Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Martin von Janta-Lipinski"'
Autor:
Eckart Matthes, Stefan Kurek, Renate Mentel, Martin von Janta-Lipinski, Lutz Gürtler, Ursula Wegner
Publikováno v:
Medical Microbiology and Immunology. 189:91-95
Adenovirus (Ad) infection results in significant morbidity and mortality in both immunocompetent and immunosuppressed hosts. There is currently no licensed chemotherapy effective in dealing with this virus infection. In this study the anti-adenoviral
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:1889-1894
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) was used to explore noncovalent interactions between different peptides and ribose nucleic acids (RNAs). One RNA was mixed together with two or more peptides or vice versa to co
Publikováno v:
Bioorganic & Medicinal Chemistry. 6:701-706
The synthesis of enantiomerically pure carbocyclic adenosine derivatives which have been prepared based on the kinetic resolution of a trans -2-(hydroxymethyl)cyclopentanol derivative is described. Their corresponding triphosphates were evaluated as
Publikováno v:
Antiviral Research. 34:113-119
Antiviral effects of nucleoside analogues against human adenoviruses (ADV) belonging to subgroup B (ADV3) and C (ADV2) were comparatively analysed using focus reduction assay on Fogh and Lund (FL) cells. 3′-Fluoro-2′-deoxythymidine (FTdR), 3′-f
Publikováno v:
Journal of Virological Methods. 59:99-104
A method for screening of antiviral compounds against adenoviruses was established. Test compounds were diluted and plated in chamber slides for tissue culture. Drug-treated, virus-infected cultures were stained with fluorescein isothiocyanate conjug
Autor:
L. S. Victorova, Fritz Theil, Alexander A. Krayevsky, Natalia B. Dyatkina, Dniitry Semizarov, Martin von Janta-Lipinski
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 14:723-726
A method was developed for synthesis of the four stereoisomeric enantiomerically pure 5′-nor carbocyclic nucleosides 4b, ent-4b, 10 and ent-10 starting from the common enantiomerically pure allylic monoacetate 1. Nucleoside analogues were converted
Publikováno v:
Tetrahedron. 51:761-772
A flexible synthesis of the four stereoisomeric enantiomerically pure 5′-nor carbocyclic adenosine analogues 4b , ent - 4b , 5b and ent - 5b starting from the common enantio-merically pure allylic monoacetate 3 has been developed. Each of the nucle
Publikováno v:
Tetrahedron Letters. 35:1961-1964
A flexible synthesis of the four stereoisomeric enantiomerically pure 5′-nor carbocyclic nucleosides 2b, ent-2b, 3b, and ent-3b starting from the common enantiomerically pure allylic monoacetate 1 has been developed.
Autor:
Yong Wu, Eckart Matthes, Martin von Janta-Lipinski, Eugen Uhlmann, Christine Lehmann, Marianne Stulich, Lora Dimitrova
Publikováno v:
Oligonucleotides. 15(4)
Suppression of telomerase activity in tumor cells has been considered as a new anticancer strategy. Here, we present chimeric oligonucleotides (chimeric ODNs) as a new type of telomerase inhibitor that contains differently modified oligomers to addre
Publikováno v:
GBM Annual Fall meeting Berlin/Potsdam 2005. 2005