Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Martin Y. H. Zhang"'
Autor:
Daniela Egli-Spichtig, Martin Y. H. Zhang, Alfred Li, Eva Maria Pastor Arroyo, Nati Hernando, Carsten A. Wagner, Wenhan Chang, Farzana Perwad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine hormone that regulates phosphate and vitamin D metabolism. In models of FGF23 excess, renal deoxyribonuclease 1 (Dnase1) mRNA expression is downregulated. Dnase-1 is an endonucl
Externí odkaz:
https://doaj.org/article/89d7811941be4841a8aed0d4f045fe9c
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and vitamin D metabolism. In patients with acute kidney injury (AKI), FGF23 levels rise rapidly after onset of AKI and are associated with AKI progression and increased mortality. In
Externí odkaz:
https://doaj.org/article/78508e89fbcf46e5904586120b19b19d
Autor:
Anthony A Portale, Martin Y H Zhang, Valentin David, Aline Martin, Yan Jiao, Weikuan Gu, Farzana Perwad
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142924 (2015)
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphate (Pi) and vitamin D homeostasis. The transcription factor, early growth response 1 (egr-1), is a biomarker for FGF23-induced activation of the ERK1/2 signaling pathway. We have sho
Externí odkaz:
https://doaj.org/article/ef41c5028d2e46ddab769e37198c75ab
Autor:
Eva Maria Pastor Arroyo, Carsten A. Wagner, Wenhan Chang, Nati Hernando, Martin Y. H. Zhang, Daniela Egli-Spichtig, Alfred Li, Farzana Perwad
Publikováno v:
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine hormone that regulates phosphate and vitamin D metabolism. In models of FGF23 excess, renal deoxyribonuclease 1 (Dnase1) mRNA expression is downregulated. Dnase-1 is an endonuclease whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523826eb73fabd70f88646acbef2e46
https://escholarship.org/uc/item/3418f2jb
https://escholarship.org/uc/item/3418f2jb
Autor:
Ankanee Chanakul, Martin Y H Zhang, Andrew Louw, Harvey J Armbrecht, Walter L Miller, Anthony A Portale, Farzana Perwad
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72816 (2013)
The mitochondrial enzyme 25-hydroxyvitamin D 1α-hydroxylase, which is encoded by the CYP27B1 gene, converts 25OHD to the biological active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D). Renal 1α-hydroxylase activity is the principal deter
Externí odkaz:
https://doaj.org/article/b8cf89b9e6ee4244a51a3976bb54e96b
Autor:
Benjamin Misselwitz, Carsten A. Wagner, Roland H. Wenger, Michael Föller, V Virginia Ballotta, Murielle Bochud, Menno Pruijm, Isabelle Frey-Wagner, Carla Bettoni, Michal Rajski, Farzana Perwad, Pedro Henrique Imenez Silva, Sandra Hofmann, Gerhard Rogler, Alexander Benedikt Leichtle, Nicole Gehring, David Hoogewijs, Daniel Ackermann, Felix Knauf, Eva María Pastor-Arroyo, Belen Ponte, Daniela Egli-Spichtig, Ian J. Frew, Georg-Martin Fiedler, Florian Lang, Désirée Schönenberger, Martin Y. H. Zhang, Bob Glaudemans
Publikováno v:
Kidney International, 96(4), 890-905. Nature Publishing Group
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis, and its early rise in patients with chronic kidney disease is independently associated with all-cause mortality. Since inflammation is characteristic of chronic kidney disease and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c982e566d66de8f2c28191a073770512
https://research.tue.nl/nl/publications/c463742e-2c74-4c59-863d-d45e8494808c
https://research.tue.nl/nl/publications/c463742e-2c74-4c59-863d-d45e8494808c
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and vitamin D metabolism. In patients with acute kidney injury (AKI), FGF23 levels rise rapidly after onset of AKI and are associated with AKI progression and increased mortality. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba90fa1a2cc022dbfd97dd9d1fea7ba2
https://www.frontiersin.org/article/10.3389/fphys.2018.01494/full
https://www.frontiersin.org/article/10.3389/fphys.2018.01494/full
Autor:
Martin Y. H. Zhang, Renata C. Pereira, Farzana Perwad, H. J. Armbrecht, Anthony A. Portale, Daniel Ranch
Publikováno v:
Endocrinology. 153:1806-1816
The X-linked hypophosphatemic (Hyp) mouse carries a loss-of-function mutation in the phex gene and is characterized by hypophosphatemia due to renal phosphate (Pi) wasting, inappropriately suppressed 1,25-dihydroxyvitamin D [1,25(OH)2D] production, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b39aef157e15635f72d19ee3b25213
https://doi.org/10.1210/en.2011-1831
https://doi.org/10.1210/en.2011-1831
Publikováno v:
Journal of Bone and Mineral Research. 26:1883-1890
In X-linked hypophosphatemia (XLH) and in its murine homologue, the Hyp mouse, increased circulating concentrations of fibroblast growth factor 23 (FGF-23) are critical to the pathogenesis of disordered metabolism of phosphate (P(i)) and 1,25-dihydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6f941db3400b5388e1efaa475c6142
https://doi.org/10.1002/jbmr.401
https://doi.org/10.1002/jbmr.401
Autor:
Martin Y. H. Zhang, Anthony A. Portale, Farzana Perwad, Valentin David, Yan Jiao, Weikuan Gu, Aline Martin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 11, p e0142924 (2015)
PLoS ONE, Vol 10, Iss 11, p e0142924 (2015)
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphate (Pi) and vitamin D homeostasis. The transcription factor, early growth response 1 (egr-1), is a biomarker for FGF23-induced activation of the ERK1/2 signaling pathway. We have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca48a695e2940fd2dc7bfdf356847428
http://europepmc.org/articles/PMC4654537
http://europepmc.org/articles/PMC4654537