immunological barrier through, e.g., the release of proinflammatory cytokines and secretion of surfactant to prevent alveolar c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780b7b137a8b9a7e34a6633e57833807
https://doi.org/10.1007/s11302-020-09696-0
https://doi.org/10.1007/s11302-020-09696-0
Autor:
Martina Kiefmann, Cynthia Olotu, Bastian Koch, Sven Hammerschmidt, Rainer Kiefmann, Felix Lehmensiek, Ann-Kathrin Riegel
Publikováno v:
J Biol Chem
Bacterial pneumonia is a global health challenge that causes up to 2 million deaths each year. Purinergic signaling plays a pivotal role in healthy alveolar epithelium. Here, we used fluorophore-based analysis and live-cell calcium imaging to address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3518fa3e1868f6fcfbb41106dea043e3
https://doi.org/10.1074/jbc.ra118.007236
https://doi.org/10.1074/jbc.ra118.007236
Autor:
Yan Chen, Joshua M. Spin, Thomas Renné, James B Fink, Tobias Deuse, Evgenios Neofytou, Sonja Schrepfer, Gary Park, Vanessa Taylor, Robert C. Robbins, Hermann Reichenspurner, Rainer Kiefmann, Mandy Stubbendorff, Xiaoqin Hua, Martina Kiefmann
Publikováno v:
Transplantation. 100:1022-1031
Background The efficacy of selective Janus kinase 1/3 inhibitor R507 to prevent obliterative airway disease was analyzed in preclinical airway transplantation models. Methods Orthotopic trachea transplantations were performed between Lewis donors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632195d4328ba11ee79192f622ea66a
https://doi.org/10.1097/tp.0000000000001110
https://doi.org/10.1097/tp.0000000000001110
Autor:
Leonie Schulte-Uentrop, Marc-Oliver Tritt, Kai Heckel, Sonja Schrepfer, Martina Kiefmann, Alwin E. Goetz, Rainer Kiefmann, Paula Keller, Cynthia Olotu, Sascha Tank
Publikováno v:
Thorax. 74(3)
BackgroundIn acute respiratory distress syndrome (ARDS), pulmonary perfusion failure increases physiologic dead space ventilation (VD/VT), leading to a decline of the alveolar CO2 concentration [CO2]iA. Although it has been shown that alveolar hypoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e94277cfd1b248a076d7b085805e61f
https://pubmed.ncbi.nlm.nih.gov/30636195
https://pubmed.ncbi.nlm.nih.gov/30636195
Autor:
Rainer Kiefmann, Marc-Oliver Tritt, Alwin E. Goetz, Paula Keller, Jan Leo Rinnenthal, Cynthia Olotu, Martina Kiefmann, Leonie Schulte-Uentrop, Sascha Tank, Christian Börnchen
In adult respiratory distress syndrome (ARDS) pulmonary perfusion failure increases physiologic dead-space (VD/VT) correlating with mortality. High VD/VT results in alveolar hypocapnia, which has been demonstrated to cause edema formation, atelectasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4708c435e7c7150cefec4c24c028d79d
Autor:
Martina, Kiefmann, Sascha, Tank, Paula, Keller, Christian, Börnchen, Jan L, Rinnenthal, Marc-Oliver, Tritt, Leonie, Schulte-Uentrop, Cynthia, Olotu, Alwin E, Goetz, Rainer, Kiefmann
Publikováno v:
Cell Death & Disease
In adult respiratory distress syndrome (ARDS) pulmonary perfusion failure increases physiologic dead-space (VD/VT) correlating with mortality. High VD/VT results in alveolar hypocapnia, which has been demonstrated to cause edema formation, atelectasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e977c5f4fc0344bf3765a9b589f9b49
https://pubmed.ncbi.nlm.nih.gov/28837149
https://pubmed.ncbi.nlm.nih.gov/28837149
Publikováno v:
A33. ACUTE LUNG INJURY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a20f71b35c34cbdf569c24358c2de9cc
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1343
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1343
Autor:
Rainer Kiefmann, Sascha Tank, Leoni Schulte-Uentrop, Oliver Tritt, Paula Keller, Alwin E. Goetz, Martina Kiefmann, Kai Heckel
Publikováno v:
Nature Precedings
Pulmonary perfusion disorders provoke atelectasis in order to minimize ventilation/perfusion mismatch. However, the underlying mechanisms remain unknown. Because intraalveolar CO2 concentration ([CO2]iA) declines as a consequence of poor pulmonary pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d437a228d55032246c1913f6131b981
https://doi.org/10.1038/npre.2011.6185.1
https://doi.org/10.1038/npre.2011.6185.1